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Diagnostics, Volume 11, Issue 12

December 2021 - 237 articles

Cover Story: Osteochondritis dissecans of the elbow (OCD) is a rare intra-articular osteochondral lesion that is associated with overhead throwing sports. At present, no single imaging modality can adequately predict lesion severity, and therefore, surgery is the only means of conclusively confirming the severity of OCD lesions. To address this difficulty, we developed a method to create 3D MRI-CT fusion images (MCFIs) of OCD lesions. This computer-aided technique combines the advantages of CT and MRI and provides a minimally invasive, accurate preoperative evaluation of OCD lesions. In addition, detailed surgical simulation is possible, which could aid surgeons in intraoperative decision making. In this article, we introduce the use and clinical applicability of MCFIs as a method of OCD lesion evaluation and surgical simulation for OCD lesions. View this paper.
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Articles (237)

  • Review
  • Open Access
112 Citations
14,606 Views
15 Pages

Updates of Risk Factors for Anastomotic Leakage after Colorectal Surgery

  • Eugenia Claudia Zarnescu,
  • Narcis Octavian Zarnescu and
  • Radu Costea

17 December 2021

Anastomotic leakage is a potentially severe complication occurring after colorectal surgery and can lead to increased morbidity and mortality, permanent stoma formation, and cancer recurrence. Multiple risk factors for anastomotic leak have been iden...

  • Article
  • Open Access
23 Citations
4,137 Views
15 Pages

17 December 2021

Radiogenomic and radiotranscriptomic studies have the potential to pave the way for a holistic decision support system built on genomics, transcriptomics, radiomics, deep features and clinical parameters to assess treatment evaluation and care planni...

  • Review
  • Open Access
12 Citations
3,891 Views
13 Pages

Lung Ultrasound: A Diagnostic Leading Tool for SARS-CoV-2 Pneumonia: A Narrative Review

  • Luigi Maggi,
  • Anna Maria Biava,
  • Silvia Fiorelli,
  • Flaminia Coluzzi,
  • Alberto Ricci and
  • Monica Rocco

17 December 2021

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide causing a global pandemic. In this context, lung ultrasound (LUS) has played an important role due to its high diagnostic sensitivity, low costs, simplicity of executio...

  • Article
  • Open Access
3 Citations
3,375 Views
14 Pages

Diplopia Is Frequent and Associated with Motor and Non-Motor Severity in Parkinson’s Disease: Results from the COPPADIS Cohort at 2-Year Follow-Up

  • Diego Santos García,
  • Lucía Naya Ríos,
  • Teresa de Deus Fonticoba,
  • Carlos Cores Bartolomé,
  • Lucía García Roca,
  • Maria Feal Painceiras,
  • Cristina Martínez Miró,
  • Hector Canfield,
  • Silvia Jesús and
  • Miquel Aguilar
  • + 40 authors

17 December 2021

Background and objective: Diplopia is relatively common in Parkinson’s disease (PD) but is still understudied. Our aim was to analyze the frequency of diplopia in PD patients from a multicenter Spanish cohort, to compare the frequency with a co...

  • Article
  • Open Access
15 Citations
3,755 Views
12 Pages

18F-Fluorocholine PET and 4D-CT in Patients with Persistent and Recurrent Primary Hyperparathyroidism

  • Adrien Latge,
  • Sophie Riehm,
  • Michel Vix,
  • Jacob Bani,
  • Mihaela Ignat,
  • Valentin Pretet,
  • Mehdi Helali,
  • Giorgio Treglia and
  • Alessio Imperiale

17 December 2021

Patients with primary hyperparathyroidism (pHPT) can develop persistent (P-pHPT) or recurrent (R-pHPT) disease after parathyroidectomy. Before recommending reoperation, recurrence must be accurately identified because of the high risk of complication...

  • Article
  • Open Access
7 Citations
3,496 Views
13 Pages

Effects of Multi-Shell Free Water Correction on Glioma Characterization

  • Lea Starck,
  • Fulvio Zaccagna,
  • Ofer Pasternak,
  • Ferdia A. Gallagher,
  • Renate Grüner and
  • Frank Riemer

17 December 2021

Diffusion MRI is a useful tool to investigate the microstructure of brain tumors. However, the presence of fast diffusing isotropic signals originating from non-restricted edematous fluids, within and surrounding tumors, may obscure estimation of the...

  • Review
  • Open Access
6 Citations
5,253 Views
11 Pages

Forensic Value of Genetic Variants Associated with Anti-Social Behavior

  • Antonio Oliva,
  • Simone Grassi,
  • Massimo Zedda,
  • Marco Molinari and
  • Stefano Ferracuti

17 December 2021

Insanity defense is sometimes invoked in criminal cases, and its demonstration is usually based on a multifactorial contribution of behavioural, clinical, and neurological elements. Neuroradiological evidence of structural alterations in cerebral are...

  • Article
  • Open Access
4 Citations
3,064 Views
9 Pages

Clinical Evaluation of an Abbreviated Contrast-Enhanced Whole-Body MRI for Oncologic Follow-Up Imaging

  • Judith Herrmann,
  • Saif Afat,
  • Andreas Brendlin,
  • Maryanna Chaika,
  • Andreas Lingg and
  • Ahmed E. Othman

16 December 2021

Over the last decades, overall survival for most cancer types has increased due to earlier diagnosis and more effective treatments. Simultaneously, whole-body MRI-(WB-MRI) has gained importance as a radiation free staging alternative to computed tomo...

  • Article
  • Open Access
9 Citations
2,788 Views
17 Pages

Does the Urinary Proteome Reflect ccRCC Stage and Grade Progression?

  • Lucia Santorelli,
  • Martina Stella,
  • Clizia Chinello,
  • Giulia Capitoli,
  • Isabella Piga,
  • Andrew Smith,
  • Angelica Grasso,
  • Marco Grasso,
  • Giorgio Bovo and
  • Fulvio Magni

16 December 2021

Due its ability to provide a global snapshot of kidney physiology, urine has emerged as a highly promising, non-invasive source in the search for new molecular indicators of disease diagnosis, prognosis, and surveillance. In particular, proteomics re...

  • Review
  • Open Access
9 Citations
5,125 Views
28 Pages

Expression of Immune Checkpoints in Malignant Tumors: Therapy Targets and Biomarkers for the Gastric Cancer Prognosis

  • Danzan Mansorunov,
  • Natalya Apanovich,
  • Pavel Apanovich,
  • Fatimat Kipkeeva,
  • Tatyana Muzaffarova,
  • Anna Kuzevanova,
  • Maxim Nikulin,
  • Olga Malikhova and
  • Alexander Karpukhin

16 December 2021

To increase the effectiveness of anticancer therapy based on immune checkpoint (IC) inhibition, some ICs are being investigated in addition to those used in clinic. We reviewed data on the relationship between PD-L1, B7-H3, B7-H4, IDO1, Galectin-3 an...

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Diagnostics - ISSN 2075-4418