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Medical Sciences, Volume 13, Issue 4

December 2025 - 122 articles

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Articles (122)

  • Editorial
  • Open Access
130 Views
5 Pages

14 December 2025

Artificial intelligence (AI) is reshaping robotic rehabilitation and shifting practice beyond pre-programmed repetitive movement patterns toward data-driven and personalised therapeutic interventions for people with neurological and musculoskeletal i...

  • Article
  • Open Access
205 Views
20 Pages

Determinants of Entero-Invasive and Non-Entero-Invasive Diarrheagenic Bacteria Among HIV-Positive and HIV-Negative Adults in Ghana

  • Hagen Frickmann,
  • Fred Stephen Sarfo,
  • Betty Roberta Norman,
  • Albert Dompreh,
  • Shadrack Osei Asibey,
  • Richard Boateng,
  • Veronica Di Cristanziano,
  • Tafese Beyene Tufa,
  • Ulrike Loderstädt and
  • Ramona Binder
  • + 4 authors

12 December 2025

Objectives: This observational and cross-sectional study investigated differential associations between entero-invasive and non-entero-invasive enteric pathogens and HIV infection, considering socioeconomic, clinical and immunological aspects. In a G...

  • Article
  • Open Access
166 Views
13 Pages

Outcome and Toxicity of Moderately Hypofractionated Post-Prostatectomy Radiotherapy: A Retrospective Study

  • Rocchina Vilella,
  • Fiorella D’Auria,
  • Luciana Valvano,
  • Barbara D’Andrea,
  • Antonietta Montagna,
  • Giovanni Castaldo,
  • Ilaria Benevento,
  • Angela Pia Solazzo,
  • Manuela Botte and
  • Grazia Lazzari
  • + 2 authors

12 December 2025

Background: In this study, we retrospectively analyzed clinical and toxicity outcomes of 67 prostate cancer (PCa) patients undergoing moderately hypofractionated radiotherapy (RT) after prostatectomy, with adjuvant or salvage intent. Methods: Irradia...

  • Article
  • Open Access
121 Views
15 Pages

Evaluation of Cell Mimics as Potential Quality Controls for Human Leukocyte Immunophenotyping

  • Louis Waeckel,
  • Brigitte Le Mauff,
  • Jacques Trauet,
  • Julie Demaret,
  • Ahmed Boumediene,
  • Margarita Hurtado-Nedelec,
  • Arnaud Ciree,
  • Gwladys Bourdenet and
  • Claude Lambert

11 December 2025

Background. Routine lymphocyte counting requires quality assurance validation using quality controls (QCs) that closely resemble fresh human blood leukocytes. This study aimed to evaluate a novel artificial product designed to mimic leukocyte light s...

  • Article
  • Open Access
147 Views
11 Pages

Echocardiographic Alterations in Subjects with Sarcopenia and Right Heart Failure

  • Arturo Orea-Tejeda,
  • Luis Aldo Delgado-Pérez,
  • Benigno Valderrábano-Salas,
  • Dulce González-Islas,
  • Álvaro Montañez-Orozco,
  • José Carlos Ruan-Díaz,
  • María José Hernández-Hernández,
  • Edgar Lozano-Hernández,
  • Carlos Patricio Chávez-Guzmán and
  • Karla García-Díaz

10 December 2025

Background: Chronic heart failure (HF) is a significant public health issue. The principal risk factors for left ventricular diastolic dysfunction (LVDD) include older age, female sex, obesity, hypertension, smoking, and diabetes, among others, all o...

  • Article
  • Open Access
366 Views
16 Pages

Montreal Cognitive Assessment (MoCA) Norms for Older Patients with a Depressive Disorder

  • Myrthe E. Scheenen,
  • Rob H. S. van den Brink,
  • Styliani Konstantinidou,
  • Astrid Lugtenburg,
  • Jasmijn Spit,
  • Gert-Jan Hendriks,
  • Paul Naarding,
  • Nathalie R. de Vent,
  • Roy P. C. Kessels and
  • Richard C. Oude Voshaar
  • + 1 author

10 December 2025

Background: Interpretation of cognitive performance in older patients with depression is challenging considering the association between late-life depression and (early-stage) neurodegenerative disease. The Montreal Cognitive Assessment (MoCA) is wid...

  • Article
  • Open Access
172 Views
11 Pages

Universal Hip Ultrasound Screening in Newborns: A 21-Month Prospective Observational Study in a Spoke Center

  • Neftj Ragusa,
  • Nefer Roberta Gianotto,
  • Virginia Deut,
  • Chiara Mattivi,
  • Francesca Compagno,
  • Marta Cherubini Scarafoni,
  • Silvia Dominici and
  • Massimo Berger

10 December 2025

Background: Developmental dysplasia of the hip (DDH) encompasses a spectrum of neonatal hip abnormalities that, if not detected and treated early, may lead to long-term orthopedic sequelae. Universal ultrasound screening using Graf’s method has...

  • Review
  • Open Access
274 Views
32 Pages

8 December 2025

PANoptosis is an integrated form of regulated cell death that combines pyroptosis, apoptosis, and necroptosis through a coordinated molecular platform known as the PANoptosome. Autophagy, in parallel, maintains immune homeostasis by controlling cellu...

  • Article
  • Open Access
196 Views
12 Pages

Cytokine Profiles and Inflammatory Implications in Chagas Disease: Associations with Ventricular Function and Conduction Disorders

  • Mario Principato,
  • Maria Victoria Carvelli,
  • Analia Gladys Paolucci,
  • Silvia Miranda,
  • Guillermo Alberto Keller,
  • Manuel Lago,
  • Guillermo Di Girolamo and
  • Justo Carbajales

8 December 2025

Background: The roles of cytokines and chemokines in the pathogenesis of Chagas cardiomyopathy (CC) have been proposed, yet their clinical significance with respect to conduction disturbances and left ventricular ejection fraction (LVEF) remains uncl...

  • Review
  • Open Access
509 Views
23 Pages

Nuclear Medicine Imaging Biomarkers in Parkinson’s Disease: Past, Present, and Future Directions

  • Anna Lisa Martini,
  • Stelvio Sestini,
  • Dinahlee Saturnino Guarino and
  • Paola Feraco

7 December 2025

Parkinson’s disease (PD) is a multifaceted neurodegenerative disorder characterized by dopaminergic neuronal loss and widespread α-synuclein pathology. Nuclear medicine imaging offers essential in vivo tools for early diagnosis, different...

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Med. Sci. - ISSN 2076-3271