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Diagnostics, Volume 7, Issue 4

December 2017 - 8 articles

Cover Story: Biochemical recurrence following curative treatment for prostate cancer is a common problem. Multiple imaging modalities can be used to determine the exact location of this relapse. Comparison of 18F-choline PET-CT and axial MRI shows that MRI is an interesting screening tool for the detection of bone metastases because of its low probability of false negative results. However, F-18 choline PET is a valuable addition, as it can overrule false positive MRI results and detect non-axial metastases. View this paper
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Articles (8)

  • Interesting Images
  • Open Access
1 Citations
6,621 Views
5 Pages
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Functional Imaging with 18F-FDG PET/CT and Diffusion Weighted Imaging (DWI) in Early Response Evaluation of Combination Therapy of Elotuzumab, Lenalidomide, and Dexamethasone in a Relapsed Multiple Myeloma Patient

  • Christos Sachpekidis,
  • Antonia Dimitrakopoulou-Strauss,
  • Stefan Delorme and
  • Hartmut Goldschmidt
Diagnostics2017, 7(4), 61;https://doi.org/10.3390/diagnostics7040061

15 December 2017

Elotuzumab is the first monoclonal antibody approved for the treatment of relapsed-refractory multiple myeloma (MM) in combination with lenalidomide, an immunodulatory drug, and dexamethasone. We report on a multiply pre-treated MM patient with disea...

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  • Case Report
  • Open Access
4 Citations
6,405 Views
4 Pages
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Avid 18F-FDG Uptake in Idiopathic Tumoral Calcinosis Mimicking Lymph Node Metastasis

  • Jesper Strandberg and
  • Helle D. Zacho
Diagnostics2017, 7(4), 60;https://doi.org/10.3390/diagnostics7040060

13 December 2017

Tumoral calcinosis is a benign condition characterized by periarticular calcified lesions that is frequently observed in patients with chronic renal failure. Tumoral calcinosis often presents with subcutaneous masses and joint swelling. We present a...

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  • Interesting Images
  • Open Access
3 Citations
7,188 Views
3 Pages
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Staphylococcus aureus Bacteremia from Diffuse Muscular Infection Following Acupuncture Visualized by 18F-FDG PET/CT and MRI

  • Andreas Knudsen,
  • Carsten Thomsen and
  • Lothar Wiese
Diagnostics2017, 7(4), 59;https://doi.org/10.3390/diagnostics7040059

30 November 2017

We describe the clinical course of a 60-year old male admitted with Staphylococcus aureus bacteremia and back-pain. The patient was suspected of having spondylitis and treated as such with antibiotics; however, both fluorine-18 fluoro-2-deoxy-d-gluco...

Full Article
  • Review
  • Open Access
64 Citations
14,877 Views
14 Pages
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Improving the Accessibility and Efficiency of Point-of-Care Diagnostics Services in Low- and Middle-Income Countries: Lean and Agile Supply Chain Management

  • Desmond Kuupiel,
  • Vitalis Bawontuo and
  • Tivani P. Mashamba-Thompson
Diagnostics2017, 7(4), 58;https://doi.org/10.3390/diagnostics7040058

29 November 2017

Access to point-of-care (POC) diagnostics services is essential for ensuring rapid disease diagnosis, management, control, and surveillance. POC testing services can improve access to healthcare especially where healthcare infrastructure is weak and...

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  • Article
  • Open Access
15 Citations
11,637 Views
9 Pages
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A Score-Based Approach to 18F-FDG PET Images as a Tool to Describe Metabolic Predictors of Myocardial Doxorubicin Susceptibility

  • Matteo Bauckneht,
  • Silvia Morbelli,
  • Francesco Fiz,
  • Giulia Ferrarazzo,
  • Roberta Piva,
  • Alberto Nieri,
  • Matteo Sarocchi,
  • Paolo Spallarossa,
  • Maria Elisa Canepari and
  • Eleonora Arboscello
  • + 6 authors
Diagnostics2017, 7(4), 57;https://doi.org/10.3390/diagnostics7040057

26 October 2017

Purpose: To verify the capability of 18F-fluorodeoxy-glucose positron emission tomography/computed tomography (FDG-PET/CT) to identify patients at higher risk of developing doxorubicin (DXR)-induced cardiotoxicity, using a score-based image approach....

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  • Concept Paper
  • Open Access
41 Citations
6,705 Views
6 Pages
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Implementing a Multidisciplinary Tumor Board in the Community Practice Setting

  • Michele Lesslie and
  • Jay R. Parikh
Diagnostics2017, 7(4), 55;https://doi.org/10.3390/diagnostics7040055

17 October 2017

Multidisciplinary tumor boards are an opportunity for radiologists to demonstrate value to referring clinicians, the hospital, and patients. Multidisciplinary tumor boards are commonly utilized in academic institutions, but may not be readily availab...

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  • Article
  • Open Access
10 Citations
8,941 Views
6 Pages
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Prospective Comparison of F-18 Choline PET/CT Scan Versus Axial MRI for Detecting Bone Metastasis in Biochemically Relapsed Prostate Cancer Patients

  • Wouter Huysse,
  • Frédéric Lecouvet,
  • Paolo Castellucci,
  • Piet Ost,
  • Valerie Lambrecht,
  • Carlos Artigas,
  • Marie-Laurence Denis,
  • Kathia De Man,
  • Louke Delrue and
  • Lennart Jans
  • + 6 authors
Diagnostics2017, 7(4), 56;https://doi.org/10.3390/diagnostics7040056

17 October 2017

We compared fluor-18 choline positron emission tomography/computed tomography (PET/CT) and axial skeleton magnetic resonance imaging (MRI) prospectively obtained for the detection of bone metastases in non-castrated patients with biochemically recurr...

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  • Review
  • Open Access
30 Citations
13,851 Views
33 Pages
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Single Domain Antibodies as New Biomarker Detectors

  • Chiuan Herng Leow,
  • Katja Fischer,
  • Chiuan Yee Leow,
  • Qin Cheng,
  • Candy Chuah and
  • James McCarthy
Diagnostics2017, 7(4), 52;https://doi.org/10.3390/diagnostics7040052

17 October 2017

Biomarkers are defined as indicators of biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention. Biomarkers have been widely used for early detection, prediction of response after treatment, and for moni...

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Diagnostics - ISSN 2075-4418
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