Cerebellar Progressive Multifocal Leukoencephalopathy Mimicking Anti-Yo-Antibody-Associated Rapidly Progressive Cerebellar Syndrome
Abstract
1. Introduction
2. Case Presentation
3. Discussion
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Age/Sex | Past History Other than SLE | Steroid (mg/day) | Immunosuppressant | Specimen/JCV Copy Number (Copies/mL) | Treatment | JCV-DNA Copy Number Trends | Follow-up Period/Prognosis | References | ||
---|---|---|---|---|---|---|---|---|---|---|
Meflo- quine | Mirtaz- apine | Other | ||||||||
50/F | Lymphoma | PSL/5 | MMF, RIT, Bendamustine | CSF, brain biopsy | + | + | None | N.A. | 5 m/dead | Sakuraba [19] |
68/M | None | N.A. | TAC, MTX | CSF | + | + | None | Neg/6 m | 9 m/alive | Hamaguchi [16] |
60/F | None | PSL/12 | MTX | CSF/67,000 | − | − | N.A. | N.A. | 3 m/dead | Zhong [38] |
27/F | RA | PSL/10–20 | ETN, TOC, RIT, MTX | CSF | + | − | DFPP, Paroxetine | Neg/4 m | 12 m/alive | Cheng [14] |
34/F | None | Deflazacort/6 | AZA | CSF/700 | + | + | CDV, Ara-C | Increased/6 m | 12 m /dead | Berntsson [12] |
32/F | HPS | N.A. | CPA, AZA, MTX, RIT, Thalidomide | CSF | − | − | CDV | N.A. | N.A. | Brandão [13] |
23/F | RA | PSL/10–20 | Hydroxychloroquine, ETN | CSF/28,600 | − | − | Ara-C, PE | N.A. | N.A./dead | Graff-Radford [15] |
51/M | N.A. | N.A. | N.A. | Biopsy | N.A. | N.A. | N.A. | N.A. | 36 m/alive | Svensson [37] |
36/F | None | PSL N.A. | CYA | CSF | − | − | CDV | Neg/74 days | 7 m/dead | Salmaggi [20] |
21/F | None | PSL/30 | None | Autopsy | − | − | Interferon | N.A. | 23 m/dead | Kinoshita [18] |
55/F | None | PSL/15 | None | Biopsy | − | − | None | N.A. | 3 m/dead | Jones [17] |
57/F | None | PSL/5 | MMF | CSF/15,8700 | + | + | None | Neg/26 m | 27 m/alive | Our case |
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Akimoto, T.; Hara, M.; Hirose, S.; Nakamichi, K.; Nakajima, H. Cerebellar Progressive Multifocal Leukoencephalopathy Mimicking Anti-Yo-Antibody-Associated Rapidly Progressive Cerebellar Syndrome. Neurol. Int. 2023, 15, 917-925. https://doi.org/10.3390/neurolint15030059
Akimoto T, Hara M, Hirose S, Nakamichi K, Nakajima H. Cerebellar Progressive Multifocal Leukoencephalopathy Mimicking Anti-Yo-Antibody-Associated Rapidly Progressive Cerebellar Syndrome. Neurology International. 2023; 15(3):917-925. https://doi.org/10.3390/neurolint15030059
Chicago/Turabian StyleAkimoto, Takayoshi, Makoto Hara, Satoshi Hirose, Kazuo Nakamichi, and Hideto Nakajima. 2023. "Cerebellar Progressive Multifocal Leukoencephalopathy Mimicking Anti-Yo-Antibody-Associated Rapidly Progressive Cerebellar Syndrome" Neurology International 15, no. 3: 917-925. https://doi.org/10.3390/neurolint15030059
APA StyleAkimoto, T., Hara, M., Hirose, S., Nakamichi, K., & Nakajima, H. (2023). Cerebellar Progressive Multifocal Leukoencephalopathy Mimicking Anti-Yo-Antibody-Associated Rapidly Progressive Cerebellar Syndrome. Neurology International, 15(3), 917-925. https://doi.org/10.3390/neurolint15030059