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Micromachines, Volume 12, Issue 8

August 2021 - 153 articles

Cover Story: The upregulated expression of tyrosine kinase AXL has been reported in several hematologic and solid human tumors, including gastric, breast, colorectal, prostate and ovarian cancers. Thus, AXL can potentially serve as a diagnostic and prognostic biomarker for various cancers. This paper reports the first ever loop-mediated isothermal amplification (LAMP) in a core-shell bead assay for the detection of AXL gene overexpression. We demonstrated simple instrumentation toward a point-of-care device to perform LAMP. This paper also reports the first ever use of core-shell beads as a microreactor to perform LAMP, as an attempt to promote environmentally friendly laboratory practices. View this paper.
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Articles (153)

  • Article
  • Open Access
9 Citations
3,594 Views
23 Pages

Dynamic Performance of Partially Orifice Porous Aerostatic Thrust Bearing

  • Muhammad Punhal Sahto,
  • Wei Wang,
  • Ali Nawaz Sanjrani,
  • Chengxu Hao and
  • Sadiq Ali Shah

20 August 2021

The aerostatic thrust bearing’s performance under vibration brings certain changes in stiffness and stability, especially in the range of 100 to 10,000 Hz, and it is accompanied by significant increase in fluctuations due to the changes in frequency,...

  • Review
  • Open Access
36 Citations
9,747 Views
21 Pages

The Development of Design and Manufacture Techniques for Bioresorbable Coronary Artery Stents

  • Liang Wang,
  • Li Jiao,
  • Shuoshuo Pang,
  • Pei Yan,
  • Xibin Wang and
  • Tianyang Qiu

20 August 2021

Coronary artery disease (CAD) is the leading killer of humans worldwide. Bioresorbable polymeric stents have attracted a great deal of interest because they can treat CAD without producing long-term complications. Bioresorbable polymeric stents (BMSs...

  • Review
  • Open Access
192 Citations
34,420 Views
25 Pages

20 August 2021

This paper reviews the recent advances in reaction-ion etching (RIE) for application in high-aspect-ratio microfabrication. High-aspect-ratio etching of materials used in micro- and nanofabrication has become a very important enabling technology part...

  • Article
  • Open Access
6 Citations
6,838 Views
16 Pages

Pump-Free Microfluidic Hemofiltration Device

  • Takahiro Ito,
  • Takashi Ota,
  • Rei Kono,
  • Yoshitaka Miyaoka,
  • Hidetoshi Ishibashi,
  • Masaki Komori,
  • Akio Yasukawa,
  • Yoshihiko Kanno and
  • Norihisa Miki

20 August 2021

Hemofiltration removes water and small molecules from the blood via nanoporous filtering membranes. This paper discusses a pump-free hemofiltration device driven by the pressure difference between the artery and the vein. In the design of the filteri...

  • Article
  • Open Access
5 Citations
3,863 Views
15 Pages

20 August 2021

SlipChips are two-part microfluidic devices that can be reconfigured to change fluidic pathways for a wide range of functions, including tissue stimulation. Currently, fabrication of these devices at the prototype stage requires a skilled microfluidi...

  • Article
  • Open Access
10 Citations
3,483 Views
17 Pages

Towards Biohybrid Lung: Induced Pluripotent Stem Cell Derived Endothelial Cells as Clinically Relevant Cell Source for Biologization

  • Michael Pflaum,
  • Julia Dahlmann,
  • Lena Engels,
  • Hossein Naghilouy-Hidaji,
  • Denise Adam,
  • Janina Zöllner,
  • Annette Otto,
  • Sabrina Schmeckebier,
  • Ulrich Martin and
  • Axel Haverich
  • + 2 authors

19 August 2021

In order to provide an alternative treatment option to lung transplantation for patients with end-stage lung disease, we aim for the development of an implantable biohybrid lung (BHL), based on hollow fiber membrane (HFM) technology used in extracorp...

  • Article
  • Open Access
16 Citations
4,359 Views
13 Pages

19 August 2021

A diamagnetically stabilized levitation structure is composed of a floating magnet, diamagnetic material, and a lifting magnet. The floating magnet is freely levitated between two diamagnetic plates without any external energy input. In this paper, t...

  • Article
  • Open Access
15 Citations
6,273 Views
16 Pages

19 August 2021

Kidney microphysiological systems (MPS) serve as potentially valuable preclinical instruments in probing mechanisms of renal clearance and osmoregulation. Current kidney MPS models target regions of the nephron, such as the glomerulus and proximal tu...

  • Article
  • Open Access
21 Citations
3,590 Views
21 Pages

Noncascading Quadratic Buck-Boost Converter for Photovoltaic Applications

  • Rodrigo Loera-Palomo,
  • Jorge A. Morales-Saldaña,
  • Michel Rivero,
  • Carlos Álvarez-Macías and
  • Cesar A. Hernández-Jacobo

19 August 2021

The development of switching converters to perform with the power processing of photovoltaic (PV) applications has been a topic receiving growing interest in recent years. This work presents a nonisolated buck-boost converter with a quadratic voltage...

  • Article
  • Open Access
13 Citations
2,780 Views
17 Pages

19 August 2021

A passive micromixer was designed by combining two mixing units: the cross-channel split and recombined (CC-SAR) and a mixing cell with baffles (MC-B). The passive micromixer was comprised of eight mixing slots that corresponded to four combination u...

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Micromachines - ISSN 2072-666X