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Medical Sciences, Volume 14, Issue 1

2026 March - 68 articles

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Articles (68)

  • Article
  • Open Access

Individual and Societal Economic Burden of Chronic Rhinosinusitis with or Without Nasal Polyps

  • Kjell Erik Julius Håkansson,
  • Steven Arild Wuyts Andersen,
  • Anders Løkke,
  • Ole Hilberg,
  • Rikke Ibsen,
  • Charlotte Suppli Ulrik and
  • Vibeke Backer
Med. Sci.2026, 14(1), 67;https://doi.org/10.3390/medsci14010067 
(registering DOI)

2 February 2026

Background/Objectives: Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) or without NP (CRSsNP) are common upper airway diseases with major impact on healthcare utilization. Little is known about the overall national financial burden of CRS. We...

  • Review
  • Open Access

The Role of 123I in the Management of Differentiated Thyroid Cancer: A Comprehensive Narrative Review

  • Pietro Bellini,
  • Francesco Dondi,
  • Michela Cossandi,
  • Gianluca Viganò,
  • Carlo Cappelli,
  • Elisa Gatta,
  • Davide Lombardi,
  • Riccardo Morandi,
  • Claudio Casella and
  • Francesco Bertagna
  • + 5 authors
Med. Sci.2026, 14(1), 68;https://doi.org/10.3390/medsci14010068 
(registering DOI)

2 February 2026

Differentiated thyroid carcinoma (DTC) is the most common malignant endocrine tumor, with a generally favorable prognosis. Imaging, including iodine radioactive isotope scintigraphy (IRIS), is crucial for diagnosis and follow-up. While 131I has long...

  • Article
  • Open Access
27 Views
14 Pages

Effect of Short-Term and Long-Term Non-Physiological T3 Concentrations on Cardiac Stromal Cells: From Cellular Response to In Vivo Adaptation

  • Ahmad Alhamid,
  • Yoshishige Urata,
  • Kodai Nishi,
  • Hiroshi Kurazumi,
  • Ryo Suzuki,
  • Koji Ueno,
  • Akihito Mikamo,
  • Kimikazu Hamano and
  • Tao-Sheng Li
Med. Sci.2026, 14(1), 66;https://doi.org/10.3390/medsci14010066 
(registering DOI)

31 January 2026

Background/Objectives: Epidemiological and clinical studies have linked both hypothyroidism and hyperthyroidism to adverse cardiac outcomes, including heart failure and myocardial fibrosis. Triiodothyronine (T3), a biologically active thyroid hormone...

  • Article
  • Open Access
41 Views
11 Pages

Diagnostic Accuracy of PSMA-PET/CT vs. mpMRI in Primary Staging of Intermediate- and High-Risk Prostate Cancer

  • Vanessa Talavera Cobo,
  • Carlos Andres Yánez Ruiz,
  • Mario Daniel Tapia Tapia,
  • Andres Calva Lopez,
  • Carmina Alejandra Muñoz Bastidas,
  • Francisco Javer Ancizu Marckert,
  • Marcos Torres Roca,
  • Luis Labairu Huerta,
  • Daniel Sanchez Zalabardo and
  • Bernardino Miñana-López
  • + 3 authors
Med. Sci.2026, 14(1), 64;https://doi.org/10.3390/medsci14010064 
(registering DOI)

31 January 2026

Background: Prostate-specific membrane antigen (PSMA) is markedly overexpressed in prostate cancer (PCa), and there is growing evidence to support its usefulness in initial diagnostic assessments. This study compares the diagnostic performance of PSM...

  • Article
  • Open Access
42 Views
10 Pages

Inflammatory Bowel Diseases Are Not Associated with an Increased Risk of Autoimmune Thyroiditis

  • Alexander Barton,
  • Christian Labenz,
  • Stephan Grabbe,
  • Jörn M. Schattenberg,
  • Leonard Kaps and
  • Karel Kostev
Med. Sci.2026, 14(1), 65;https://doi.org/10.3390/medsci14010065 
(registering DOI)

31 January 2026

Background/Objectives: The incidence of inflammatory bowel disease (IBD) is rising worldwide, particularly in Asia, while the highest prevalence remains in North America and Europe. Evidence on the relationship between IBD and the development of auto...

  • Article
  • Open Access
48 Views
18 Pages

Conserved Phosphoprotein Networks Identify Actionable Adhesion/Wnt and Metallothionein Modules in Cholangiocarcinoma

  • Sirinya Sitthirak,
  • Sittiruk Roytrakul,
  • Arporn Wangwiwatsin,
  • Nisana Namwat,
  • Poramate Klanrit,
  • Hasaya Dokduang,
  • Prakasit Sa-ngiamwibool,
  • Attapol Titapun,
  • Apiwat Jareanrat and
  • Watcharin Loilome
  • + 5 authors

30 January 2026

Background/Objectives: Cholangiocarcinoma (CCA) is a very aggressive biliary carcinoma characterised by significant molecular heterogeneity and restricted treatment alternatives. Despite genomic and proteomic investigations revealing recurrent change...

  • Review
  • Open Access
43 Views
22 Pages

Postoperative Pain Management Strategies Without Regional Analgesia in Knee Surgeries: A Scoping Review

  • Melissa Joo Young,
  • Kevin Heebøll Nygaard,
  • Gunhild Kjærgaard-Andersen,
  • Christina Frøslev-Friis,
  • Gayani Ranasinghe,
  • Thomas Strøm and
  • Rajesh Prabhakar Bhavsar

30 January 2026

Background/Objectives: Intensive postoperative pain is a common challenge after knee surgeries such as total knee arthroplasty, arthroscopy, cruciate ligament or meniscus repair, and fixation of tibial plateau or distal femoral fractures. This scopin...

  • Review
  • Open Access
210 Views
23 Pages

Hypoxia-Inducible Factor 1-α in Autoimmune Diseases—Insights from the Paradigm of Hashimoto’s Thyroiditis: A Narrative Review

  • Nika Srb,
  • Andrea Milostić-Srb,
  • Lea Sarić,
  • Dubravka Holik,
  • Matej Šapina,
  • Rajko Fureš,
  • Jasminka Talapko,
  • Ivana Škrlec,
  • Darko Katalinić and
  • Borna Kovačić

28 January 2026

Background/Objectives: Given the rising prevalence of autoimmune diseases and the need for new insights into the pathology of these disorders, it is important to summarize current knowledge, with an emphasis on Hashimoto’s thyroiditis (HT), sin...

  • Article
  • Open Access
116 Views
13 Pages

Alcohol Consumption Patterns and Traditional Beverages Associated with Hypertension Subtypes

  • Fiorella E. Zuzunaga-Montoya,
  • Jhosmer Ballena-Caicedo,
  • Oriana Rivera-Lozada,
  • Mario J. Valladares-Garrido,
  • Jean Pierre Eduardo Zila Velasque and
  • Víctor Juan Vera-Ponce

28 January 2026

Introduction: Alcohol consumption is a significant risk factor for hypertension (HTN), a prevalent condition that substantially affects cardiovascular health. In Peru, where various traditional alcoholic beverages exist, the relationship between alco...

  • Article
  • Open Access
140 Views
15 Pages

Predicting Difficult Tracheal Intubation in Head and Neck Cancer Patients with Osteoradionecrosis: Development of the ORN-Difficult-Airway-Score

  • Davut Deniz Uzun,
  • Tobias Gruebl,
  • Moritz Bleymehl,
  • Oliver Ristow,
  • Fabian Weykamp,
  • Thomas Held,
  • Stefan Mohr,
  • Felix C. F. Schmitt,
  • Markus A. Weigand and
  • Kristin Uzun-Lang
  • + 1 author

27 January 2026

Background: Osteoradionecrosis (ORN) following head and neck radiotherapy has been demonstrated to induce structural and functional alterations of the upper airway, with the potential to complicate the process of tracheal intubation. Despite its clin...

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Med. Sci. - ISSN 2076-3271