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Pharmaceutics, Volume 2, Issue 3

September 2010 - 4 articles

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Articles (4)

  • Article
  • Open Access
6 Citations
7,701 Views
8 Pages

Impact of Oral Fast Release Amantadine on Movement Performance in Patients with Parkinson’s Disease

  • Siegfried Muhlack,
  • Patricia Müsch,
  • Sandra Konietzka,
  • Dirk Woitalla,
  • Horst Przuntek and
  • Thomas Müller

20 September 2010

Application of oral fast release amantadine and levodopa may induce an improvement of motor symptoms in patients with Parkinson’s disease (PD). The objective of this trial was to investigate the clinical efficacy of a fast release amantadine sulfate...

  • Review
  • Open Access
37 Citations
10,112 Views
9 Pages

9 September 2010

Tacrolimus is a calcineurin inhibitor immunosuppressant that has seen considerable use in both adult and pediatric solid organ transplant recipients. Though there is much pharmacokinetic data available for tacrolimus in the adult population, the lite...

  • Article
  • Open Access
3 Citations
7,428 Views
13 Pages

Expression of Drug-Resistant Factor Genes in Hepatocellular Carcinoma Patients Undergoing Chemotherapy with Platinum Complex by Arterial Infusion

  • Tomoya Sakurada,
  • Masaharu Yoshikawa,
  • Masahiko Sunaga,
  • Eriko Kobayashi,
  • Nobunori Satoh,
  • Osamu Yokosuka and
  • Shiro Ueda

9 September 2010

This study investigated gene expression of drug resistance factors in biopsy tissue samples from hepatocellular carcinoma (HCC) patients undergoing chemotherapy by platinum complex. Liver biopsy was performed to collect tissue from the tumor site (T)...

  • Article
  • Open Access
63 Citations
14,695 Views
16 Pages

Effect of Moisture on Powder Flow Properties of Theophylline

  • Niklas Sandler,
  • Katharina Reiche,
  • Jyrki Heinämäki and
  • Jouko Yliruusi

Powder flow is influenced by environmental factors, such as moisture and static electricity, as well as powder related factors, such as morphology, size, size distribution, density, and surface area. Pharmaceutical solids may be exposed to water duri...

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Pharmaceutics - ISSN 1999-4923