You are currently viewing a new version of our website. To view the old version click .

Microorganisms, Volume 13, Issue 1

January 2025 - 214 articles

Cover Story: For decades, Alzheimer’s Disease (AD) research has focused on the amyloid cascade hypothesis, which identifies amyloid-beta (Aβ) as the primary driver of the disease. However, the consistent failure of Aβ-targeted therapies to demonstrate efficacy, coupled with significant safety concerns, underscores the need to rethink our approach to AD treatment. This review explores unconventional perspectives and emerging paradigms regarding microbial involvement in AD pathogenesis, emphasizing the gut–brain axis, brain biofilms, the oral microbiome, and viral infections. We also discuss potential microbiome-based therapies, including fecal microbiota transplantation (FMT), probiotics, prebiotics, antiviral treatments, and vaccines, as promising strategies for managing and potentially preventing AD progression. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (214)

  • Article
  • Open Access
1 Citations
1,796 Views
16 Pages

As transitional ecosystems between land and sea, estuaries are characterized by a unique environment that supports complex and diverse microbial communities. A comprehensive analysis of microbial diversity and ecological processes at different trophi...

  • Article
  • Open Access
1 Citations
1,420 Views
11 Pages

Anti-Tick-Bourne Encephalitis IgM Intrathecal Synthesis as a Prediction Marker in Tick-Borne Encephalitis Patients

  • Piotr Czupryna,
  • Sambor Grygorczuk,
  • Agnieszka Siemieniako-Werszko,
  • Jakub Okrzeja,
  • Justyna Dunaj-Małyszko,
  • Justyna Adamczuk,
  • Sławomir Pancewicz,
  • Joanna Zajkowska,
  • Karolina Narejko and
  • Joanna Oklińska
  • + 2 authors

The aim of this study was to evaluate the usefulness of IgM anti-Tick-Borne Encephalitis (anti-TBE) intrathecal synthesis in the diagnosis and prediction of the clinical course of the disease. Thirty-six patients were included in the study (patients...

  • Article
  • Open Access
1,346 Views
12 Pages

NupR Is Involved in the Control of PlcR: A Pleiotropic Regulator of Extracellular Virulence Factors

  • Jiaxin Qin,
  • Ziqi Wang,
  • Cheng Qian,
  • Guohui Ji,
  • Yizhuo Zhang,
  • Zhanglei Cao,
  • Bing Yan and
  • Jun Cai

NupR is a nucleoside permease regulator belonging to the GntR family, mainly regulating nucleoside transport in Bacillus thuringiensis. A conserved binding site for NupR was found in the promoter region of plcR. This study aimed to investigate the re...

  • Article
  • Open Access
1,655 Views
15 Pages

Antibacterial Potential of Crude Extracts from Cylindrospermum alatosporum NR125682 and Loriellopsis cavernicola NR117881

  • Albert Olufemi Ikhane,
  • Foluso Oluwagbemiga Osunsanmi,
  • Rebamang Anthony Mosa and
  • Andrew Rowland Opoku

The challenges of antimicrobial resistance (AMR) to human health have pushed for the discovery of a new antibiotics agent from natural products. Cyanobacteria are oxygen-producing photosynthetic prokaryotes found in a variety of water habitats. Secon...

  • Article
  • Open Access
7 Citations
2,196 Views
19 Pages

The Isolation of Lead-Tolerant PGPR from Red Clover Soil and Its Role in Promoting the Growth of Alfalfa

  • Wanting Nie,
  • Yuchen Wu,
  • Jingwen Jiang,
  • Zicheng Wang,
  • Meiqi Mu,
  • Siwen Zhao,
  • Minghao Yang,
  • Xi Long,
  • Xiujie Yin and
  • Xiaohua Teng

Alfalfa (Medicago sativa L.) is an outstanding species used for the remediation of heavy metal-contaminated soil, and our previous research has shown that PGPR can promote plant growth under high-concentration lead stress. This discovery has forced s...

  • Article
  • Open Access
6 Citations
2,916 Views
13 Pages

Prevalence and Antibiotic Resistance of Escherichia coli Isolated from Raw Cow’s Milk

  • Roxana Ionela Drugea,
  • Mădălina Iulia Siteavu,
  • Elena Pitoiu,
  • Cristina Delcaru,
  • Ecaterina Monica Sârbu,
  • Carmen Postolache and
  • Stelian Bărăităreanu

Escherichia coli (E. coli) is one of the most common pathogens in both humans and livestock. This study aimed to investigate the prevalence of E. coli isolated from raw cow milk and evaluate its antimicrobial resistance rates. A total of 1696 mi...

  • Article
  • Open Access
5 Citations
2,328 Views
16 Pages

Comparative Genomic Analysis of Campylobacter Plasmids Identified in Food Isolates

  • Yiping He,
  • Gretchen Elizabeth Dykes,
  • Siddhartha Kanrar,
  • Yanhong Liu,
  • Nereus W. Gunther,
  • Katrina L. Counihan,
  • Joe Lee and
  • Joseph A. Capobianco

Campylobacter is one of the leading bacterial causes of gastroenteritis worldwide. It frequently contaminates poultry and other raw meat products, which are the primary sources of Campylobacter infections in humans. Plasmids, known as important mobil...

  • Article
  • Open Access
5 Citations
2,376 Views
20 Pages

Association Analysis of the Genomic and Functional Characteristics of Halotolerant Glutamicibacter endophyticus J2-5-19 from the Rhizosphere of Suaeda salsa

  • Longhao Sun,
  • Shanshan Sun,
  • Tianyang Liu,
  • Xinmin Lei,
  • Ruiqi Liu,
  • Junyi Zhang,
  • Shanshan Dai,
  • Jing Li and
  • Yanqin Ding

Halotolerant plant growth-promoting bacteria (HT-PGPB) have attracted considerable attention for their significant potential in mitigating salt stress in crops. However, the current exploration and development of HT-PGPB remain insufficient to meet t...

  • Review
  • Open Access
4 Citations
4,350 Views
14 Pages

Fungal Infections in Kidney Transplant Recipients: A Comprehensive Narrative Review

  • Maria Mazzitelli,
  • Federico Nalesso,
  • Alberto Enrico Maraolo,
  • Vincenzo Scaglione,
  • Lucrezia Furian and
  • Annamaria Cattelan

Background: Despite kidney transplantation being a life-saving procedure, patients experience a high risk of developing fungal infections (FIs), with an increased risk of both morbidity and mortality, especially during the first year after transplant...

  • Article
  • Open Access
2 Citations
2,324 Views
18 Pages

Biodegradation of Phenol at High Initial Concentration by Rhodococcus opacus 3D Strain: Biochemical and Genetic Aspects

  • Tatiana O. Anokhina,
  • Tatiana Z. Esikova,
  • Valentina N. Polivtseva,
  • Nataliya E. Suzina and
  • Inna P. Solyanikova

Phenolic compounds are an extensive group of natural and anthropogenic organic substances of the aromatic series containing one or more hydroxyl groups. The main sources of phenols entering the environment are waste from metallurgy and coke plants, e...

of 22

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Microorganisms - ISSN 2076-2607