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Pathogens, Volume 13, Issue 1

January 2024 - 96 articles

Cover Story: Respiratory viruses target the human respiratory system and cause various clinical symptoms in humans. Although several host factors have been found to play a crucial role in the pathogenesis of respiratory viral infections, the interaction between respiratory viruses and the host cellular response remains poorly understood. We focused on the impact of Nrf2 activation on the replication of respiratory viruses and summarized the scientific evidence on how certain respiratory viruses dysregulate the Nrf2 activation pathway. Obtaining insights into the crosstalk between respiratory viruses and the Nrf2 pathway will set the foundation for the use of established Nrf2 activators as therapeutics for viral infections. View this paper
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Articles (96)

  • Article
  • Open Access
1 Citations
2,129 Views
15 Pages

Characterization of Variant RNAs Encapsidated during Bromovirus Infection by High-Throughput Sequencing

  • Sarah Dexheimer,
  • Nipin Shrestha,
  • Bandana Sharma Chapagain,
  • Jozef J. Bujarski and
  • Yanbin Yin

22 January 2024

Previously, we described the RNA recombinants accumulating in tissues infected with the bromoviruses BMV (Brome mosaic virus) and CCMV (Cowpea chlorotic mottle virus). In this work, we characterize the recombinants encapsidated inside the purified vi...

  • Article
  • Open Access
2 Citations
2,422 Views
13 Pages

22 January 2024

Diverse immune responses in different chicken lines can result in varying clinical consequences following avian influenza virus (AIV) infection. We compared two widely used layer breeds, Lohmann Brown (LB) and Lohmann White (LW), to examine virus rep...

  • Article
  • Open Access
1 Citations
3,277 Views
14 Pages

The Assessment of Infection Risk in Patients with Vitiligo Undergoing Dialysis for End-Stage Renal Disease: A Retrospective Cohort Study

  • Pearl Shah,
  • Mitchell Hanson,
  • Jennifer L. Waller,
  • Sarah Tran,
  • Stephanie L. Baer,
  • Varsha Taskar and
  • Wendy B. Bollag

21 January 2024

Vitiligo is an autoimmune condition that causes patchy skin depigmentation. Although the mechanism by which vitiligo induces immunocompromise is unclear, other related autoimmune diseases are known to predispose those affected to infection. Individua...

  • Review
  • Open Access
40 Citations
7,250 Views
16 Pages

The Roles and Interactions of Porphyromonas gingivalis and Fusobacterium nucleatum in Oral and Gastrointestinal Carcinogenesis: A Narrative Review

  • Bing Wang,
  • Juan Deng,
  • Valentina Donati,
  • Nabeel Merali,
  • Adam E. Frampton,
  • Elisa Giovannetti and
  • Dongmei Deng

20 January 2024

Epidemiological studies have spotlighted the intricate relationship between individual oral bacteria and tumor occurrence. Porphyromonas gingivalis and Fusobacteria nucleatum, which are known periodontal pathogens, have emerged as extensively studied...

  • Brief Report
  • Open Access
2 Citations
2,082 Views
6 Pages

Mpox Virus in the Pharynx of Men Having Sex with Men: A Case Series

  • Silvia Limonta,
  • Giuseppe Lapadula,
  • Luca Mezzadri,
  • Laura Corsico,
  • Francesca Rovida,
  • Alice Ranzani,
  • Fausto Baldanti and
  • Paolo Bonfanti

20 January 2024

The recent Mpox virus (MPV) outbreak in Europe and North America, primarily among men who have sex with men (MSM), raised concerns about various transmission sources. We examined patients with Mpox from an urban STI center in Lombardy, Italy, between...

  • Article
  • Open Access
1 Citations
2,431 Views
14 Pages

Impact of Plasmodium relictum Infection on the Colonization Resistance of Bird Gut Microbiota: A Preliminary Study

  • Justė Aželytė,
  • Apolline Maitre,
  • Lianet Abuin-Denis,
  • Elianne Piloto-Sardiñas,
  • Alejandra Wu-Chuang,
  • Rita Žiegytė,
  • Lourdes Mateos-Hernández,
  • Dasiel Obregón,
  • Alejandro Cabezas-Cruz and
  • Vaidas Palinauskas

20 January 2024

Avian malaria infection has been known to affect host microbiota, but the impact of Plasmodium infection on the colonization resistance in bird gut microbiota remains unexplored. This study investigated the dynamics of Plasmodium relictum infection i...

  • Article
  • Open Access
2 Citations
2,181 Views
15 Pages

High Genetic Diversity in Third-Generation Cephalosporin-Resistant Escherichia coli in Wastewater Systems of Schleswig-Holstein

  • Laura Carlsen,
  • Matthias Grottker,
  • Malika Heim,
  • Birte Knobling,
  • Sebastian Schlauß,
  • Kai Wellbrock and
  • Johannes K. Knobloch

20 January 2024

The spread of multidrug-resistant bacteria from humans or livestock is a critical issue. However, the epidemiology of resistant pathogens across wastewater pathways is poorly understood. Therefore, we performed a detailed comparison of third-generati...

  • Review
  • Open Access
21 Citations
9,793 Views
10 Pages

The Impact of Pathogens on Sepsis Prevalence and Outcome

  • Birte Dyck,
  • Matthias Unterberg,
  • Michael Adamzik and
  • Björn Koos

20 January 2024

Sepsis, a severe global healthcare challenge, is characterized by significant morbidity and mortality. The 2016 redefinition by the Third International Consensus Definitions Task Force emphasizes its complexity as a “life-threatening organ dysf...

  • Review
  • Open Access
6 Citations
3,306 Views
17 Pages

Antibiotic Resistance to Molecules Commonly Prescribed for the Treatment of Antibiotic-Resistant Gram-Positive Pathogens: What Is Relevant for the Clinician?

  • Gianpiero Tebano,
  • Irene Zaghi,
  • Francesco Baldasso,
  • Chiara Calgarini,
  • Roberta Capozzi,
  • Caterina Salvadori,
  • Monica Cricca and
  • Francesco Cristini

19 January 2024

Antibiotic resistance in Gram-positive pathogens is a relevant concern, particularly in the hospital setting. Several antibiotics are now available to treat these drug-resistant pathogens, such as daptomycin, dalbavancin, linezolid, tedizolid, ceftar...

  • Review
  • Open Access
13 Citations
4,481 Views
17 Pages

19 January 2024

Human T cell leukemia virus type 1 (HTLV-1) is a retrovirus associated with a lymphoproliferative disease known as adult T cell leukemia/lymphoma (ATLL). HTLV-1 infection efficiently transforms human T cells in vivo and in vitro. The virus does not t...

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Pathogens - ISSN 2076-0817