Current Oncology, Volume 23, Issue 5

After controlling for ds, rd, an interaction term for ds/cs, [...]

Introduction: BRCA mutation testing allows index patients and their families to be provided with appropriate cancer risk-reduction strategies. Because of the low prevalence of BRCA mutations in unselected breast cancer patients and the high cost of g...

Background: Genomic technologies are increasingly used to guide clinical decision-making in cancer control. Economic evidence about the cost-effectiveness of genomic technologies is limited, in part because of a lack of published comprehensive cost e...

Background: Breast-conserving surgery (BCS) is the preferred surgical approach for most patients with early-stage breast cancer. Frequently, concerns arise about the pathologic margin status, resulting in an average reoperation rate of 23% in Canada....

The pan-Canadian Oncology Drug Review (PCODR) is responsible for making coverage recommendations to provincial and territorial drug plans about cancer drugs. Within the pcodr process, small groups of experts (including public representatives) conside...

Background: Therapy with anti-epidermal growth factor receptor (EGFR) monoclonal antibody improves outcomes for patients with metastatic colorectal cancer (MCRC) in the first-, second-, and third-line trial settings. In British Columbia, the use of E...

Background: In the present study, we aimed to describe, at the population level, patterns of adjuvant treatment use after curative-intent resection for pancreatic adenocarcinoma (PCC) and to identify independent predictors of adjuvant treatment use....

Background: A need for follow-up recommendations for survivors of fallopian tube, primary peritoneal, or epithelial ovarian cancer after completion of primary treatment was identified by Cancer Care Ontario’s Program in Evidence-Based Care. Methods:...

Background: As part of Choosing Wisely Canada (a national campaign to encourage patient–provider conversations about unnecessary medical tests, treatments, and procedures), a list of ten oncology practices that could be low-value in some instances wa...

Introduction: After stereotactic radiosurgery (SRS) for brain metastases, patients are routinely monitored with magnetic resonance imaging (MRI). The high rate of new brain metastases after SRS treatment alone might not be as concerning with modern M...

There can be few paradoxes quite like the life and death of the former mayor of Toronto, Rob Ford[...]

Background: No potential tumour markers have been validated for prognosis in endometrial cancer. However, carcinoembryonic antigen (CEA) is one of the most widely used tumour markers in various types of cancer. Although CEA expression in endometrial...

Background: Comparing relative costs for androgen deprivation therapy (ADT) protocols in prostate cancer (PCa) requires an examination of all health care resources, not only those specific to PCa. The objective of the present study was to use adminis...

Background: The primary objective of the present study was to examine the drug approval process and the time to approval (TTA) for cancer drugs by 3 major international regulatory bodies—Health Canada, the U.S. Food and Drug Administration (FDA), and...

Background: The overall survival (OS) analysis of the icon7 trial demonstrated that frontline ovarian cancer patients with a high risk of progression (stage III suboptimally debulked, and stage III or IV with unresectable disease) benefited from the...

Background: The use of bevacizumab in the management of glioblastoma multiforme (gbm) remains controversial. In Canada, bevacizumab is approved for the treatment of recurrent gbm. We describe a pattern of progression across treatment lines in gbm. Me...

Background and Aims: In this pilot study, we assessed the safety and tolerability of combining sorafenib with ⁹⁰Y radioembolization for the treatment of unresectable hepatocellular carcinoma (HCC). Methods: The study, conducted prospectively during 2...

Background: Phase angle could be an alternative to subjective global assessment for the assessment of nutrition status in patients with head-and-neck cancer. Methods: We prospectively evaluated a cohort of 75 stage IIIB and IV head-and-neck patients...

Aim: In the present study, we synthesized the published literature about the psychosocial aspects of colorectal cancer (crc) survivorship to support an update of the evidentiary base of the survivorship care plans (scps) created in our jurisdiction....

Objective: This evidence summary set out to assess the available evidence about the follow-up of asymptomatic survivors of lymphoma who have received curative-intent treatment. Methods: The MEDLINE and EMBASE databases and the Cochrane Database of Sy...

Case Description: A 60-year-old man developed painless neutropenic enterocolitis after induction chemotherapy for newly diagnosed acute myelogenous leukemia. The patient had recurrent fever while neutropenic, without experiencing abdominal pain or te...

We present here a very rare clinical case of a 38-year-old man with Kaposiform hemangioendothelioma (KHE) of the tongue who presented to our institution with a growth under the left side of the tongue with no pain or discomfort. There were no enlarge...

Balanced Ethics Review is intended to be a guide for members of Institutional Review Boards[...]

Sunrise in Gagliato, [...]

The ledfs was 37.8% before 2000 (all patients treated with rt).[...]