Neurology International, Volume 15, Issue 3
September 2023 - 27 articles
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Cover Story: Long-COVID has been a major consequence of the COVID-19 pandemic and continues to be a worldwide health concern. In particular, neurologic symptoms that linger beyond the acute phase of the disease can cause drastic negative effects on a patient’s ability to function and quality of life. Among the major central nervous system clinical manifestations of long-COVID are brain fog, headache, sleep disturbances, fatigue and depression. Sensorimotor symptoms experienced beyond 12 weeks after initial COVID-19 infection include neuropathic pain, myalgias and muscle weakness. Proposed pathological mechanisms underlying these symptoms generally focus on neuroinflammatory and systemic inflammatory processes, immune dysregulation and cerebral metabolic dysfunction. Treatment options are limited and a focus of intensive research. View this paper