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Micromachines 2016, 7(5), 89;

A Rapid Micromixer for Centrifugal Microfluidic Platforms

Department of Mechanical and Industrial Engineering, Louisiana State University, Baton Rouge, LA 70803, USA
College of Mechanical Engineering, Xi’an Jiaotong University, Xi’an 710049, China
Author to whom correspondence should be addressed.
Academic Editor: Marc Madou
Received: 6 January 2016 / Revised: 9 April 2016 / Accepted: 26 April 2016 / Published: 10 May 2016
(This article belongs to the Special Issue Centrifugal (Compact-Disc) Microfluidics for Extreme POC)
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This paper presents an innovative mixing technology for centrifugal microfluidic platforms actuated using a specially designed flyball governor. The multilayer microfluidic disc was fabricated using a polydimethylsiloxane (PDMS) replica molding process with a soft lithography technique. The operational principle is based on the interaction between the elastic covering membrane and an actuator pin installed on the flyball governor system. The flyball governor was used as the transducer to convert the rotary motion into a reciprocating linear motion of the pin pressing against the covering membrane of the mixer chamber. When the rotation speed of the microfluidic disc was periodically altered, the mixing chamber was compressed and released accordingly. In this way, enhanced active mixing can be achieved with much better efficiency in comparison with diffusive mixing. View Full-Text
Keywords: micromixer; centrifugal microfluidics; PDMS; active micro-mixing; lab-on-CD; flyball governor actuated; chaotic mixing micromixer; centrifugal microfluidics; PDMS; active micro-mixing; lab-on-CD; flyball governor actuated; chaotic mixing

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Cai, Z.; Xiang, J.; Chen, H.; Wang, W. A Rapid Micromixer for Centrifugal Microfluidic Platforms. Micromachines 2016, 7, 89.

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