Viral Hepatitis in Europe: The Unresolved Issues
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Viral Pathogens".
Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 16664
Special Issue Editors
Interests: hepatitis viruses; HBV; viral genetic variability; antiviral resistance
Special Issues, Collections and Topics in MDPI journals
Interests: SARS-CoV-2; drug resistance; immune escape; HBV chronic infection; HBV reactivation; hepatocellular carcinoma; HIV; HDV
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Hepatitis viruses are estimated to infect between 1.6 and 3.1% of the population in Europe, with their prevalence differing markedly between western and eastern regions. The overall hepatitis morbidity and mortality rates have declined in recent decades due to universal anti-HBV vaccination programs, better surveillance systems, and new efficient therapies. However, there are still significant challenges in the management of viral hepatitis as a result of the high frequency of asymptomatic and often undiagnosed cases, high disease burden in older generations, and the rise in its incidence associated with foreign immigration.
Some of the issues in the management of HCV infection still include difficult-to-treat chronic patients, the development of vaccines and sensitive surveillance diagnostic methods for treated patients, and the availability of screening in populations at a high risk of infection and in resource-limited areas. In HBV infection, the inability to reach sterilizing cures via current therapies has developed the need for new non-invasive biomarkers capable of reflecting the intrahepatic activity of the virus. Extrahepatic manifestations and chronic infection in immunocompromised individuals have identified HEV infection as an emerging health problem, even in regions with sporadic transmission.
This Special Issue invites original research and review articles covering advancements in the diagnosis, prevention, and therapy of viral hepatitis in European countries.
Prof. Dr. Ivana Lazarevic
Dr. Valentina Svicher
Guest Editors
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Keywords
- viral hepatitis
- Europe
- HBV
- HCV
- HEV
- clinical management
- diagnostic methods
- new biomarkers
- antiviral therapy
- vaccines
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