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Brain Sciences, Volume 11, Issue 8

August 2021 - 154 articles

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Cover Story: Visceral fat areas (VFA) might be clinically important to prevent dementia; however, the association between VFA and cognitive function in the elderly remains unknown. We aimed to evaluate the association between brain structural abnormalities using magnetic resonance imaging (MRI) and VFA and the association between cognitive function and VFA, in the elderly (N = 2364). The high-VFA group had significantly lower cognitive function and significantly higher odds ratios for white matter lesions and perivascular space than the low-VFA group. Reducing visceral fat might be important not only to prevent cardiovascular disease but also to prevent dementia. View this paper

Articles (154)

  • Article
  • Open Access
6 Citations
3,429 Views
9 Pages

PER Gene Family Polymorphisms in Relation to Cluster Headache and Circadian Rhythm in Sweden

  • Felicia Jennysdotter Olofsgård,
  • Caroline Ran,
  • Carmen Fourier,
  • Catalina Wirth,
  • Christina Sjöstrand,
  • Elisabet Waldenlind,
  • Anna Steinberg and
  • Andrea Carmine Belin

23 August 2021

The trigeminal autonomic cephalalgia, cluster headache (CH), is one of the most painful disorders known to man. One of the disorder’s most striking features is the reported diurnal rhythmicity of the attacks. For a majority of patients, the headache...

  • Article
  • Open Access
6 Citations
3,822 Views
11 Pages

Acute Regression in Down Syndrome

  • Benjamin Handen,
  • Isabel Clare,
  • Charles Laymon,
  • Melissa Petersen,
  • Shahid Zaman,
  • Sid O'Bryant,
  • Davneet Minhas,
  • Dana Tudorascu,
  • Stephanie Brown and
  • Bradley Christian

23 August 2021

Background: Acute regression has been reported in some individuals with Down syndrome (DS), typically occurring between the teenage years and mid to late 20s. Characterized by sudden, and often unexplained, reductions in language skills, functional l...

  • Article
  • Open Access
5 Citations
4,188 Views
13 Pages

Innovation in Digital Education: Lessons Learned from the Multiple Sclerosis Management Master’s Program

  • Isabel Voigt,
  • Christine Stadelmann,
  • Sven G. Meuth,
  • Richard H. W. Funk,
  • Franziska Ramisch,
  • Joachim Niemeier and
  • Tjalf Ziemssen

23 August 2021

Since 2020, the master’s program “Multiple Sclerosis Management” has been running at Dresden International University, offering structured training to become a multiple sclerosis specialist. Due to the COVID-19 pandemic, many planned teaching formats...

  • Article
  • Open Access
7 Citations
7,888 Views
14 Pages

Vestibular Stimulation May Drive Multisensory Processing: Principles for Targeted Sensorimotor Therapy (TSMT)

  • Brigitta Tele-Heri,
  • Karoly Dobos,
  • Szilvia Harsanyi,
  • Judit Palinkas,
  • Fanni Fenyosi,
  • Rudolf Gesztelyi,
  • Csaba E. More and
  • Judit Zsuga

23 August 2021

At birth, the vestibular system is fully mature, whilst higher order sensory processing is yet to develop in the full-term neonate. The current paper lays out a theoretical framework to account for the role vestibular stimulation may have driving mul...

  • Article
  • Open Access
34 Citations
8,429 Views
13 Pages

22 August 2021

Background: Despite an alarming rise in the global prevalence of dementia, the available modalities for improving cognition and mental wellbeing of dementia patients remain limited. Environmental enrichment is an experimental paradigm that has shown...

  • Article
  • Open Access
9 Citations
3,985 Views
12 Pages

Impact of Glucocorticoid on a Cellular Model of Parkinson’s Disease: Oxidative Stress and Mitochondrial Function

  • Silvia Claros,
  • Antonio Gil,
  • Mauro Martinelli,
  • Nadia Valverde,
  • Estrella Lara,
  • Federica Boraldi,
  • Jose Pavia,
  • Elisa Martín-Montañez and
  • María Garcia-Fernandez

22 August 2021

Stress seems to contribute to the neuropathology of Parkinson’s disease (PD), possibly by dysregulation of the hypothalamic–pituitary–adrenal axis. Oxidative distress and mitochondrial dysfunction are key factors involved in the pathophysiology of PD...

  • Article
  • Open Access
7 Citations
3,635 Views
16 Pages

The Effect of Light Sedation with Midazolam on Functional Connectivity of the Dorsal Attention Network

  • Junkai Wang,
  • Yachao Xu,
  • Gopikrishna Deshpande,
  • Kuncheng Li,
  • Pei Sun and
  • Peipeng Liang

22 August 2021

Altered connectivity within and between the resting-state networks (RSNs) brought about by anesthetics that induce altered consciousness remains incompletely understood. It is known that the dorsal attention network (DAN) and its anticorrelations wit...

  • Article
  • Open Access
1 Citations
3,252 Views
8 Pages

Identification of a New Mutation in RSK2, the Gene for Coffin–Lowry Syndrome (CLS), in Two Related Patients with Mild and Atypical Phenotypes

  • Mariateresa Di Stazio,
  • Stefania Bigoni,
  • Nicola Iuso,
  • Josef Vuch,
  • Rita Selvatici,
  • Sheila Ulivi and
  • Pio Adamo d’Adamo

22 August 2021

Background: Coffin–Lowry syndrome (CLS) is a syndromic form of X-linked intellectual disability, in which specific associated facial, hand, and skeletal abnormalities are diagnostic features. Methods: In the present study, an unreported missense gene...

  • Perspective
  • Open Access
10 Citations
4,006 Views
4 Pages

Gender Perspective in Dual Diagnosis

  • Marta Torrens-Melich,
  • Teresa Orengo,
  • Fernando Rodríguez de Fonseca,
  • Isabel Almodóvar,
  • Abel Baquero and
  • Ana Benito

21 August 2021

Little data are available for women diagnosed with a dual diagnosis. However, dual diagnosis in women presents increased stigma, social penalties, and barriers to access to treatment than it does for men. Indeed, it increases the probability of suffe...

  • Article
  • Open Access
5 Citations
4,085 Views
26 Pages

21 August 2021

The distribution of single Stop Signal Reaction Times (SSRT) in the stop signal task (SST) has been modelled with two general methods: a nonparametric method by Hans Colonius (1990) and a Bayesian parametric method by Dora Matzke, Gordon Logan and co...

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