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Life, Volume 10, Issue 11

2020 November - 57 articles

Cover Story: Type IV pili (T4P) are cell-surface proteinaceous filaments found in many prokaryotic organisms and convey twitching motility through their extension/retraction cycles, moving cells across surfaces. In cyanobacteria, twitching motility is the sole mode of motility characterised to date and is how cells perform phototaxis, the movement towards and away from directional light sources. Wavelength and intensity of light determine the direction of movement and signal for some cyanobacteria to form multicellular assemblages. Formation of such aggregates allows for acclimation to unfavourable environmental conditions and stresses. T4P also enable natural transformation and secretion processes. Thus, cyanobacteria respond to external stimuli by escaping unfavourable environmental conditions via phototaxis, exchanging genetic material, or modifying their surroundings to better fit their needs. View this paper
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Articles (57)

  • Case Report
  • Open Access
16 Citations
3,105 Views
9 Pages

Long-Term SARS-CoV-2 Infection Associated with Viral Dissemination in Different Body Fluids Including Bile in Two Patients with Acute Cholecystitis

  • Rossana Scutari,
  • Lorenzo Piermatteo,
  • Matteo Ciancio Manuelli,
  • Marco Iannetta,
  • Romina Salpini,
  • Ada Bertoli,
  • Claudia Alteri,
  • Patrizia Saccomandi,
  • Maria Concetta Bellocchi and
  • Francesca Ceccherini-Silberstein
  • + 8 authors

23 November 2020

Our study aimed to investigate the kinetics of SARS-CoV-2 RNA in bile and in different body fluids of two SARS-CoV-2 positive patients with acute cholecystitis by innovative droplet digital PCR (ddPCR) assays. For each patient, nasopharyngeal- and re...

  • Article
  • Open Access
18 Citations
5,710 Views
14 Pages

Effect of Acetaminophen (APAP) on Physiological Indicators in Lactuca sativa

  • Jiri Kudrna,
  • Frantisek Hnilicka,
  • Jan Kubes,
  • Pavla Vachova,
  • Helena Hnilickova and
  • Margita Kuklova

23 November 2020

This study analyzes the effects of acetaminophen (APAP) as a contaminant on physiological characteristics of lettuce plants (Lactuca sativa L.). Experiments were provided in an experimental greenhouse with semi-controlled conditions. The effect of di...

  • Review
  • Open Access
12 Citations
5,894 Views
42 Pages

23 November 2020

The ease with which the unicellular yeast Saccharomyces cerevisiae can be manipulated genetically and biochemically has established this organism as a good model for the study of human mitochondrial diseases. The combined use of biochemical and molec...

  • Article
  • Open Access
10 Citations
3,472 Views
14 Pages

Prognostic Role of FGFR3 Expression Status and Tumor-Related MicroRNAs Level in Association with PD-L1 Expression in Primary Luminal Non-Muscular Invasive Bladder Carcinoma

  • Ekaterina Blinova,
  • Anton Buzdin,
  • Dmitry Enikeev,
  • Dmitry Roshchin,
  • Maria Suntsova,
  • Elena Samyshina,
  • Aleksey Drobyshev,
  • Olga Deryabina,
  • Tatiana Demura and
  • Dmitrij Perepechin
  • + 11 authors

23 November 2020

Background: bladder cancer is one of the most common urinary tract malignancies. Establishment of robust predictors of disease progression and outcome is important for personalizing treatment of non-muscular invasive bladder carcinoma (NMIBC). In thi...

  • Article
  • Open Access
15 Citations
3,615 Views
16 Pages

Red Blood Cell Distribution Width Is Associated with Deterioration of Renal Function and Cardiovascular Morbidity and Mortality in Patients with Diabetic Kidney Disease

  • Stefanos Roumeliotis,
  • Aikaterini Stamou,
  • Athanasios Roumeliotis,
  • Marios Theodoridis,
  • Konstantinos Leivaditis,
  • Stylianos Panagoutsos and
  • Vassilios Liakopoulos

22 November 2020

We sought to investigate the possible association between Red Blood Cell Distribution Width (RDW), vascular calcification, oxidative stress and renal function and all-cause/cardiovascular (CV) mortality, CV events and progression of kidney disease in...

  • Article
  • Open Access
11 Citations
3,594 Views
26 Pages

Regulatory Potential of Long Non-Coding RNAs (lncRNAs) in Boar Spermatozoa with Good and Poor Freezability

  • Leyland Fraser,
  • Łukasz Paukszto,
  • Anna Mańkowska,
  • Paweł Brym,
  • Przemysław Gilun,
  • Jan P. Jastrzębski,
  • Chandra S. Pareek,
  • Dibyendu Kumar and
  • Mariusz Pierzchała

21 November 2020

Long non-coding RNAs (lncRNAs) are suggested to play an important role in the sperm biological processes. We performed de novo transcriptome assembly to characterize lncRNAs in spermatozoa, and to investigate the role of the potential target genes of...

  • Review
  • Open Access
32 Citations
6,934 Views
20 Pages

21 November 2020

Microorganisms are effective platforms for the production of a variety of chemicals including biofuels, commodity chemicals, polymers and other natural products. However, deep cellular understanding is required for improvement of current biofuel cell...

  • Article
  • Open Access
19 Citations
3,178 Views
14 Pages

Mouthguard Use Effect on the Biomechanical Response of an Ankylosed Maxillary Central Incisor during a Traumatic Impact: A 3-Dimensional Finite Element Analysis

  • Alexandre Luiz Souto Borges,
  • Amanda Maria de Oliveira Dal Piva,
  • Laís Regiane da Silva Concílio,
  • Tarcisio José de Arruda Paes-Junior and
  • João Paulo Mendes Tribst

20 November 2020

(1) Background: Trauma is a very common experience in contact sports; however, there is an absence of data regarding the effect of athletes wearing mouthguards (MG) associated with ankylosed maxillary central incisor during a traumatic impact. (2) Me...

  • Review
  • Open Access
41 Citations
9,263 Views
21 Pages

Genome Editing by CRISPR-Cas: A Game Change in the Genetic Manipulation of Chlamydomonas

  • Manel Ghribi,
  • Serge Basile Nouemssi,
  • Fatma Meddeb-Mouelhi and
  • Isabel Desgagné-Penix

20 November 2020

Microalgae are promising photosynthetic unicellular eukaryotes among the most abundant on the planet and are considered as alternative sustainable resources for various industrial applications. Chlamydomonas is an emerging model for microalgae to be...

  • Review
  • Open Access
12 Citations
7,321 Views
35 Pages

Analysis of Human Mutations in the Supernumerary Subunits of Complex I

  • Quynh-Chi L. Dang,
  • Duong H. Phan,
  • Abigail N. Johnson,
  • Mukund Pasapuleti,
  • Hind A. Alkhaldi,
  • Fang Zhang and
  • Steven B. Vik

20 November 2020

Complex I is the largest member of the electron transport chain in human mitochondria. It comprises 45 subunits and requires at least 15 assembly factors. The subunits can be divided into 14 “core” subunits that carry out oxidation–...

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Life - ISSN 2075-1729