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Viruses, Volume 8, Issue 12

December 2016 - 19 articles

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Articles (19)

  • Review
  • Open Access
43 Citations
10,716 Views
22 Pages

RNA Interference in Insect Vectors for Plant Viruses

  • Surapathrudu Kanakala and
  • Murad Ghanim

12 December 2016

Insects and other arthropods are the most important vectors of plant pathogens. The majority of plant pathogens are disseminated by arthropod vectors such as aphids, beetles, leafhoppers, planthoppers, thrips and whiteflies. Transmission of plant pat...

  • Article
  • Open Access
17 Citations
6,897 Views
21 Pages

Serro 2 Virus Highlights the Fundamental Genomic and Biological Features of a Natural Vaccinia Virus Infecting Humans

  • Giliane De Souza Trindade,
  • Ginny L. Emerson,
  • Scott Sammons,
  • Michael Frace,
  • Dhwani Govil,
  • Bruno Eduardo Fernandes Mota,
  • Jônatas Santos Abrahão,
  • Felipe Lopes De Assis,
  • Melissa Olsen-Rasmussen and
  • Cynthia S. Goldsmith
  • + 5 authors

10 December 2016

Vaccinia virus (VACV) has been implicated in infections of dairy cattle and humans, and outbreaks have substantially impacted local economies and public health in Brazil. During a 2005 outbreak, a VACV strain designated Serro 2 virus (S2V) was collec...

  • Article
  • Open Access
7 Citations
6,201 Views
16 Pages

Characterization of an Immunodominant Epitope in the Endodomain of the Coronavirus Membrane Protein

  • Hui Dong,
  • Xin Zhang,
  • Hongyan Shi,
  • Jianfei Chen,
  • Da Shi,
  • Yunnuan Zhu and
  • Li Feng

10 December 2016

The coronavirus membrane (M) protein acts as a dominant immunogen and is a major player in virus assembly. In this study, we prepared two monoclonal antibodies (mAbs; 1C3 and 4C7) directed against the transmissible gastroenteritis virus (TGEV) M prot...

  • Article
  • Open Access
14 Citations
5,468 Views
11 Pages

Evaluation of microRNA Expression in Patients with Herpes Zoster

  • Xihan Li,
  • Ying Huang,
  • Yucheng Zhang and
  • Na He

2 December 2016

Reactivated varicella-zoster virus (VZV), which lies latent in the dorsal root ganglions and cranial nerves before its reactivation, is capable of causing herpes zoster (HZ), but the specific mechanism of virus reactivation and latency remains unknow...

  • Article
  • Open Access
116 Citations
10,840 Views
17 Pages

Capsule-Targeting Depolymerase, Derived from Klebsiella KP36 Phage, as a Tool for the Development of Anti-Virulent Strategy

  • Grażyna Majkowska-Skrobek,
  • Agnieszka Łątka,
  • Rita Berisio,
  • Barbara Maciejewska,
  • Flavia Squeglia,
  • Maria Romano,
  • Rob Lavigne,
  • Carsten Struve and
  • Zuzanna Drulis-Kawa

1 December 2016

The rise of antibiotic-resistant Klebsiella pneumoniae, a leading nosocomial pathogen, prompts the need for alternative therapies. We have identified and characterized a novel depolymerase enzyme encoded by Klebsiella phage KP36 (depoKP36), from the...

  • Article
  • Open Access
9 Citations
6,749 Views
11 Pages

Ion Channel Activity of Vpu Proteins Is Conserved throughout Evolution of HIV-1 and SIV

  • Timo Greiner,
  • Sebastian Bolduan,
  • Brigitte Hertel,
  • Christine Groß,
  • Kay Hamacher,
  • Ulrich Schubert,
  • Anna Moroni and
  • Gerhard Thiel

1 December 2016

The human immunodeficiency virus type 1 (HIV-1) protein Vpu is encoded exclusively by HIV-1 and related simian immunodeficiency viruses (SIVs). The transmembrane domain of the protein has dual functions: it counteracts the human restriction factor te...

  • Article
  • Open Access
237 Citations
20,710 Views
15 Pages

Chloroquine, an Endocytosis Blocking Agent, Inhibits Zika Virus Infection in Different Cell Models

  • Rodrigo Delvecchio,
  • Luiza M. Higa,
  • Paula Pezzuto,
  • Ana Luiza Valadão,
  • Patrícia P. Garcez,
  • Fábio L. Monteiro,
  • Erick C. Loiola,
  • André A. Dias,
  • Fábio J. M. Silva and
  • Matthew T. Aliota
  • + 9 authors

29 November 2016

Zika virus (ZIKV) infection in utero might lead to microcephaly and other congenital defects. Since no specific therapy is available thus far, there is an urgent need for the discovery of agents capable of inhibiting its viral replication and deleter...

  • Article
  • Open Access
38 Citations
6,739 Views
15 Pages

29 November 2016

Porcine epidemic diarrhea virus (PEDV), a predominant cause of acute enteric infection, leads to severe dehydrating diarrhea and mortality in piglets all over the world. A virulent PEDV YN13 strain, isolated in our laboratory, was attenuated to yield...

  • Article
  • Open Access
17 Citations
6,845 Views
14 Pages

26 November 2016

Infections with the influenza C virus causing respiratory symptoms are common, particularly among children. Since isolation and detection of the virus are rarely performed, compared with influenza A and B viruses, the small number of available sequen...

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Viruses - ISSN 1999-4915