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Journal of Clinical Medicine, Volume 6, Issue 10

October 2017 - 8 articles

Cover Story: Helminthic therapy has shown considerable promise as a means of alleviating some inflammatory diseases that have proven resistant to pharmaceutical intervention. However, research in the field has been limited by a lack of availability to clinician scientists of a helminth that is relatively benign, non-communicable, affordable, and effectively treats disease. In this study, we describe the production and use of rat tapeworms (HDCs) in a manner that is based on reports from individuals self-treating with helminths, individuals producing helminths for self-treatment, and physicians monitoring patients that are self-treating. The methodology is apparently feasible for any medical center to reproduce, and should prove useful for testing HDCs in clinical trials. View Paper here
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Articles (8)

  • Article
  • Open Access
17 Citations
14,644 Views
20 Pages

Production and Use of Hymenolepis diminuta Cysticercoids as Anti-Inflammatory Therapeutics

  • Kendra Smyth,
  • Claire Morton,
  • Amanda Mathew,
  • Sahil Karuturi,
  • Cliff Haley,
  • Min Zhang,
  • Zoie E. Holzknecht,
  • Chelsea Swanson,
  • Shu S. Lin and
  • William Parker

24 October 2017

Helminthic therapy has shown considerable promise as a means of alleviating some inflammatory diseases that have proven resistant to pharmaceutical intervention. However, research in the field has been limited by a lack of availability to clinician s...

  • Feature Paper
  • Article
  • Open Access
9 Citations
5,526 Views
11 Pages

Integrating Autism Care through a School-Based Intervention Model: A Pilot Study

  • Katherine Dang,
  • Stephen Bent,
  • Brittany Lawton,
  • Tracy Warren,
  • Felicia Widjaja,
  • Michael G. McDonald,
  • Michael Breard,
  • Whitney O’Keefe and
  • Robert L. Hendren

19 October 2017

The purpose of this pilot study is to determine the feasibility of monitoring the progress of children with an autism spectrum disorder (ASD) both in school and at home to promote a school-based integrated care model between parents, teachers, and me...

  • Feature Paper
  • Article
  • Open Access
18 Citations
4,756 Views
9 Pages

Myocardial Expression of Macrophage Migration Inhibitory Factor in Patients with Heart Failure

  • Julia Pohl,
  • Ulrike B. Hendgen-Cotta,
  • Pia Stock,
  • Peter Luedike,
  • Hideo Andreas Baba,
  • Markus Kamler and
  • Tienush Rassaf

13 October 2017

Macrophage migration inhibitory factor (MIF) is a pleiotropic inflammatory protein and contributes to several different inflammatory and ischemic/hypoxic diseases. MIF was shown to be cardioprotective in experimental myocardial ischemia/reperfusion i...

  • Feature Paper
  • Article
  • Open Access
60 Citations
8,958 Views
13 Pages

7 October 2017

Background: Despite growing social acceptance, the LGBTQ population continues to face barriers to healthcare including fear of stigmatization by healthcare providers, and providers’ lack of knowledge about LGBTQ-specific health issues. This analysis...

  • Article
  • Open Access
55 Citations
12,161 Views
16 Pages

Diagnostic Accuracy of FebriDx: A Rapid Test to Detect Immune Responses to Viral and Bacterial Upper Respiratory Infections

  • Wesley H. Self,
  • Jeffrey Rosen,
  • Stephan C. Sharp,
  • Michael R. Filbin,
  • Peter C. Hou,
  • Amisha D. Parekh,
  • Michael C. Kurz and
  • Nathan. I. Shapiro

7 October 2017

C-reactive protein (CRP) and myxovirus resistance protein A (MxA) are associated with bacterial and viral infections, respectively. We conducted a prospective, multicenter, cross-sectional study of adults and children with febrile upper respiratory t...

  • Feature Paper
  • Article
  • Open Access
5 Citations
5,773 Views
12 Pages

History and Outcome of Febrile Neutropenia Outside the Oncology Setting: A Retrospective Study of 76 Cases Related to Non-Chemotherapy Drugs

  • Emmanuel Andrès,
  • Rachel Mourot-Cottet,
  • Frédéric Maloisel,
  • Olivier Keller,
  • Thomas Vogel,
  • François Séverac,
  • Martine Tebacher,
  • Jacques-Eric Gottenberg,
  • Jean-Christophe Weber and
  • Georges Kaltenbach
  • + 4 authors

26 September 2017

Background: Despite major advances in its prevention and treatment, febrile neutropenia remains a most concerning complication of cancer chemotherapy. Outside the oncology setting, however, only few data are currently available on febrile neutropenia...

  • Review
  • Open Access
33 Citations
12,545 Views
11 Pages

25 September 2017

Multiple myeloma (MM) is a hematological malignancy with a poor prognosis, characterized by clonal proliferation of plasma cells in the bone marrow (BM). Relapse due to undetected minimal residual disease (MRD) is the leading cause of death among pat...

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J. Clin. Med. - ISSN 2077-0383