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Article

A New Standard of Care for the Management of Peritoneal Surface Malignancy

by
F. Mohamed
1,
T. Cecil
1,
B. Moran
1 and
Paul Hendrick Sugarbaker
2,*
1
Basingstoke and North Hampshire Hospital, Basingstoke, Hampshire, UK
2
Washington Cancer Institute, 106 Irving Street NW, Suite 3900, Washington, DC 20010, USA
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2011, 18(2), 84-96; https://doi.org/10.3747/co.v18i2.663
Submission received: 4 March 2011 / Revised: 8 March 2011 / Accepted: 10 March 2011 / Published: 1 April 2011

Abstract

Cancer dissemination to peritoneal surfaces was, in the past, a lethal condition with a limited survival. Clinical and pharmacologic research have shown that options for both treatment and prevention are now reality. The diseases most commonly treated include peritoneal dissemination from appendiceal malignancy, colorectal malignancy, and peritoneal mesothelioma. Selection factors are important to minimize the number of treated patients who will experience short-term benefit. Treatments involve cytoreductive surgery and perioperative chemotherapy. The intraperitoneal chemotherapy in the operating room is used with heat. Although this combined approach has been criticized, the informed oncologist will seek to identify those patients that may benefit from this more optimistic concept of peritoneal dissemination of cancer.
Keywords: Cytoreductive surgery; hyperthermic intraperitoneal chemotherapy; HIPEC; carcinomatosis; peritoneal mesothelioma; appendiceal cancer; pseudomyxoma peritonei; colorectal cancer; mitomycin C Cytoreductive surgery; hyperthermic intraperitoneal chemotherapy; HIPEC; carcinomatosis; peritoneal mesothelioma; appendiceal cancer; pseudomyxoma peritonei; colorectal cancer; mitomycin C

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MDPI and ACS Style

Mohamed, F.; Cecil, T.; Moran, B.; Sugarbaker, P.H. A New Standard of Care for the Management of Peritoneal Surface Malignancy. Curr. Oncol. 2011, 18, 84-96. https://doi.org/10.3747/co.v18i2.663

AMA Style

Mohamed F, Cecil T, Moran B, Sugarbaker PH. A New Standard of Care for the Management of Peritoneal Surface Malignancy. Current Oncology. 2011; 18(2):84-96. https://doi.org/10.3747/co.v18i2.663

Chicago/Turabian Style

Mohamed, F., T. Cecil, B. Moran, and Paul Hendrick Sugarbaker. 2011. "A New Standard of Care for the Management of Peritoneal Surface Malignancy" Current Oncology 18, no. 2: 84-96. https://doi.org/10.3747/co.v18i2.663

APA Style

Mohamed, F., Cecil, T., Moran, B., & Sugarbaker, P. H. (2011). A New Standard of Care for the Management of Peritoneal Surface Malignancy. Current Oncology, 18(2), 84-96. https://doi.org/10.3747/co.v18i2.663

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