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Antioxidants, Volume 13, Issue 3

2024 March - 130 articles

Cover Story: Melanocyte death due to oxidative stress and autoimmune reactions causes hypopigmentation, such as vitiligo. Melanin overproduction from melanocytes stimulated by oxidative stress, hormones, or substrates causes hyperpigmentation, such as melasma. Thus, we hypothesized that certain antioxidants may help alleviate skin pigmentation disorders. This study highlights the multifaceted effects of L-cysteine, L-ascorbic acid (vitamin C), and their derivatives on melanocyte viability and melanin levels under several experimental conditions, which can guide the therapeutic application of each compound. In particular, it suggests that L-cysteine, L-cysteinamide, or L-ascorbic acid may be applied to prevent and treat skin hypopigmentation, hyperpigmentation, or both diseases in the matched order. View this paper
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Articles (130)

  • Article
  • Open Access
7 Citations
3,383 Views
17 Pages

Cyanide Insensitive Oxidase Confers Hydrogen Sulfide and Nitric Oxide Tolerance to Pseudomonas aeruginosa Aerobic Respiration

  • Martina R. Nastasi,
  • Lorenzo Caruso,
  • Francesca Giordano,
  • Marta Mellini,
  • Giordano Rampioni,
  • Alessandro Giuffrè and
  • Elena Forte

Hydrogen sulfide (H2S) and nitric oxide (NO) are long-known inhibitors of terminal oxidases in the respiratory chain. Yet, they exert pivotal signaling roles in physiological processes, and in several bacterial pathogens have been reported to confer...

  • Article
  • Open Access
6 Citations
3,589 Views
18 Pages

Protective Mechanism of Rosa roxburghii Tratt Fermentation Broth against Ultraviolet-A-Induced Photoaging of Human Embryonic Skin Fibroblasts

  • Minglu Yuan,
  • Hao Fu,
  • Qiuting Mo,
  • Shiwei Wang,
  • Changtao Wang,
  • Dongdong Wang,
  • Jiachan Zhang and
  • Meng Li

This study takes the fruit of Rosa roxburghii Tratt (RRT) as a fermentation substrate and carries out a quantitative visual analysis of the domestic and foreign literature on screenings of five different lactic acid bacteria to obtain a fermentation...

  • Article
  • Open Access
10 Citations
5,495 Views
16 Pages

Dietary Antioxidants May Support Cosmetic Treatment in Patients with Rosacea

  • Kinga Zujko-Kowalska,
  • Joanna Masłowska,
  • Małgorzata Knaś-Dawidziuk,
  • Jadwiga Hamulka and
  • Małgorzata Elżbieta Zujko

Rosacea is a chronic skin disease that significantly reduces the quality of life (QoL) of patients. The aim of this study was to assess whether dietary antioxidants can support the effect of cosmetic treatment in improving the QoL of patients with ro...

  • Article
  • Open Access
6 Citations
2,780 Views
14 Pages

Cancer immunotherapy as a promising anti-cancer strategy has been widely studied in recent years. Stigmasterol (STIG), a phytosterol, is known to have various pharmacological effects, including anti-inflammatory effects. However, the pharmacological...

  • Article
  • Open Access
2 Citations
2,288 Views
18 Pages

Long-Term Effect of Maternal Antioxidant Supplementation on the Lipid Profile of the Progeny According to the Sow’s Parity Number

  • Gerardo Gómez,
  • Hernan D. Laviano,
  • Juan García-Casco,
  • Maria Muñoz,
  • Fernando Gómez,
  • Fernando Sánchez-Esquiliche,
  • Antonio González-Bulnes,
  • Clemente López-Bote,
  • Cristina Óvilo and
  • Ana I. Rey

Pig feeding prior to the extensive fattening phase might affect the final lipid profile and product quality. This study evaluates how maternal supplementation with vitamin E (VITE) (100 mg/kg), hydroxytyrosol (HXT) (1.5 mg/kg), or combined administra...

  • Article
  • Open Access
9 Citations
3,173 Views
14 Pages

Identification and Functional Validation of Two Novel Antioxidant Peptides in Saffron

  • Yiyang Long,
  • Han Tao,
  • Shiyu Wang,
  • Bingcong Xing,
  • Zhineng Wang,
  • Kexin Liu,
  • Qingsong Shao and
  • Fei Gao

Saffron (Crocus sativus L.) is one of the most expensive spices in the world, boasting rich medicinal and edible value. However, the effective development of active natural substances in saffron is still limited. Currently, there is a lack of compreh...

  • Article
  • Open Access
16 Citations
3,116 Views
21 Pages

Bioactive Lignan Honokiol Alleviates Ovarian Oxidative Stress in Aging Laying Chickens by Regulating SIRT3/AMPK Pathway

  • Yiqiu Chen,
  • Zhaoyu Yang,
  • Jingchun Bai,
  • Xinyu Wang,
  • Qiongyu Yuan,
  • Yuling Mi and
  • Caiqiao Zhang

Aging is not only a key internal cause of age-related diseases in humans but also poses a threat to the productivity of farm animals with longer breeding cycles, such as laying chickens. Various measures were taken to prolong the laying period by red...

  • Article
  • Open Access
7 Citations
3,829 Views
18 Pages

This study explored the glucosinolate (GSL) content in Brassica plants and utilized in silico analysis approach to assess their antioxidant capabilities. GSLs, present abundantly in Brassica vegetables, offer potential health advantages, including an...

  • Systematic Review
  • Open Access
10 Citations
6,647 Views
30 Pages

Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant neurodegenerative disorder that gives rise to motor incoordination and progressive functional disabilities. Although pharmacological interventions have revealed promising prospects in the...

  • Article
  • Open Access
4 Citations
3,030 Views
17 Pages

Promoting the Aging Process and Enhancing the Production of Antioxidant Components of Garlic through Pulsed Electric Field Treatments

  • Chao-Kai Chang,
  • Sheng-Yen Tsai,
  • Ming-Shiun Tsai,
  • An-Ting Tu,
  • Chih-Yao Hou,
  • Kuan-Chen Cheng,
  • Wei-Lun Zhu,
  • Rizka Mulyani and
  • Chang-Wei Hsieh

Shortening the aging duration and enhancing the functional components of garlic present significant technical challenges that need to be addressed. Thus, this study aimed to evaluate the potential role of pulsed electric field (PEF) treatment, a nove...

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Antioxidants - ISSN 2076-3921