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Journal of Personalized Medicine, Volume 11, Issue 3

March 2021 - 80 articles

Cover Story: Ideal cardiovascular health is determined by a composite of health factors (weight, blood pressure, blood sugar, and blood cholesterol) and health behaviors (avoiding tobacco, healthy diet, exercise). Digital health devices, including activity and step trackers, scales, and other devices, have become mainstream and are capable of measuring many of the health factors and behaviors that comprise ideal cardiovascular health. The aim of the current study was to compare participant self-reported data with objective weight and activity data recorded by digital health devices. The finding that incorporated objective digital health device data into an assessment of ideal cardiovascular health impacts the overall health score has implications for future studies of cardiovascular health and disease. View this paper
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Articles (80)

  • Article
  • Open Access
6 Citations
3,409 Views
15 Pages

A Comparative in Silico Analysis of CD24’s Prognostic Value in Human and Canine Prostate Cancer

  • Antonio Fernando Leis-Filho,
  • Patrícia de Faria Lainetti,
  • Mayara Simão Franzoni,
  • Chiara Palmieri,
  • Priscila Emiko Kobayshi,
  • Renee Laufer-Amorim and
  • Carlos Eduardo Fonseca-Alves

23 March 2021

CD24 is a cell surface molecule anchored by glycosyl-phosphatidyl-inositol and expressed by different human cancers, including prostate cancer (PC). Some studies have demonstrated that CD24 expression is associated with poor patient outcome; however,...

  • Article
  • Open Access
31 Citations
7,414 Views
18 Pages

Salivary Biomarkers for Dental Caries Detection and Personalized Monitoring

  • Pune N. Paqué,
  • Christopher Herz,
  • Daniel B. Wiedemeier,
  • Konstantinos Mitsakakis,
  • Thomas Attin,
  • Kai Bao,
  • Georgios N. Belibasakis,
  • John P. Hays,
  • Joël S. Jenzer and
  • Wendy E. Kaman
  • + 7 authors

23 March 2021

This study investigated the potential of salivary bacterial and protein markers for evaluating the disease status in healthy individuals or patients with gingivitis or caries. Saliva samples from caries- and gingivitis-free individuals (n = 18), pati...

  • Review
  • Open Access
33 Citations
5,042 Views
13 Pages

A Review on the Value of Imaging in Differentiating between Large Vessel Vasculitis and Atherosclerosis

  • Pieter H. Nienhuis,
  • Gijs D. van Praagh,
  • Andor W. J. M. Glaudemans,
  • Elisabeth Brouwer and
  • Riemer H. J. A. Slart

23 March 2021

Imaging is becoming increasingly important for the diagnosis of large vessel vasculitis (LVV). Atherosclerosis may be difficult to distinguish from LVV on imaging as both are inflammatory conditions of the arterial wall. Differentiating atheroscleros...

  • Review
  • Open Access
80 Citations
8,101 Views
17 Pages

Liquid Biopsy Biomarkers in Urine: A Route towards Molecular Diagnosis and Personalized Medicine of Bladder Cancer

  • Matteo Ferro,
  • Evelina La Civita,
  • Antonietta Liotti,
  • Michele Cennamo,
  • Fabiana Tortora,
  • Carlo Buonerba,
  • Felice Crocetto,
  • Giuseppe Lucarelli,
  • Gian Maria Busetto and
  • Francesco Del Giudice
  • + 5 authors

23 March 2021

Bladder cancer (BC) is characterized by high incidence and recurrence rates together with genomic instability and elevated mutation degree. Currently, cystoscopy combined with cytology is routinely used for diagnosis, prognosis and disease surveillan...

  • Article
  • Open Access
18 Citations
3,738 Views
11 Pages

Gut Microbiota and Non-Alcoholic Fatty Liver Disease Severity in Type 2 Diabetes Patients

  • Hui-Ju Tsai,
  • Yi-Chun Tsai,
  • Wei-Wen Hung,
  • Wei-Chun Hung,
  • Chen-Chia Chang and
  • Chia-Yen Dai

23 March 2021

Introduction: Non-alcoholic fatty liver disease (NAFLD) remains an important health issue worldwide. The increasing prevalence of NAFLD is linked to type 2 diabetes (T2D). The gut microbiota is associated with the development of NAFLD and T2D. Howeve...

  • Article
  • Open Access
6 Citations
2,977 Views
12 Pages

Tumor Infiltrating Neutrophils Are Frequently Found in Adenocarcinomas of the Biliary Tract and Their Precursor Lesions with Possible Impact on Prognosis

  • Vittorio Branchi,
  • Benedict Jürgensen,
  • Laura Esser,
  • Maria Gonzalez-Carmona,
  • Tobias J. Weismüller,
  • Christian P. Strassburg,
  • Jonas Henn,
  • Alexander Semaan,
  • Philipp Lingohr and
  • Steffen Manekeller
  • + 4 authors

23 March 2021

Biliary tract cancer (BTC) is characterized by an intense stromal reaction and a complex landscape of infiltrating immune cells. Evidence is emerging that tumor-infiltrating neutrophils (TINs) have an impact on carcinogenesis and tumor progression. T...

  • Article
  • Open Access
6 Citations
3,209 Views
24 Pages

23 March 2021

Poor study reproducibility is a concern in translational research. As a solution, it is recommended to increase sample size (N), i.e., add more subjects to experiments. The goal of this study was to examine/visualize data multimodality (data with >...

  • Review
  • Open Access
29 Citations
4,564 Views
15 Pages

Histone Deacetylase Inhibitors in the Treatment of Hepatocellular Carcinoma: Current Evidence and Future Opportunities

  • Nikolaos Garmpis,
  • Christos Damaskos,
  • Anna Garmpi,
  • Vasiliki E. Georgakopoulou,
  • Panagiotis Sarantis,
  • Efstathios A. Antoniou,
  • Michalis V. Karamouzis,
  • Afroditi Nonni,
  • Dimitrios Schizas and
  • Evangelos Diamantis
  • + 7 authors

22 March 2021

Hepatocellular carcinoma (HCC) remains a major health problem worldwide with a continuous increasing prevalence. Despite the introduction of targeted therapies like the multi-kinase inhibitor sorafenib, treatment outcomes are not encouraging. The pro...

  • Article
  • Open Access
22 Citations
4,384 Views
12 Pages

Elevated Monocyte to Lymphocyte Ratio and Increased Mortality among Patients with Chronic Kidney Disease Hospitalized for COVID-19

  • Ramsés Dávila-Collado,
  • Oscar Jarquín-Durán,
  • Andrés Solís-Vallejo,
  • Mai Anh Nguyen and
  • J. Luis Espinoza

22 March 2021

Chronic kidney disease (CKD) constitutes a major health problem and one of the leading causes of death worldwide. Patients with CKD have impaired immune functions that predispose them to an increased risk of infections, as well as virus-associated ca...

  • Article
  • Open Access
31 Citations
3,927 Views
10 Pages

Alterations of Left Ventricular Function Persisting during Post-Acute COVID-19 in Subjects without Previously Diagnosed Cardiovascular Pathology

  • Mariana Tudoran,
  • Cristina Tudoran,
  • Voichita Elena Lazureanu,
  • Adelina Raluca Marinescu,
  • Gheorghe Nicusor Pop,
  • Alexandru Silvius Pescariu,
  • Alexandra Enache and
  • Talida Georgiana Cut

22 March 2021

(1) Background: Coronavirus infection (Covid-19) has emerged as a severe medical condition, associated with high pulmonary morbidity and often with cardiovascular (CV) complications. This study aims to evidence the persistence of left ventricular (LV...

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J. Pers. Med. - ISSN 2075-4426Creative Common CC BY license