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Journal of Clinical Medicine, Volume 10, Issue 12

June-2 2021 - 207 articles

Cover Story: Beyond the optimal management of the traditional Atherosclerotic cardiovascular diseases (ASCVD) risk factors, infections should be considered as an important non-classical risk factor to enable early diagnosis and appropriate treatment. We summarized the currently available evidence regarding the role of inflammation in ASCVD and the association between the particular infections and pathogens on the development and progression of ASCVD. We also speculated about the potential therapeutic implications of the anti-inflammatory and anti-infective drugs on ASCVD outcomes, including drugs routinely administered in patients with ASCVD and novel strategies aiming at residual risk reduction. Considering the emerging association between infections and ASCVD, it is crucial to determine the possible advantages of infection prevention and treatment in patients with ASCVD. View this paper
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Articles (207)

  • Article
  • Open Access
15 Citations
9,748 Views
12 Pages

Computed Tomography in Adults with Bronchiectasis and Nontuberculous Mycobacterial Pulmonary Disease: Typical Imaging Findings

  • Sabine Dettmer,
  • Felix C. Ringshausen,
  • Jan Fuge,
  • Hannah Louise Maske,
  • Tobias Welte,
  • Frank Wacker and
  • Jessica Rademacher

21 June 2021

Among patients with bronchiectasis, nontuberculous mycobacterial pulmonary disease (NTM-PD) ranged between 1 and 6% and it is suspected that its prevalence is underestimated. Our aim was to evaluate differences in computed tomography (CT) features in...

  • Article
  • Open Access
3 Citations
3,687 Views
11 Pages

Corticosteroid Resistance in Smokers—A Substudy Analysis of the CORTICO-COP Randomised Controlled Trial

  • Pradeesh Sivapalan,
  • Andras Bikov,
  • Charlotte Suppli Ulrik,
  • Therese Sophie Lapperre,
  • Alexander G. Mathioudakis,
  • Mats Christian Højberg Lassen,
  • Kristoffer Grundtvig Skaarup,
  • Tor Biering-Sørensen,
  • Jørgen Vestbo and
  • Jens-Ulrik S. Jensen

21 June 2021

The CORTICO-COP trial showed that eosinophil-guided corticosteroid-sparing treatment for acute exacerbation of chronic obstructive pulmonary disease was non-inferior to standard of care and decreased the accumulated dose of systemic corticosteroids t...

  • Article
  • Open Access
14 Citations
4,225 Views
9 Pages

21 June 2021

European evidence-based guidelines for the treatment and management of chronic pancreatitis (CP) have been made available following the harmonizing diagnosis and treatment of CP across Europe (HaPanEU) initiative by the United European Gastroenterolo...

  • Review
  • Open Access
101 Citations
12,033 Views
13 Pages

Patient-Self Inflicted Lung Injury: A Practical Review

  • Guillaume Carteaux,
  • Mélodie Parfait,
  • Margot Combet,
  • Anne-Fleur Haudebourg,
  • Samuel Tuffet and
  • Armand Mekontso Dessap

21 June 2021

Patients with severe lung injury usually have a high respiratory drive, resulting in intense inspiratory effort that may even worsen lung damage by several mechanisms gathered under the name “patient-self inflicted lung injury” (P-SILI). Even though...

  • Article
  • Open Access
10 Citations
3,291 Views
8 Pages

Hemoglobin A1c in Patients with Diabetes Predict Long-Term Mortality Following Coronary Artery Surgery

  • Muhammad Abu Tailakh,
  • Shlomo-yaron Ishay,
  • Jenan Awesat,
  • Liat Poupko,
  • Gidon Sahar and
  • Victor Novack

21 June 2021

Objective: to estimate the association between preoperative hemoglobin A1c (HbA1c) levels below and above 7%, and the rate of all-cause mortality (ACM) in diabetes mellitus (DM) patients after coronary artery bypass grafting (CABG) within a ten-year...

  • Article
  • Open Access
22 Citations
5,049 Views
7 Pages

Risk Factors of Inadequate Bowel Preparation for Screening Colonoscopy

  • Efrat L. Amitay,
  • Tobias Niedermaier,
  • Anton Gies,
  • Michael Hoffmeister and
  • Hermann Brenner

21 June 2021

The success of a colonoscopy in detecting and removing pre-cancerous and cancerous lesions depends heavily on the quality of bowel preparation. Despite efforts, 20–44% of colonoscopy participants have an inadequate bowel preparation. We aimed to asse...

  • Article
  • Open Access
16 Citations
5,162 Views
11 Pages

Rectus Femoris Mimicking Ultrasound Phantom for Muscle Mass Assessment: Design, Research, and Training Application

  • Nobuto Nakanishi,
  • Shigeaki Inoue,
  • Rie Tsutsumi,
  • Yusuke Akimoto,
  • Yuko Ono,
  • Joji Kotani,
  • Hiroshi Sakaue and
  • Jun Oto

20 June 2021

Ultrasound has become widely used as a means to measure the rectus femoris muscle in the acute and chronic phases of critical illness. Despite its noninvasiveness and accessibility, its accuracy highly depends on the skills of the technician. However...

  • Article
  • Open Access
9 Citations
5,214 Views
14 Pages

20 June 2021

Objectives: To evaluate the effect of clopidogrel vs. aspirin monotherapy on vascular function and hemostatic measurement. Background: Monotherapy with P2Y12 receptor inhibitor vs. aspirin can be a useful alterative to optimize clinical efficacy and...

  • Review
  • Open Access
22 Citations
3,866 Views
12 Pages

Sitafloxacin for Third-Line Helicobacter pylori Eradication: A Systematic Review

  • Toshihiro Nishizawa,
  • Munkhbayar Munkjargal,
  • Hirotoshi Ebinuma,
  • Osamu Toyoshima and
  • Hidekazu Suzuki

20 June 2021

Background and Aim: Sitafloxacin-based therapy is a potent candidate for third-line Helicobacter pylori eradication treatment. In this systematic review, we summarise current reports with sitafloxacin-based therapy as a third-line treatment. Methods:...

  • Review
  • Open Access
11 Citations
5,260 Views
20 Pages

20 June 2021

Total pancreatectomy is a major complex surgical procedure involving removal of the whole pancreatic parenchyma and duodenum. It leads to lifelong pancreatic exocrine and endocrine insufficiency. The control of surgery-induced diabetes (type 3) requi...

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J. Clin. Med. - ISSN 2077-0383