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Toxins, Volume 8, Issue 11

November 2016 - 41 articles

Cover Story: C. perfringens type D strain CN3718 attachment to Caco-2 cells. C. perfringens CN3718 produces sialidases named NanH, NanI and NanJ. When the wild-type strain, an isogenic triple sialidase mutant, or a NanI complementing strain were incubated with human Caco-2 cells and then gently washed, the wild-type and complementing strain attached well to Caco-2 cells, as detected by immunofluorescence microscopy. However, the isogenic mutant with all three sialidase genes disrupted attached poorly to Caco-2 cells. Similar complementation of the triple sialidase mutant to express NanH or NanJ did not increase attachment. Green:C. perfringens; Red: Caco-2 cells. From: PLoS Pathogens 2011 Dec;7(12):e1002429.View this paper.
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Articles (41)

  • Review
  • Open Access
433 Citations
36,202 Views
11 Pages

Trimethylamine N-Oxide: The Good, the Bad and the Unknown

  • Manuel T. Velasquez,
  • Ali Ramezani,
  • Alotaibi Manal and
  • Dominic S. Raj

8 November 2016

Trimethylamine N-oxide (TMAO) is a small colorless amine oxide generated from choline, betaine, and carnitine by gut microbial metabolism. It accumulates in the tissue of marine animals in high concentrations and protects against the protein-destabil...

  • Article
  • Open Access
47 Citations
7,495 Views
14 Pages

Tenuifolide B from Cinnamomum tenuifolium Stem Selectively Inhibits Proliferation of Oral Cancer Cells via Apoptosis, ROS Generation, Mitochondrial Depolarization, and DNA Damage

  • Chung-Yi Chen,
  • Ching-Yu Yen,
  • Hui-Ru Wang,
  • Hui-Ping Yang,
  • Jen-Yang Tang,
  • Hurng-Wern Huang,
  • Shih-Hsien Hsu and
  • Hsueh-Wei Chang

5 November 2016

The development of drugs that selectively kill oral cancer cells but are less harmful to normal cells still provide several challenges. In this study, the antioral cancer effects of tenuifolide B (TFB), extracted from the stem of the plant Cinnamomum...

  • Article
  • Open Access
18 Citations
6,911 Views
21 Pages

5 November 2016

B. cereus is an opportunistic foodborne pathogen able to cause diarrhoea. However, the diarrhoeal potential of a B. cereus strain remains difficult to predict, because no simple correlation has yet been identified between the symptoms and a unique or...

  • Article
  • Open Access
15 Citations
13,067 Views
15 Pages

Pueraria mirifica Exerts Estrogenic Effects in the Mammary Gland and Uterus and Promotes Mammary Carcinogenesis in Donryu Rats

  • Anna Kakehashi,
  • Midori Yoshida,
  • Yoshiyuki Tago,
  • Naomi Ishii,
  • Takahiro Okuno,
  • Min Gi and
  • Hideki Wanibuchi

4 November 2016

Pueraria mirifica (PM), a plant whose dried and powdered tuberous roots are now widely used in rejuvenating preparations to promote youthfulness in both men and women, may have major estrogenic influence. In this study, we investigated modifying effe...

  • Article
  • Open Access
62 Citations
8,229 Views
17 Pages

Presence or Absence of mlr Genes and Nutrient Concentrations Co-Determine the Microcystin Biodegradation Efficiency of a Natural Bacterial Community

  • María Ángeles Lezcano,
  • Jesús Morón-López,
  • Ramsy Agha,
  • Isabel López-Heras,
  • Leonor Nozal,
  • Antonio Quesada and
  • Rehab El-Shehawy

3 November 2016

The microcystin biodegradation potential of a natural bacterial community coexisting with a toxic cyanobacterial bloom was investigated in a water reservoir from central Spain. The biodegradation capacity was confirmed in all samples during the bloom...

  • Article
  • Open Access
16 Citations
6,515 Views
18 Pages

RNA Sequencing of Contaminated Seeds Reveals the State of the Seed Permissive for Pre-Harvest Aflatoxin Contamination and Points to a Potential Susceptibility Factor

  • Josh Clevenger,
  • Kathleen Marasigan,
  • Vasileios Liakos,
  • Victor Sobolev,
  • George Vellidis,
  • Corley Holbrook and
  • Peggy Ozias-Akins

3 November 2016

Pre-harvest aflatoxin contamination (PAC) is a major problem facing peanut production worldwide. Produced by the ubiquitous soil fungus, Aspergillus flavus, aflatoxin is the most naturally occurring known carcinogen. The interaction between fungus an...

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Toxins - ISSN 2072-6651