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Microorganisms, Volume 11, Issue 3

2023 March - 277 articles

Cover Story: “This figure is Created with BioRender.com” This extensive review describes biofilm-associated bacterial infections in most body systems of husbandry animals, including fish, as well as in sport and companion animals. Biofilms are bacterial aggregates embedded in a self-produced, protective matrix. The biofilm lifestyle offers resilience to external threats such as the immune system, antimicrobials, and other treatments. It is therefore not surprising that biofilms have been observed in a number of bacterial infections. Several potential roles that biofilms can play in disease pathogenesis are also described in the review. This shows the importance of acknowledging the role of biofilms in animal bacterial infections, as the presence of biofilm influences both diagnostic procedures and treatment. View this paper
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Articles (277)

  • Article
  • Open Access
20 Citations
3,947 Views
17 Pages

Screening of Native Trichoderma Species for Nickel and Copper Bioremediation Potential Determined by FTIR and XRF

  • Gordana Racić,
  • Igor Vukelić,
  • Branko Kordić,
  • Danka Radić,
  • Milana Lazović,
  • Ljiljana Nešić and
  • Dejana Panković

Soil pollution with heavy metals is a serious threat to the environment. However, soils polluted with heavy metals are considered good sources of native metal-resistant Trichoderma strains. Trichoderma spp. are free-living fungi commonly isolated fro...

  • Article
  • Open Access
10 Citations
3,960 Views
16 Pages

The Impact of Early Life Experiences and Gut Microbiota on Neurobehavioral Development in Preterm Infants: A Longitudinal Cohort Study

  • Jie Chen,
  • Hongfei Li,
  • Tingting Zhao,
  • Kun Chen,
  • Ming-Hui Chen,
  • Zhe Sun,
  • Wanli Xu,
  • Kendra Maas,
  • Barry M. Lester and
  • Xiaomei S. Cong

Objectives: The objective of this study is to investigate the impact of early life experiences and gut microbiota on neurobehavioral development in preterm infants during neonatal intensive care unit (NICU) hospitalization. Methods: Preterm infants w...

  • Article
  • Open Access
6 Citations
7,319 Views
14 Pages

Rapid Reverse Purification DNA Extraction Approaches to Identify Microbial Pathogens in Wastewater

  • Sarah Schurig,
  • Rea Kobialka,
  • Andy Wende,
  • Md Anik Ashfaq Khan,
  • Phillip Lübcke,
  • Elias Eger,
  • Katharina Schaufler,
  • Arwid Daugschies,
  • Uwe Truyen and
  • Ahmed Abd El Wahed

Wastewater monitoring became a promising solution in the early detection of outbreaks. Despite the achievements in the identification of pathogens in wastewater using real-time PCR, there is still a lack of reliable rapid nucleic acid extraction prot...

  • Article
  • Open Access
10 Citations
4,203 Views
18 Pages

Revisiting Microbial Diversity in Hypersaline Microbial Mats from Guerrero Negro for a Better Understanding of Methanogenic Archaeal Communities

  • José Q. García-Maldonado,
  • Hever Latisnere-Barragán,
  • Alejandra Escobar-Zepeda,
  • Santiago Cadena,
  • Patricia J. Ramírez-Arenas,
  • Ricardo Vázquez-Juárez,
  • Maurilia Rojas-Contreras and
  • Alejandro López-Cortés

Knowledge regarding the diversity of methanogenic archaeal communities in hypersaline environments is limited because of the lack of efficient cultivation efforts as well as their low abundance and metabolic activities. In this study, we explored the...

  • Article
  • Open Access
13 Citations
3,210 Views
19 Pages

Histopathological, Immunohistochemical, Biochemical, and In Silico Molecular Docking Study of Fungal-Mediated Selenium Oxide Nanoparticles on Biomphalaria alexandrina (Ehrenberg, 1831) Snails

  • Amina M. Ibrahim,
  • Mahassen Ghazy,
  • Heba El-Sayed,
  • Rehab M. Abd El-Hameed,
  • Rehab G. Khalil,
  • Shereen M. Korany,
  • Abeer S. Aloufi,
  • Olfat A. Hammam and
  • Mostafa Y. Morad

Daphnia magna and freshwater snails are used as delicate bioindicators of contaminated aquatic habitats. Due to their distinctive characteristics, selenium oxide nanoparticles (SeONPs) have received interest regarding their possible implications on a...

  • Article
  • Open Access
6 Citations
2,956 Views
12 Pages

Long-Term Monitoring of Bioaerosols in an Environment without UV and Desiccation Stress, an Example from the Cave Postojnska Jama, Slovenia

  • Janez Mulec,
  • Sara Skok,
  • Rok Tomazin,
  • Jasmina Letić,
  • Tadej Pliberšek,
  • Sanja Stopinšek and
  • Saša Simčič

A natural cave environment subject to regular human visitation was selected for aerobiological study to minimize the effects of severe temperature fluctuations, UV radiation, and desiccation stress on the aerobiome. The longer sampling period of bioa...

  • Article
  • Open Access
5 Citations
3,094 Views
18 Pages

The Impact of Mineral and Energy Supplementation and Phytogenic Compounds on Rumen Microbial Diversity and Nitrogen Utilization in Grazing Beef Cattle

  • Ronyatta Weich Teobaldo,
  • Yury Tatiana Granja-Salcedo,
  • Abmael da Silva Cardoso,
  • Milena Tavares Lima Constancio,
  • Thais Ribeiro Brito,
  • Eliéder Prates Romanzini and
  • Ricardo Andrade Reis

The objective of this study was to evaluate the effect of the addition of a phytogenic compound blend (PHA) containing hydrolyzable tannins, carvacrol, and cinnamaldehyde oil to mineral salt or energy supplementation on the rumen microbiota and nitro...

  • Article
  • Open Access
12 Citations
2,815 Views
13 Pages

Silver nanoparticles (AgNPs) were biosynthesized for the first time from waste leaves extract of local doum palms in Tabuk, Saudi Arabia. The transmission electron microscope (TEM) revealed a spherical shape with a particle size from 18 to 33 nm. The...

  • Systematic Review
  • Open Access
13 Citations
7,908 Views
11 Pages

Efficacy of Fecal Microbiota Transplant on Behavioral and Gastrointestinal Symptoms in Pediatric Autism: A Systematic Review

  • Zahra Dossaji,
  • Adam Khattak,
  • Kyaw Min Tun,
  • Mark Hsu,
  • Kavita Batra and
  • Annie S. Hong

Background and Aims: There is a high prevalence of gastrointestinal-related (GI) symptoms among children with autism spectrum disorder (ASD), which is associated with the severity of behavioral symptoms. Fecal microbiota transplantation (FMT) is a pr...

  • Article
  • Open Access
59 Citations
13,046 Views
16 Pages

Nanopore sequencing is a promising technology used for 16S rRNA gene amplicon sequencing as it can provide full-length 16S reads and has a low up-front cost that allows research groups to set up their own sequencing workflows. To assess whether Nanop...

  • Article
  • Open Access
8 Citations
4,531 Views
15 Pages

16S-rRNA-Based Metagenomic Profiling of the Bacterial Communities in Traditional Bulgarian Sourdoughs

  • Vesselin Baev,
  • Elena Apostolova,
  • Velitchka Gotcheva,
  • Miglena Koprinarova,
  • Maria Papageorgiou,
  • João Miguel Rocha,
  • Galina Yahubyan and
  • Angel Angelov

Sourdoughs (SDs) are spontaneously formed microbial ecosystems composed of various species of lactic acid bacteria (LAB) and acid-tolerant yeasts in food matrices of cereal flours mixed with water. To date, more than 90 LAB species have been isolated...

  • Article
  • Open Access
12 Citations
3,516 Views
15 Pages

Promising Probiotic Properties of the Yeasts Isolated from Rabilé, a Traditionally Fermented Beer Produced in Burkina Faso

  • Iliassou Mogmenga,
  • Marius Kounbèsiounè Somda,
  • Cheik Amadou Tidiane Ouattara,
  • Ibrahim Keita,
  • Yérobessor Dabiré,
  • Camelia Filofteia Diguță,
  • Radu Cristian Toma,
  • Lewis I. Ezeogu,
  • Jerry O. Ugwuanyi and
  • Florentina Matei
  • + 1 author

In recent years, research on yeasts as probiotics has gained more and more interest, which will allow the development of “new” products in the probiotics market. In this context, seventeen yeast strains isolated from Rabilé, a trad...

  • Article
  • Open Access
4 Citations
4,264 Views
13 Pages

Six-Month Synbio® Administration Affects Nutritional and Inflammatory Parameters of Older Adults Included in the PROBIOSENIOR Project

  • Chiara Salvesi,
  • Stefania Silvi,
  • Dennis Fiorini,
  • Laura Alessandroni,
  • Gianni Sagratini,
  • Francesco Alessandro Palermo,
  • Renato De Leone,
  • Nadaniela Egidi,
  • Carlo Cifani and
  • M. Cristina Verdenelli
  • + 12 authors

The physiological changes associated with ageing contribute to the incidence of diseases, morbidity, and mortality. For modern society, it is essential to find solutions to improve elderly people’s health and quality of life. Among promising st...

  • Article
  • Open Access
1 Citations
2,698 Views
18 Pages

The balance of microbial communities in the gut is extremely important for normal physiological function. Disruption of the balance is often associated with various disorders and diseases. Both HIV infection and cocaine use are known to change the gu...

  • Article
  • Open Access
11 Citations
2,758 Views
13 Pages

Assessing Continuity of Adherence to Precautionary Measures for COVID-19 among Vaccinated People in Jazan, Saudi Arabia

  • Anwar Alameer,
  • Yahya Maslamani,
  • Ibrahim M. Gosadi,
  • Mohammed Y. Elamin,
  • Mohammed A. Muaddi,
  • Ahmad Y. Alqassim,
  • Abrar Doweri,
  • Ibrahim Namis,
  • Fatimah Busayli and
  • Abdu Dahlan
  • + 2 authors

Background: Adherence to behavioral respiratory hygiene practices is essential in preventing the transmission of COVID-19, especially given the appearance of new variants of the COVID-19 virus. This study estimated the pre- and post-vaccination level...

  • Communication
  • Open Access
3 Citations
3,951 Views
12 Pages

Genomic Analysis of the Deep-Sea Bacterium Shewanella sp. MTB7 Reveals Backgrounds Related to Its Deep-Sea Environment Adaptation

  • Sicong Li,
  • Jiahua Wang,
  • Jie Liu,
  • Hongcai Zhang,
  • Tianqiang Bao,
  • Chengwen Sun,
  • Jiasong Fang and
  • Junwei Cao

Shewanella species are widely distributed in various environments, especially deep-sea sediments, due to their remarkable ability to utilize multiple electron receptors and versatile metabolic capabilities. In this study, a novel facultatively anaero...

  • Article
  • Open Access
3,506 Views
21 Pages

Characterization of the Bacterial Microbiome in Natural Populations of Barley Stem Gall Midge, Mayetiola hordei, in Morocco

  • Imane Remmal,
  • Naima Bel Mokhtar,
  • Amal Maurady,
  • Mohammed Reda Britel,
  • Karim El Fakhouri,
  • Elias Asimakis,
  • George Tsiamis and
  • Panagiota Stathopoulou

Mayetiola hordei (Kieffer), known as barley stem gall midge, is one of the most destructive barley pests in many areas around the world, inflicting significant qualitative and quantitative damage to crop production. In this study, we investigate the...

  • Article
  • Open Access
4 Citations
2,690 Views
14 Pages

Knocking Down Gm16685 Decreases Liver Granuloma in Murine Schistosomiasis Japonica

  • Ruyu Zhao,
  • Xiaoxue Tang,
  • Huiyao Lin,
  • Chen Xing,
  • Na Xu,
  • Bingxin Dai,
  • Pingping Wang,
  • Wei Shao,
  • Miao Liu and
  • Cuiping Ren
  • + 2 authors

Long noncoding RNAs (lncRNAs) can regulate key genes and pathways in liver disease development. Moreover, macrophages are speculated to play an important role in regulating granulomatous inflammation during schistosomiasis. However, the role of lncRN...

  • Article
  • Open Access
14 Citations
6,551 Views
11 Pages

Coccidiosis in chickens is one of the major problems in the poultry industry, caused by protozoan parasites of the genus Eimeria. The current study used morphological and molecular characteristics to identify Eimeria spp. infecting domestic chickens...

  • Article
  • Open Access
18 Citations
3,582 Views
14 Pages

Mucosa-Associated Oscillospira sp. Is Related to Intestinal Stricture and Post-Operative Disease Course in Crohn’s Disease

  • Shukai Zhan,
  • Caiguang Liu,
  • Jixin Meng,
  • Ren Mao,
  • Tong Tu,
  • Jianming Lin,
  • Minhu Chen,
  • Zhirong Zeng and
  • Xiaojun Zhuang

Intestinal stricture remains one of the most intractable complications in Crohn’s disease (CD), and the involved mechanisms are poorly understood. Accumulating evidence suggests that the gut microbiota contributes to the pathogenesis of intesti...

  • Review
  • Open Access
43 Citations
7,057 Views
18 Pages

Anti-Quorum Sensing Activity of Probiotics: The Mechanism and Role in Food and Gut Health

  • Mohammed Kamal Salman,
  • Jumana Abuqwider and
  • Gianluigi Mauriello

Background: Quorum sensing (QS) is a cell-to-cell communication mechanism that occurs between inter- and intra-bacterial species and is regulated by signaling molecules called autoinducers (AIs). It has been suggested that probiotics can exert a QS i...

  • Article
  • Open Access
12 Citations
4,454 Views
22 Pages

Comparative Genomic Analysis of Virulent Vibrio (Listonella) anguillarum Serotypes Revealed Genetic Diversity and Genomic Signatures in the O-Antigen Biosynthesis Gene Cluster

  • Vimbai Irene Machimbirike,
  • Ignacio Vasquez,
  • Trung Cao,
  • Joy Chukwu-Osazuwa,
  • Oluwatoyin Onireti,
  • Cristopher Segovia,
  • Pongsak Khunrae,
  • Triwit Rattanarojpong,
  • Marije Booman and
  • Javier Santander
  • + 3 authors

Vibrio anguillarum is the most frequent pathogen affecting fish worldwide. The only known virulent strains of V. anguillarum are serotypes O1, O2, and O3. Genetic differences between the serotypes that could shed insight on the evolution and serotype...

  • Communication
  • Open Access
20 Citations
6,913 Views
11 Pages

Consumption of Bifidobacterium breve MCC1274 has been shown to improve memory and prevent brain atrophy in populations with mild cognitive impairment (MCI). Preclinical in vivo studies using Alzheimer’s disease (AD) models indicate that this pr...

  • Article
  • Open Access
7 Citations
2,598 Views
14 Pages

Fire and Rhizosphere Effects on Bacterial Co-Occurrence Patterns

  • Effimia M. Papatheodorou,
  • Spiros Papakostas and
  • George P. Stamou

Fires are common in Mediterranean soils and constitute an important driver of their evolution. Although fire effects on vegetation dynamics are widely studied, their influence on the assembly rules of soil prokaryotes in a small-scale environment has...

  • Review
  • Open Access
25 Citations
9,275 Views
17 Pages

Bone Health in People Living with HIV/AIDS: An Update of Where We Are and Potential Future Strategies

  • Musaab Ahmed,
  • Dushyant Mital,
  • Nuha Eljaili Abubaker,
  • Maria Panourgia,
  • Henry Owles,
  • Ioanna Papadaki and
  • Mohamed H. Ahmed

The developments in Human Immunodeficiency Virus (HIV) treatment and in the care of people living with HIV (PLWHIV) and Acquired Immunodeficiency Syndrome (AIDS) over the last three decades has led to a significant increase in life expectancy, on par...

  • Article
  • Open Access
11 Citations
3,180 Views
15 Pages

Growth Dynamic and Threshold Values for Spermicidal Effects of Multidrug-Resistant Bacteria in Extended Boar Semen

  • Anne-Marie Luther,
  • Christina Beckermann,
  • Thu Quynh Nguyen,
  • Jutta Verspohl and
  • Dagmar Waberski

The aim of this study was first to examine the prevalence of bacteria-associated loss of sperm quality in samples from insemination centers during a seven-year semen monitoring program and, second, to investigate the growth dynamic of four different...

  • Review
  • Open Access
8 Citations
5,559 Views
15 Pages

Challenges and Recent Advancements in COVID-19 Vaccines

  • Shao-Cheng Wang,
  • Chung-I Rai and
  • Yuan-Chuan Chen

Vaccination is the most effective method for the prevention of COVID-19 caused by SARS-CoV-2, which is still a global epidemic. However, the evolution of SARS-CoV-2 is so rapid that various variants, including the Alpha, Beta, Gamma, Delta, and Omicr...

  • Communication
  • Open Access
3 Citations
2,210 Views
8 Pages

Storage and Algal Association of Bacteria That Protect Microchloropsis salina from Grazing by Brachionus plicatilis

  • Carolyn L. Fisher,
  • Michelle V. Fong,
  • Pamela D. Lane,
  • Skylar Carlson and
  • Todd W. Lane

Loss of algal production from the crashes of algal mass cultivation systems represents a significant barrier to the economic production of microalgal-based biofuels. Current strategies for crash prevention can be too costly to apply broadly as prophy...

  • Review
  • Open Access
17 Citations
9,335 Views
13 Pages

Iron Status and Supplementation during Tuberculosis

  • Arista Nienaber,
  • Mary A. Uyoga,
  • Robin C. Dolman-Macleod and
  • Linda Malan

Tuberculosis (TB) is characterised by chronic non-resolving inflammation. The effects of the host immune and inflammatory response to reduce iron acquisition by the bacteria, together with other contributing factors, predispose TB patients to anaemia...

  • Article
  • Open Access
7 Citations
2,995 Views
16 Pages

Heterologous 1,3-Propanediol Production Using Different Recombinant Clostridium beijerinckii DSM 6423 Strains

  • Teresa Schoch,
  • Tina Baur,
  • Johanna Kunz,
  • Sophia Stöferle and
  • Peter Dürre

1,3-propanediol (1,3-PDO) is a valuable basic chemical, especially in the polymer industry to produce polytrimethylene terephthalate. Unfortunately, the production of 1,3-PDO mainly depends on petroleum products as precursors. Furthermore, the chemic...

  • Article
  • Open Access
62 Citations
11,915 Views
14 Pages

Isolation, Identification, and Characterization of Phosphate-Solubilizing Bacteria from Tunisian Soils

  • Marwa Amri,
  • Mohamed Ridha Rjeibi,
  • Marwa Gatrouni,
  • Dina M. R. Mateus,
  • Nedra Asses,
  • Henrique J. O. Pinho and
  • Chaabane Abbes

Soil microorganisms play an important role in maintaining natural ecological balance through active participation in carbon, nitrogen, sulfur, and phosphorous cycles. Phosphate-solubilizing bacteria (PSB) are of high importance in the rhizosphere, en...

  • Article
  • Open Access
7 Citations
3,031 Views
15 Pages

Utilization of Low Molecular Weight Carbon Sources by Fungi and Saprolegniales: Implications for Their Ecology and Taxonomy

  • Hossein Masigol,
  • Hans-Peter Grossart,
  • Seyedeh Roksana Taheri,
  • Reza Mostowfizadeh-Ghalamfarsa,
  • Mohammad Javad Pourmoghaddam,
  • Ali Chenari Bouket and
  • Seyed Akbar Khodaparast

Contributions of fungal and oomycete communities to freshwater carbon cycling have received increasing attention in the past years. It has been shown that fungi and oomycetes constitute key players in the organic matter cycling of freshwater ecosyste...

  • Article
  • Open Access
7 Citations
5,818 Views
15 Pages

Isolation and Characterisation of Electrogenic Bacteria from Mud Samples

  • György Schneider,
  • Dorina Pásztor,
  • Péter Szabó,
  • László Kőrösi,
  • Nandyala Siva Kishan,
  • Penmetsa Appala Rama Krishna Raju and
  • Rajnish Kaur Calay

To develop efficient microbial fuel cell systems for green energy production using different waste products, establishing characterised bacterial consortia is necessary. In this study, bacteria with electrogenic potentials were isolated from mud samp...

  • Article
  • Open Access
1 Citations
1,970 Views
17 Pages

Molecular Typing of Mastadenoviruses in Simultaneously Collected Nasopharyngeal Swabs and Stool Samples from Children Hospitalized for Acute Bronchiolitis, Acute Gastroenteritis, and Febrile Seizures

  • Urška Glinšek Biškup,
  • Andrej Steyer,
  • Lara Lusa,
  • Franc Strle,
  • Marko Pokorn,
  • Tatjana Mrvič,
  • Štefan Grosek,
  • Miroslav Petrovec and
  • Monika Jevšnik Virant

This study determines and compares the frequency of human mastadenovirus (HAdV) presence in children with acute bronchiolitis (AB), acute gastroenteritis (AGE), and febrile seizures (FS), ascertains types of HAdVs associated with each individual synd...

  • Article
  • Open Access
4 Citations
2,348 Views
13 Pages

TNFR1 Mediated Apoptosis Is Protective against Mycobacterium avium in Mice

  • Yuki Shundo,
  • Rintaro On,
  • Takemasa Matsumoto,
  • Hiroshi Ouchi and
  • Masaki Fujita

Mycobacterium avium is an intracellular proliferating pathogen that causes chronic refractory respiratory infection. Although apoptosis induced by M. avium has been reported in vitro, the role of apoptosis against M. avium infection in vivo remains u...

  • Article
  • Open Access
6 Citations
3,333 Views
30 Pages

From the Mountain to the Valley: Drivers of Groundwater Prokaryotic Communities along an Alpine River Corridor

  • Alice Retter,
  • Johannes Christoph Haas,
  • Steffen Birk,
  • Christine Stumpp,
  • Bela Hausmann,
  • Christian Griebler and
  • Clemens Karwautz

Rivers are the “tip of the iceberg”, with the underlying groundwater being the unseen freshwater majority. Microbial community composition and the dynamics of shallow groundwater ecosystems are thus crucial, due to their potential impact...

  • Systematic Review
  • Open Access
9 Citations
3,354 Views
20 Pages

Aims: Scientists have recently discovered a link between the circulating microbiome and homeostasis, as well as the pathogenesis of a number of metabolic diseases. It has been demonstrated that low-grade chronic inflammation is one of the primary mec...

  • Article
  • Open Access
14 Citations
3,196 Views
17 Pages

Colonization Ability of Bacillus subtilis NCD-2 in Different Crops and Its Effect on Rhizosphere Microorganisms

  • Weisong Zhao,
  • Yiyun Ban,
  • Zhenhe Su,
  • Shezeng Li,
  • Xiaomeng Liu,
  • Qinggang Guo and
  • Ping Ma

Bacillus subtilis strain NCD-2 is a promising biocontrol agent for soil-borne plant diseases and shows potential for promoting the growth of some crops. The purposes of this study were to analyze the colonization ability of strain NCD-2 in different...

  • Article
  • Open Access
2 Citations
2,024 Views
12 Pages

Many wild ornamental plant species have been introduced to improve the landscape of cities; however, until now, no study has been performed to explore the composition and function of foliar endophytes associated with cultivated rare plants in cities...

  • Article
  • Open Access
11 Citations
3,417 Views
13 Pages

Healthcare-Associated Bloodstream Infections Due to Multidrug-Resistant Acinetobacter baumannii in COVID-19 Intensive Care Unit: A Single-Center Retrospective Study

  • Karolina Dobrović,
  • Tea Škrobo,
  • Katarina Selec,
  • Marko Jelić,
  • Rok Čivljak,
  • Jasminka Peršec,
  • Sanja Sakan,
  • Nikolina Bušić,
  • Antonija Mihelčić and
  • Arjana Tambić Andrašević
  • + 1 author

Healthcare-associated infections are an emerging cause of morbidity and mortality in COVID-19 intensive care units (ICUs) worldwide, especially those caused by multidrug-resistant (MDR) pathogens. The objectives of this study were to assess the incid...

  • Article
  • Open Access
4 Citations
2,951 Views
17 Pages

Adaptation Strategies to High Hydrostatic Pressures in Pseudothermotoga species Revealed by Transcriptional Analyses

  • Romain Fenouil,
  • Nathalie Pradel,
  • Hassiba Belahbib,
  • Marie Roumagnac,
  • Manon Bartoli,
  • Wajdi Ben Hania,
  • Yann Denis,
  • Marc Garel,
  • Christian Tamburini and
  • Alain Dolla
  • + 3 authors

Pseudothermotoga elfii strain DSM9442 and P. elfii subsp. lettingae strain DSM14385 are hyperthermophilic bacteria. P. elfii DSM9442 is a piezophile and was isolated from a depth of over 1600 m in an oil-producing well in Africa. P. elfii subsp. lett...

  • Article
  • Open Access
4 Citations
5,713 Views
15 Pages

Necrotic enteritis (NE) is an economically important disease of chickens. We have recently shown that inflammatory responses in chickens inoculated orally with virulent Clostridium perfringens were spatially regulated. Here, we used previously virule...

  • Article
  • Open Access
19 Citations
3,381 Views
14 Pages

Polysaccharides are crucial dietary supplements and traditional pharmacological components of Ganoderma lucidum; however, the mechanisms responsible for high polysaccharide yields in G. lucidum remain unclear. Therefore, we investigated the mechanism...

  • Article
  • Open Access
8 Citations
3,326 Views
13 Pages

Oral Supplementation with Hydroxytyrosol Synthesized Using Genetically Modified Escherichia coli Strains and Essential Oils Mixture: A Pilot Study on the Safety and Biological Activity

  • Yannis V. Simos,
  • Stelios Zerikiotis,
  • Panagiotis Lekkas,
  • Antrea-Maria Athinodorou,
  • Christianna Zachariou,
  • Christina Tzima,
  • Alexandros Assariotakis,
  • Dimitrios Peschos,
  • Konstantinos Tsamis and
  • Patra Vezyraki
  • + 8 authors

Several natural compounds have been explored as immune-boosting, antioxidant and anti-inflammatory dietary supplements. Amongst them, hydroxytyrosol, a natural antioxidant found in olive products, and endemic medicinal plants have attracted the scien...

  • Article
  • Open Access
10 Citations
6,123 Views
19 Pages

Major health issues, such as the rise in oxidative stress, incidences of Alzheimer’s disease, and infections caused by antibiotic-resistant microbes, have prompted researchers to look for new therapeutics. Microbial extracts are still a good so...

  • Article
  • Open Access
7 Citations
3,199 Views
19 Pages

Methylprednisolone Promotes Mycobacterium smegmatis Survival in Macrophages through NF-κB/DUSP1 Pathway

  • Anlong Li,
  • Yonglin He,
  • Chun Yang,
  • Nan Lu,
  • Jiajia Bao,
  • Sijia Gao,
  • Felycia Fernanda Hosyanto,
  • Xintong He,
  • Huichao Fu and
  • Lei Xu
  • + 2 authors

Background: Mycobacterium tuberculosis (M. tuberculosis) is the causative agent of tuberculosis. As an important component of host immunity, macrophages are not only the first line of defense against M. tuberculosis but also the parasitic site of M. ...

  • Article
  • Open Access
14 Citations
2,754 Views
15 Pages

ntrC Contributes to Nitrogen Utilization, Stress Tolerance, and Virulence in Acidovorax citrulli

  • Dehua Liu,
  • Mei Zhao,
  • Pei Qiao,
  • Zhanhong Li,
  • Gong Chen,
  • Wei Guan,
  • Qingrong Bai,
  • Ron Walcott,
  • Yuwen Yang and
  • Tingchang Zhao

Bacterial fruit blotch (BFB), caused by Acidovorax citrulli, severely damages watermelon, melon, and other cucurbit crops worldwide. Nitrogen, one of the most important limiting elements in the environment, is necessary for the growth and reproductio...

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Microorganisms - ISSN 2076-2607