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Journal of Clinical Medicine, Volume 12, Issue 17

September-1 2023 - 332 articles

Cover Story: Asthma is the most frequent chronic childhood disease, affecting up to 20% of children worldwide. This project aims to summarize the most recent evidence regarding maintenance therapy for asthma in children and adolescents. Overall, 10 clinical questions were addressed, and the search strategy included accessing electronic databases and a manual search of gray literature published in the last 25 years. After data extraction and narrative synthesis of results, recommendations were developed using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) methodology. The results showed that the choice of medication depends on the severity of the child’s asthma, phenotype, age, preference, and individual factors. In addition to medications, the identification of comorbidities and modifiable factors is crucial to obtaining good control. View this paper
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Articles (332)

  • Article
  • Open Access
1,523 Views
13 Pages

Circadian Urinary Excretion of Water, and Not Salt, Is Affected by the White Coat Effect

  • Fabio Moretti,
  • Jvan Gianini,
  • Rosaria Del Giorno and
  • Luca Gabutti

2 September 2023

Hypertension is an important morbidity factor. The prognostic consequences of the white-coat effect have been studied extensively. The repercussion on the circadian rhythm of urinary water and salt excretion in the same subgroup remain, conversely, a...

  • Feature Paper
  • Article
  • Open Access
6 Citations
2,031 Views
11 Pages

Postoperative Hiatal Hernia after Ivor Lewis Esophagectomy—A Growing Problem in the Age of Minimally Invasive Surgery

  • Jasmina Kuvendjiska,
  • Robert Jasinski,
  • Julian Hipp,
  • Mira Fink,
  • Stefan Fichtner-Feigl,
  • Markus K. Diener and
  • Jens Hoeppner

1 September 2023

Background: Even though minimally invasive esophagectomy is a safe and oncologically effective procedure, several authors have reported an increased risk of postoperative hiatal hernia (PHH). This study evaluates the incidence and risk factors of PHH...

  • Review
  • Open Access
19 Citations
11,277 Views
24 Pages

1 September 2023

Hypertensive heart disease (HHD) remains a major global public health concern despite the implementation of new approaches for the management of hypertensive patients. The pathological changes occurring during HHD are complex and involve the developm...

  • Feature Paper
  • Article
  • Open Access
10 Citations
3,820 Views
15 Pages

Changes in Peripheral Blood Eosinophil Counts and Risk of Eosinophilic Granulomatosis with Polyangiitis Onset after Initiation of Dupilumab Administration in Adult Patients with Asthma

  • Yoshitomo Kushima,
  • Yasuo Shimizu,
  • Hiromi Hoshi,
  • Ryo Arai,
  • Naoya Ikeda,
  • Yusuke Nakamura,
  • Meitetsu Masawa,
  • Hiroaki Okutomi,
  • Nana Yazawa and
  • Kazuyuki Chibana
  • + 2 authors

1 September 2023

Background: The purpose of this study is to clarify the changes in peripheral blood eosinophil (PBE) counts and eosinophilic granulomatosis with polyangiitis (EGPA) onset in patients with asthma who were treated with dupilumab in clinical practice. M...

  • Review
  • Open Access
6 Citations
3,218 Views
11 Pages

A History of COVID-19 in Pregnancy: A Narrative Review

  • Shahrukh Chaudhry,
  • Omar Aboudawoud and
  • Ghislain Hardy

1 September 2023

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread across the world causing a global pandemic. During a pandemic, it becomes increasing important to evaluate the effects on sp...

  • Review
  • Open Access
5 Citations
4,627 Views
20 Pages

Acute-Onset Retinal Conditions Mimicking Acute Optic Neuritis: Overview and Differential Diagnosis

  • Emanuela Interlandi,
  • Francesco Pellegrini,
  • Chiara Giuffrè,
  • Daniele Cirone,
  • Daniele Brocca,
  • Andrew G. Lee and
  • Giuseppe Casalino

1 September 2023

Acute optic neuritis (AON) is a common cause of sudden visual loss in young patients. Because of the risk of demyelinating disease, patients affected by unilateral or bilateral optic neuritis should be evaluated and treated accordingly. Despite advan...

  • Feature Paper
  • Article
  • Open Access
4 Citations
2,161 Views
8 Pages

Long-Term Outcomes at Skeletal Maturity of Combined Pelvic and Femoral Osteotomy for the Treatment of Legg–Calve–Perthes Disease

  • Christina M. Regan,
  • Alvin W. Su,
  • Anthony A. Stans,
  • Todd A. Milbrandt,
  • A. Noelle Larson,
  • William J. Shaughnessy and
  • Emmanouil Grigoriou

1 September 2023

Surgical treatment for Legg–Calve–Perthes disease (LCPD) is recommended for older children with moderate to severe disease. We sought to determine whether double osteotomies lead to improved radiologic outcomes compared to reported non-op...

  • Systematic Review
  • Open Access
2 Citations
2,267 Views
14 Pages

Three Ablation Techniques for Atrial Fibrillation during Concomitant Cardiac Surgery: A Systematic Review and Network Meta-Analysis

  • Dudy Arman Hanafy,
  • Wahyu Prima Erdianto,
  • Theresia Feline Husen,
  • Ilona Nathania,
  • Ananda Pipphali Vidya,
  • Ruth Angelica,
  • Widya Trianita Suwatri,
  • Pasati Lintangella,
  • Priscillia Prasetyo and
  • Sugisman

1 September 2023

Atrial fibrillation (AF) ablation is a frequent procedure used in concomitant cardiac surgery. However, uncertainty still exists concerning the optimal extent of lesion sets. Hence, the objective of this study was to assess the results of various abl...

  • Article
  • Open Access
1 Citations
1,453 Views
6 Pages

1 September 2023

Metastatic bony disease is a significant health issue, with approximately 700,000 new cases annually that tend to metastasize to bones. The proximal femur in the appendicular skeleton is commonly affected. Our study aimed to investigate mortality rat...

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J. Clin. Med. - ISSN 2077-0383