Journal of Functional Biomaterials, Volume 14, Issue 12
2023 December - 14 articles
Cover Story: The use of 3D-printed titanium (Ti) cages offers a promising solution for osteoporosis-induced fractures and spinal fusion surgery. These implants, with superior strength compared to other metals, face challenges when used independently, particularly in soft tissue interactions. To address this, a 3D-printed Ti cage was infused with gelatin and hyaluronic acid (G-H) in this study. The G-H-filled mesh structure created micro-sized pores, acting as a bridge for cell migration. The slow release enhanced biocompatibility, up-regulating bone-related gene expressions. In a rabbit femur model, the G-H-coated Ti cage demonstrated superior bone regeneration, filling large holes as a cell migration bridge and expediting bone regrowth. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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