Pharmaceutics, Volume 11, Issue 6 (June 2019) – 48 articles
Cover Story (view full-size image): Poly(lactic-co-glycolic acid) (PLGA) has been widely used for biomedical applications due to its biocompatibility and biodegradability. Nanoparticles (NPs) based on PLGA and PLGA derivatives have been developed for cancer imaging and therapy after intravenous injection. Imaging modalities and therapeutic cargos can be encapsulated in PLGA-based NPs or attached onto the outer surface of NPs. In addition, tumor targeting moieties can be installed in the exterior part of PLGA-based NPs to accomplish active tumor targeting capability along with passive tumor targeting effect. Safety and versatility of PLGA-based NPs can elevate their feasibility for clinical application in cancer therapy. View this paper.
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