You are currently viewing a new version of our website. To view the old version click .

Journal of Clinical Medicine, Volume 11, Issue 3

February-1 2022 - 425 articles

Cover Story: Dry age-related macular degeneration (AMD) is a leading cause of irreversible blindness and is characterized by the death of key retinal cells and the propagation of an inflammatory retinal microenvironment. The atrophic form of the disease, for which there are no approved treatments, is characterized by loss of the retinal pigment epithelium (RPE) and the overlying photoreceptors and is associated with activation of the retinal innate immune cells, microglia. While the etiology of AMD is unknown, the Fas receptor has been shown to be a key regulator of death pathway activation and retinal inflammation. Treatment with a Fas inhibitor has the clinical potential to prevent cell death pathway and microglial activation, serving to protect the vision of patients with atrophic AMD. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (425)

  • Article
  • Open Access
37 Citations
6,140 Views
14 Pages

The Influence of Angle Alpha, Angle Kappa, and Optical Aberrations on Visual Outcomes after the Implantation of a High-Addition Trifocal IOL

  • Guadalupe Cervantes-Coste,
  • André Tapia,
  • Claudia Corredor-Ortega,
  • Mariana Osorio,
  • Rafael Valdez,
  • Martha Massaro,
  • Cecilio Velasco-Barona and
  • Roberto Gonzalez-Salinas

8 February 2022

The aim of our investigation was to examine the possible correlations between optical aberrations, angle kappa, angle alpha, and visual outcomes following cataract surgery. In total, 56 eyes of 28 patients were implanted with the Liberty 677MY trifoc...

  • Article
  • Open Access
7 Citations
4,722 Views
14 Pages

Self-Reported Pain and Emotional Reactivity in Bipolar Disorder: A Prospective FACE-BD Study

  • Nathan Risch,
  • Jonathan Dubois,
  • Katia M’bailara,
  • Irena Cussac,
  • Bruno Etain,
  • Raoul Belzeaux,
  • Caroline Dubertret,
  • Emmanuel Haffen,
  • Raymund Schwan and
  • Ludovic Samalin
  • + 6 authors

8 February 2022

In patients with bipolar disorder (BD), pain prevalence is close to 30%. It is important to determine whether pain influences BD course and to identify factors associated with pain in BD in order to guide BD management. This naturalistic, prospective...

  • Article
  • Open Access
9 Citations
3,058 Views
16 Pages

A Systematic Literature Review of the Relationship between Serum Ferritin and Outcomes in Myelodysplastic Syndromes

  • Esther Natalie Oliva,
  • Krystal Huey,
  • Sohan Deshpande,
  • Monica Turner,
  • Madhura Chitnis,
  • Emma Schiller,
  • Derek Tang,
  • Aylin Yucel,
  • Christina Hughes and
  • Farrukh Shah

8 February 2022

Anemia is the most common form of cytopenia in patients with myelodysplastic syndromes (MDS), who require chronic red blood cell transfusions and may present high serum ferritin (SF) levels as a result of iron overload. To better understand the poten...

  • Article
  • Open Access
14 Citations
5,110 Views
12 Pages

Guided Bone Regeneration in the Edentulous Atrophic Maxilla Using Deproteinized Bovine Bone Mineral (DBBM) Combined with Platelet-Rich Fibrin (PRF)—A Prospective Study

  • João Manuel Mendez Caramês,
  • Filipe Araújo Vieira,
  • Gonçalo Bártolo Caramês,
  • Ana Catarina Pinto,
  • Helena Cristina Oliveira Francisco and
  • Duarte Nuno da Silva Marques

8 February 2022

Background: Bone regeneration procedures represent a major challenge in oral surgery. This study aimed to evaluate a composite PRF/particulate xenograft in guided bone regeneration. Methods: Edentulous patients with horizontal ridge deficiencies in t...

  • Article
  • Open Access
2 Citations
3,700 Views
11 Pages

A New System for Periprosthetic Fracture Stabilization—A Biomechanical Comparison

  • Daniel Rau,
  • Gabriele Rußow,
  • Mark Heyland,
  • Dag Wulsten,
  • Clemens Kösters,
  • Werner Schmölz and
  • Sven Märdian

8 February 2022

In recent years, an increase in periprosthetic femur fractures has become apparent due to the increased number of hip replacements. In the case of Vancouver type B1 fractures, locking plate systems offer safe procedures. This study compared the dista...

  • Article
  • Open Access
12 Citations
3,184 Views
14 Pages

Kidney Function According to Different Equations in Patients Admitted to a Cardiology Unit and Impact on Outcome

  • Vincenzo Livio Malavasi,
  • Anna Chiara Valenti,
  • Sara Ruggerini,
  • Marcella Manicardi,
  • Carlotta Orlandi,
  • Daria Sgreccia,
  • Marco Vitolo,
  • Marco Proietti,
  • Gregory Y. H. Lip and
  • Giuseppe Boriani

8 February 2022

Background: This paper aims to evaluate the concordance between the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula and alternative equations and to assess their predictive power for all-cause mortality in unselected patients disc...

  • Article
  • Open Access
17 Citations
4,490 Views
14 Pages

Effects of Moderate Alcohol Consumption in Non-Alcoholic Fatty Liver Disease

  • Peter Lemmer,
  • Paul Manka,
  • Jan Best,
  • Alisan Kahraman,
  • Julia Kälsch,
  • Ramiro Vilchez-Vargas,
  • Alexander Link,
  • Hsin Chiang,
  • Guido Gerken and
  • Ali Canbay
  • + 2 authors

8 February 2022

Alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) have emerged as leading causes of chronic liver diseases worldwide. ALD and NAFLD share several pathophysiological patterns as well as histological features, while clinically...

  • Review
  • Open Access
68 Citations
12,184 Views
27 Pages

8 February 2022

Monocytes and lymphocytes play a key role in physiologic wound healing and might be involved in the impaired mechanisms observed in diabetes. Skin wound macrophages are represented by tissue resident macrophages and infiltrating peripheral blood recr...

  • Article
  • Open Access
38 Citations
4,364 Views
11 Pages

The Ratio of Hemoglobin to Red Cell Distribution Width: A Strong Predictor of Clinical Outcome in Patients with Heart Failure

  • Eldad Rahamim,
  • Donna R. Zwas,
  • Andre Keren,
  • Gabby Elbaz-Greener,
  • Mahsati Ibrahimli,
  • Offer Amir and
  • Israel Gotsman

8 February 2022

Background: Hemoglobin (Hb) is a standard and widely available clinical parameter that predicts clinical outcomes in heart failure (HF) patients. Red cell distribution width (RDW) is also a routinely measured clinical parameter that is predictive of...

  • Article
  • Open Access
5 Citations
3,980 Views
9 Pages

Comparison of Medical and Surgical Treatment in Severe Bell’s Palsy

  • Yong Kim,
  • Seung Geun Yeo,
  • Hwa Sung Rim,
  • Jongha Lee,
  • Dokyoung Kim,
  • Sung Soo Kim,
  • Dong Choon Park,
  • Jae Yong Byun and
  • Sang Hoon Kim

8 February 2022

(1) Background: The effectiveness of decompression surgery for Bell’s palsy is controversial. This study investigated the effects of facial nerve decompression in patients with severe Bell’s palsy who were expected to have a poor prognosi...

of 43

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
J. Clin. Med. - ISSN 2077-0383