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Toxins, Volume 16, Issue 7

July 2024 - 43 articles

Cover Story: Molecular imaging enables non-invasive visualisation of biochemical processes in living organisms. Optical fluorescent imaging, in particular, offers real-time insights into the dynamic behaviour of targets of interest. Ion channels are important in cellular signalling and are involved in various pathological conditions, rendering them key targets for molecular imaging. Venom peptides, known for their selectivity and potency towards ion channels, offer a unique approach to molecular imaging. This review highlights the use of fluorescently labelled venom peptides for disease diagnostics and intraoperative imaging of brain tumours and peripheral nerves, addressing challenges for the development and clinical translation of venom peptides as nerve-targeted imaging agents. View this paper
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Articles (43)

  • Article
  • Open Access
6 Citations
3,128 Views
14 Pages

Urea Level and Depression in Patients with Chronic Kidney Disease

  • Hélène Levassort,
  • Julie Boucquemont,
  • Oriane Lambert,
  • Sophie Liabeuf,
  • Solene M. Laville,
  • Laurent Teillet,
  • Abdel-Hay Tabcheh,
  • Luc Frimat,
  • Christian Combe and
  • Denis Fouque
  • + 7 authors

22 July 2024

Depression is common in patients with chronic kidney disease (CKD). Experimental studies suggest the role of urea toxicity in depression. We assessed both the incidence of antidepressant prescriptions and depressive symptoms (measured by CESD (Center...

  • Article
  • Open Access
1,904 Views
14 Pages

22 July 2024

Shiga toxin-producing Escherichia coli (STEC) causes a wide spectrum of diseases including hemorrhagic colitis and hemolytic uremic syndrome (HUS). Previously, we developed a rapid, sensitive, and potentially portable assay that identified STEC by de...

  • Article
  • Open Access
1,481 Views
13 Pages

Effects of Different Shelling Methods on Data Variability during Field Screening for Reduced Aflatoxin Contamination in Maize

  • Alison Adams,
  • Daniel Jeffers,
  • Shien Lu,
  • Baozhu Guo,
  • W. Paul Williams and
  • Jake C. Fountain

19 July 2024

Non-genetic variation limits the identification of novel maize germplasm with genetic markers for reduced Aspergillus flavus infection and aflatoxin contamination. Aflatoxin measurements can vary substantially within fields containing the same germpl...

  • Review
  • Open Access
1 Citations
2,676 Views
18 Pages

19 July 2024

Numerous studies have established a robust body of evidence for botulinum toxin A (BoNT-A) therapy as a treatment for upper motor neuron syndrome. These studies demonstrated improvements in spasticity, range of joint motion, and pain reduction. Howev...

  • Article
  • Open Access
1 Citations
2,229 Views
16 Pages

18 July 2024

The toxic nature of bacterial endotoxins is affected by the structural details of lipid A, including the variety and position of acyl chains and phosphate group(s) on its diglucosamine backbone. Negative-ion mode tandem mass spectrometry is a primary...

  • Article
  • Open Access
3 Citations
2,030 Views
13 Pages

Citrinin Provoke DNA Damage and Cell-Cycle Arrest Related to Chk2 and FANCD2 Checkpoint Proteins in Hepatocellular and Adenocarcinoma Cell Lines

  • Darija Stupin Polančec,
  • Sonja Homar,
  • Daniela Jakšić,
  • Nevenka Kopjar,
  • Maja Šegvić Klarić and
  • Sanja Dabelić

17 July 2024

Citrinin (CIT), a polyketide mycotoxin produced by Penicillium, Aspergillus, and Monascus species, is a contaminant that has been found in various food commodities and was also detected in house dust. Several studies showed that CIT can impair the ki...

  • Article
  • Open Access
3 Citations
4,149 Views
11 Pages

Treatment of Primary Axillary Hyperhidrosis with Two Doses of Botulinum Toxin A—Observational Study

  • María Jesús Antón Andrés,
  • Ernesto Domingo Candau Pérez and
  • María Pilar Bermejo de la Fuente

16 July 2024

Hyperhidrosis (HH) is defined as the production of more sweat than is necessary for its thermoregulatory function, negatively affecting patients’ quality of life and interfering with their social, work and family life. In this context, the aim of thi...

  • Article
  • Open Access
2 Citations
1,947 Views
21 Pages

15 July 2024

Tenuazonic acid (TeA), usually found in cereals, fruits, vegetables, oil crops, and their products, was classified as one of the highest public health problems by EFSA as early as 2011, but it has still not been regulated by legislation due to the li...

  • Article
  • Open Access
2 Citations
1,931 Views
14 Pages

13 July 2024

Maize plays a significant global role as a food source, feed, and as a raw material in industry. However, it is affected by toxin-producing fungi, mainly Fusarium graminearum, Fusarium verticillioides, and Aspergillus flavus, which compromise its qua...

  • Article
  • Open Access
2,467 Views
12 Pages

12 July 2024

Botulinum neurotoxin (BNT) injection into the cricopharyngeus muscle (CPM) under ultrasound (US) guidance is a minimally invasive technique performed to relieve cricopharyngeal dysphagia by reducing CPM spasticity. This technique is basically accessi...

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Toxins - ISSN 2072-6651Creative Common CC BY license