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Pathogens, Volume 11, Issue 1

January 2022 - 109 articles

Cover Story: Helicobacter pylori is a gastric pathogen that exploits multiple host signaling pathways, leading to the disruption of key cell functions. Two bacterial virulence factors play important roles in this scenario, the vacuolating cytotoxin VacA and the translocated effector protein CagA of the cag type IV secretion system (T4SS). Specifically, by overruling the phosphorylation status of cortactin, H. pylori alternates the activity of molecular interaction partners of this important protein, thereby manipulating the performance of cytoskeletal rearrangements, endosomal trafficking, and cell movement. Here, we found that cortactin is necessary for the effective induction of T4SS- and CagA-dependent AGS cell movement and elongation but is dispensable for VacA uptake and formation of VacA-dependent vacuole formation and cell apoptosis. View this paper.
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Articles (109)

  • Review
  • Open Access
17 Citations
5,037 Views
17 Pages

Ecology of Ixodes pacificus Ticks and Associated Pathogens in the Western United States

  • Molly McVicar,
  • Isabella Rivera,
  • Jeremiah B. Reyes and
  • Monika Gulia-Nuss

13 January 2022

Lyme disease is the most important vector-borne disease in the United States and is increasing in incidence and geographic range. In the Pacific west, the western black-legged tick, Ixodes pacificus Cooley and Kohls, 1943 is an important vector of th...

  • Brief Report
  • Open Access
1 Citations
3,168 Views
7 Pages

12 January 2022

Gurltia paralysans, a metastrongyloid nematode, parasitizes in meningeal vessels in the thoracolumbar spinal cord of cats in South America and causes progressive paraparesis. Recently, the first report outside of South America described gurltiosis in...

  • Article
  • Open Access
10 Citations
2,837 Views
14 Pages

Multi-Dimensionality Immunophenotyping Analyses of MAIT Cells Expressing Th1/Th17 Cytokines and Cytotoxic Markers in Latent Tuberculosis Diabetes Comorbidity

  • Gokul Raj Kathamuthu,
  • Nathella Pavan Kumar,
  • Kadar Moideen,
  • Chandrakumar Dolla,
  • Paul Kumaran and
  • Subash Babu

12 January 2022

Mucosal-associated invariant T (MAIT) cells are innate like, and play a major role in restricting disease caused by Mycobacterium tuberculosis (Mtb) disease before the activation of antigen-specific T cells. Additionally, the potential link and syner...

  • Article
  • Open Access
37 Citations
8,106 Views
16 Pages

Biological Control of Fusarium culmorum, Fusarium graminearum and Fusarium poae by Antagonistic Yeasts

  • Izabela Podgórska-Kryszczuk,
  • Ewa Solarska and
  • Monika Kordowska-Wiater

11 January 2022

The genus Fusarium is considered to be one of the most pathogenic, phytotoxic and toxin-producing group of microorganisms in the world. Plants infected by these fungi are characterized by a reduced consumer and commercial value, mainly due to the con...

  • Article
  • Open Access
3 Citations
2,366 Views
11 Pages

Deltamethrin Application on Pre-Weaned Calves Improves Feed Consumption, Stress and Fatigue Status under Heat Stress Conditions

  • Konstantinos V. Arsenopoulos,
  • Eleftherios Triantafillou,
  • Athanasios I. Gelasakis and
  • Elias Papadopoulos

11 January 2022

Fly infestation remains a universal problem for dairy cattle herds, affecting the animals’ health and welfare status. Pre-weaned dairy calves are significantly challenged by the direct and indirect consequences of severe fly infestation, heat-s...

  • Article
  • Open Access
29 Citations
3,847 Views
11 Pages

11 January 2022

Periodontal disease (PD) is one of the most prevalent disorders globally and is strongly associated with many other diseases. Inflammatory bowel disease (IBD), an inflammatory condition of the colon and the small intestine, is reported to be associat...

  • Article
  • Open Access
6 Citations
6,280 Views
17 Pages

Ultraviolet-C Irradiation, Heat, and Storage as Potential Methods of Inactivating SARS-CoV-2 and Bacterial Pathogens on Filtering Facepiece Respirators

  • Rhodri Harfoot,
  • Deborah B. Y. Yung,
  • William A. Anderson,
  • Cervantée E. K. Wild,
  • Nicolene Coetzee,
  • Leonor C. Hernández,
  • Blair Lawley,
  • Daniel Pletzer,
  • José G. B. Derraik and
  • Yvonne C. Anderson
  • + 1 author

10 January 2022

The arrival of SARS-CoV-2 to Aotearoa/New Zealand in February 2020 triggered a massive response at multiple levels. Procurement and sustainability of medical supplies to hospitals and clinics during the then upcoming COVID-19 pandemic was one of the...

  • Article
  • Open Access
4 Citations
3,286 Views
17 Pages

10 January 2022

Symbiotic microorganisms in the intestinal tract can influence the general fitness of their hosts and contribute to protecting them against invading pathogens. In this study, we obtained isolate Phytobacter diazotrophicus SCO41 from the gut of free-l...

  • Case Report
  • Open Access
6 Citations
3,008 Views
9 Pages

Xanthogranulomatous Pyelonephritis Caused by Stenotrophomonas maltophilia—The First Case Report and Brief Review

  • Răzvan-Cosmin Petca,
  • Răzvan-Alexandru Dănău,
  • Răzvan-Ionuț Popescu,
  • Daniel Damian,
  • Cristian Mareș,
  • Aida Petca and
  • Viorel Jinga

10 January 2022

Xanthogranulomatous pyelonephritis (XGP) represents a rare and severe pathology secondary to chronic urinary obstruction and recurrent infections. Commonly, this condition leads to loss of kidney function, and frequently, surgical approach is the onl...

  • Review
  • Open Access
23 Citations
9,155 Views
9 Pages

Some patients with chronic rhinitis have a positive nasal allergen provocation test (NAPT) without systemic IgE sensitization by skin prick tests or serum allergen-specific IgE (sIgE). This novel concept is called local allergic rhinitis (LAR) and af...

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Pathogens - ISSN 2076-0817Creative Common CC BY license