Table of Contents
J. Funct. Biomater., Volume 10, Issue 3 (September 2019)
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Cover Story (view full-size image) Thermogelling biomaterials have application potentials as injectable drug depots or 3D bioprinting. [...] Read more. Thermogelling biomaterials have application potentials as injectable drug depots or 3D bioprinting. Here, we report a new thermogelling polymer based on a poly(2-oxazoline) ABA-type triblock copolymer. Their aqueous solutions were investigated at different concentrations (1–20 wt.%) and in the temperature range of 5–80°C. Only 20 wt.% solution showed thermogelation. Therefore, the rheological and viscoelastic properties were determined using strain and temperature sweeps. The hydrogel exhibited low toxicity against Calu-3 and HEK cells even at high polymer concentrations up to 100 g/L. Investigation of the yields stress showed, that the 3D printing ability is low and needs further adjustments. View this paper.