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Toxins, Volume 16, Issue 8

August 2024 - 47 articles

Cover Story: Conotoxins are powerful neuroactive components discovered in the venom of the marine gastropods of the genus Conus and present in many other conoidean taxa. From the transcriptome of the salivary glands and venom duct of Raphitoma purpurea, >100 putative venom components and 20 novel toxin families were retrieved. Among them, some salivary peptides showed high resemblance to cone snail toxins and toxin chaperones. Conversely, the peptides expressed in the venom duct had little similarity with known toxins and may represent bioactive substances new to science. These findings suggest that some of the earliest adaptations for venom production in conoideans may actually concern their salivary secretions. View this paper
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Articles (47)

  • Systematic Review
  • Open Access
3 Citations
3,029 Views
17 Pages

Resistance of Transgenic Maize Cultivars to Mycotoxin Production—Systematic Review and Meta-Analysis

  • Ana Silvia de Lara Pires Batista Gomes,
  • Saulo Henrique Weber and
  • Fernando Bittencourt Luciano

22 August 2024

Approximately 25% of cereal grains present with contamination caused by fungi and the presence of mycotoxins that may cause severe adverse effects when consumed. Maize has been genetically engineered to present different traits, such as fungal or ins...

  • Article
  • Open Access
3 Citations
2,403 Views
14 Pages

A Multi-Year Study of Mycotoxin Co-Occurrence in Wheat and Corn Grown in Ontario, Canada

  • Megan J. Kelman,
  • J. David Miller,
  • Justin B. Renaud,
  • Daria Baskova and
  • Mark W. Sumarah

22 August 2024

Mycotoxin emergence and co-occurrence trends in Canadian grains are dynamic and evolving in response to changing weather patterns within each growing season. The mycotoxins deoxynivalenol and zearalenone are the dominant mycotoxins detected in grains...

  • Article
  • Open Access
2 Citations
2,757 Views
12 Pages

Delphi Analysis: Optimizing Anatomy Teaching and Ultrasound Training for Botulinum Neurotoxin Type A Injection in Spasticity and Dystonia

  • Kimberly Heckert,
  • Bo Biering-Sørensen,
  • Tobias Bäumer,
  • Omar Khan,
  • Fernando Pagan,
  • Mitchell Paulin,
  • Todd Stitik,
  • Monica Verduzco-Gutierrez and
  • Rajiv Reebye

21 August 2024

Our objective was to provide expert consensus on best practices for anatomy teaching and training on ultrasound-guided botulinum neurotoxin type A (BoNT-A) injection for specialists involved in treating spasticity and dystonia. Nine experts (three ne...

  • Article
  • Open Access
2 Citations
2,253 Views
19 Pages

Nanofractionation Analytics for Comparing MALDI-MS and ESI-MS Data of Viperidae Snake Venom Toxins

  • Haifeng Xu,
  • Jesse Mastenbroek,
  • Natascha T. B. Krikke,
  • Susan El-Asal,
  • Rama Mutlaq,
  • Nicholas R. Casewell,
  • Julien Slagboom and
  • Jeroen Kool

21 August 2024

Worldwide, it is estimated that there are 1.8 to 2.7 million cases of envenoming caused by snakebites. Snake venom is a complex mixture of protein toxins, lipids, small molecules, and salts, with the proteins typically responsible for causing patholo...

  • Article
  • Open Access
1 Citations
1,768 Views
12 Pages

21 August 2024

Lysinibacillus sphaericus harboring Binary (BinA and BinB) toxins is highly toxic against Anopheles and Culex mosquito larvae. The Anopheles Ag55 cell line is a suitable model for investigating the mode of Bin toxin action. Based on the low-levels of...

  • Review
  • Open Access
2 Citations
1,594 Views
8 Pages

Bacterial Porins and Their Procoagulant Role: Implication in the Pathophysiology of Several Thrombotic Complications during Sepsis

  • Carmine Siniscalchi,
  • Alessandro Perrella,
  • Ugo Trama,
  • Francesca Futura Bernardi,
  • Egidio Imbalzano,
  • Giuseppe Camporese,
  • Vincenzo Russo,
  • Olga Scudiero,
  • Tiziana Meschi and
  • Pierpaolo Di Micco

20 August 2024

The association between sepsis and thrombotic complications is still not well known. Different mechanisms have been shown to be involved in the sepsis-induced prothrombotic state, but clinical scenarios may differ. In this review, we have summarized...

  • Article
  • Open Access
4 Citations
2,348 Views
14 Pages

Aflatoxin B1 Control by Various Pseudomonas Isolates

  • Dóra Anna Papp,
  • Sándor Kocsubé,
  • Zoltán Farkas,
  • András Szekeres,
  • Csaba Vágvölgyi,
  • Zsuzsanna Hamari and
  • Mónika Varga

20 August 2024

The climate-change-coupled fungal burden in crop management and the need to reduce chemical pesticide usage highlight the importance of finding sustainable ways to control Aspergillus flavus. This study examines the effectiveness of 50 Pseudomonas is...

  • Article
  • Open Access
3 Citations
2,575 Views
15 Pages

Real-World Observational Analysis of Clinical Characteristics and Treatment Patterns of Patients with Chronic Sialorrhea

  • Michael A. Hast,
  • Amanda M. Kong,
  • Jenna Abdelhadi,
  • Rohan Shah,
  • Andrew Szendrey and
  • Jordan Holmes

17 August 2024

Chronic sialorrhea is a condition characterized by excessive drooling, often associated with neurological and neuromuscular disorders such as Parkinson’s disease, cerebral palsy, and stroke. Despite its prevalence, it remains underdiagnosed and...

  • Article
  • Open Access
2,672 Views
13 Pages

Treatment of Acquired Deforming Hypertonia with Botulinum Toxin in Older Population: A Retrospective Study

  • Pablo Maldonado,
  • Hugo Bessaguet,
  • Cédric Chol,
  • Pascal Giraux,
  • Ludovic Lafaie,
  • Ahmed Adham,
  • Romain David,
  • Thomas Celarier and
  • Etienne Ojardias

16 August 2024

Acquired deforming hypertonia (ADH) affects the daily care of numerous nursing home residents. The aim of this study was to analyze the practice, aims, and effectiveness of botulinum toxin injections (BTxis) in the treatment of older patients with co...

  • Article
  • Open Access
4 Citations
2,549 Views
13 Pages

16 August 2024

Background: The reduction in joint load is a potential beneficial factor in managing osteoarthritis of the temporomandibular joint (TMJ). This paper aims to compare the effectiveness of the intramuscular injection of botulinum toxin (BTX-A) as an adj...

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Toxins - ISSN 2072-6651