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Toxins, Volume 17, Issue 1

January 2025 - 45 articles

Cover Story: Aflatoxin B1 (AFB1) contamination in food crops poses significant public health risks, especially in decentralized, low-resource agricultural systems. This study evaluated AFB1 detection methods, including ELISA and lateral-flow assays (LFAs), validated via HPLC, and assessed barriers to their use. Among ELISA kits, the AgraQuant Aflatoxin B1 2/50 Kit showed the highest accuracy, reliably quantifying AFB1 in maize and tortillas. LFA paired with a smartphone algorithm achieved 84% presence/absence accuracy but struggled with concentration predictions. Low-cost tools like moisture readers aid screening, but advanced methods remain essential. A tiered framework combining tools and confirmatory testing can enhance monitoring systems in decentralized agricultural supply chains. View this paper
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Articles (45)

  • Article
  • Open Access
2,656 Views
16 Pages

13 January 2025

This study explored harmful algal bloom (HAB) risk as a function of exposure, hazard and vulnerability, using Scotland as a case study. Exposure was defined as the fish biomass estimated to be lost from a bloom event, based on the total recorded annu...

  • Article
  • Open Access
3 Citations
2,024 Views
20 Pages

Mapping Variability of Mycotoxins in Individual Oat Kernels from Batch Samples: Implications for Sampling and Food Safety

  • Irene Teixido-Orries,
  • Francisco Molino,
  • Bianca Castro-Criado,
  • Monika Jodkowska,
  • Angel Medina,
  • Sonia Marín and
  • Carol Verheecke-Vaessen

11 January 2025

Oats are susceptible to contamination by Fusarium mycotoxins, including deoxynivalenol (DON), zearalenone (ZEN), and T-2/HT-2 toxins, posing food safety risks. This study analyses the variation in levels of 14 mycotoxins in 200 individual oat kernels...

  • Article
  • Open Access
3 Citations
2,141 Views
17 Pages

11 January 2025

Fusarium fungi are widespread pathogens of food crops, primarily associated with the formation of mycotoxins. Therefore, effective mitigation strategies for these toxicogenic microorganisms are required. In this study, the potential of pulsed electri...

  • Article
  • Open Access
2,121 Views
13 Pages

Encapsulated LyeTx III Peptide: Cytotoxic Agent Isolated from Lycosa erythrognatha Spider Venom

  • Daniel Moreira dos Santos,
  • Livia Ramos Santiago,
  • Nayara Araújo dos Santos,
  • Wanderson Romão,
  • Jarbas Magalhães Resende,
  • Maria Elena de Lima,
  • Márcia Helena Borges and
  • Rosy Iara Maciel de Azambuja Ribeiro

10 January 2025

The discovery of novel cytotoxic drugs is of paramount importance in contemporary medical research, particularly in the search for treatments with fewer side effects and higher specificity. Antimicrobial peptides are an interesting class of molecules...

  • Review
  • Open Access
2 Citations
5,676 Views
12 Pages

The Esthetic Use of Botulinum Toxins in Cancer Patients: Providing a Foundation for Future Indications

  • Marco Papagni,
  • Monica Renga,
  • Selene Mogavero,
  • Paolo Veronesi and
  • Maurizio Cavallini

10 January 2025

Advances in oncological treatments have improved the survival rates of cancer patients but have often resulted in significant physical changes that negatively impact their self-esteem and psychological well-being. Cancer patients frequently ask esthe...

  • Review
  • Open Access
17 Citations
7,832 Views
44 Pages

9 January 2025

It has been known since the early days of the discovery of aflatoxin B1 (AFB1) that there were large species differences in susceptibility to AFB1. It was also evident early on that AFB1 itself was not toxic but required bioactivation to a reactive f...

  • Article
  • Open Access
4 Citations
1,758 Views
18 Pages

Proteomic Analysis of the Murine Liver Response to Oral Exposure to Aflatoxin B1 and Ochratoxin A: The Protective Role to Bioactive Compounds

  • Silvia Trombetti,
  • Alessandra Cimbalo,
  • Michela Grosso,
  • Pilar Vila-Donat,
  • Jordi Mañes and
  • Lara Manyes

9 January 2025

Aflatoxin B1 (AFB1) and Ochratoxin A (OTA) are considered the most important mycotoxins in terms of food safety. The aim of this study was to evaluate the hepatotoxicity of AFB1 and OTA exposure in Wistar rats and to assess the beneficial effect of f...

  • Article
  • Open Access
2 Citations
1,465 Views
10 Pages

7 January 2025

Prorocentrum, a dinoflagellate responsible for producing diarrhetic shellfish poisoning (DSP) toxins, poses significant threats to marine ecosystems, aquaculture industries, and human health. DSP toxins, including okadaic acid (OA), dinophysis toxin...

  • Article
  • Open Access
2 Citations
2,454 Views
16 Pages

Does Clostridium Perfringens Epsilon Toxin Mimic an Auto-Antigen Involved in Multiple Sclerosis?

  • Marie-Lise Gougeon,
  • Valérie Seffer,
  • Cezarela Hoxha,
  • Elisabeth Maillart and
  • Michel R. Popoff

7 January 2025

Multiple sclerosis (MS) is a chronic immune-mediated neurological disorder, characterized by progressive demyelination and neuronal cell loss in the central nervous system. Many possible causes of MS have been proposed, including genetic factors, env...

  • Article
  • Open Access
1 Citations
1,420 Views
19 Pages

6 January 2025

Significant agro-industrial waste is produced during the winemaking process, including grape stalks, which are a rich source of the valuable biopolymer holocellulose that can be utilized for biotechnological processes. The purpose of this study was t...

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Toxins - ISSN 2072-6651