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Case Report

Acute Aortic Thrombosis in Patients Receiving Cisplatin-Based Chemotherapy

by
D.D. Fernandes
1,
Martha L. Louzada
2,*,
C.A. Souza
1 and
F. Matzinger
1
1
University of Western Ontario, Victoria Hospital, 800 Commissioners Road East, Room E3-637, London, ON N6A 5W9, Canada
2
University of Western Ontario, Victoria Hospital, London, ON, Canada
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2011, 18(2), 97-100; https://doi.org/10.3747/co.v18i2.710
Submission received: 5 March 2011 / Revised: 9 March 2011 / Accepted: 15 March 2011 / Published: 1 April 2011

Abstract

The increased risk of thrombosis in patients with active cancer has multiple causes. Acute thrombosis of the aorta is an exceedingly rare but potentially devastating complication in patients with cancer receiving cisplatin-based chemotherapy. Prompt diagnosis and definitive treatment are imperative to decrease morbidity and mortality. Early diagnosis is difficult because initial presentation is often nonspecific, requiring a high degree of clinical suspicion. We report 4 cases of acute thrombosis of the abdominal aorta in patients with cancer receiving cisplatin-based chemotherapy. We review the clinical aspects, recommended investigation, and treatment of this potentially fatal complication.
Keywords: Acute; arterial; aortic thrombosis; aortic occlusion; cisplatin; cancer Acute; arterial; aortic thrombosis; aortic occlusion; cisplatin; cancer

Share and Cite

MDPI and ACS Style

Fernandes, D.D.; Louzada, M.L.; Souza, C.A.; Matzinger, F. Acute Aortic Thrombosis in Patients Receiving Cisplatin-Based Chemotherapy. Curr. Oncol. 2011, 18, 97-100. https://doi.org/10.3747/co.v18i2.710

AMA Style

Fernandes DD, Louzada ML, Souza CA, Matzinger F. Acute Aortic Thrombosis in Patients Receiving Cisplatin-Based Chemotherapy. Current Oncology. 2011; 18(2):97-100. https://doi.org/10.3747/co.v18i2.710

Chicago/Turabian Style

Fernandes, D.D., Martha L. Louzada, C.A. Souza, and F. Matzinger. 2011. "Acute Aortic Thrombosis in Patients Receiving Cisplatin-Based Chemotherapy" Current Oncology 18, no. 2: 97-100. https://doi.org/10.3747/co.v18i2.710

APA Style

Fernandes, D. D., Louzada, M. L., Souza, C. A., & Matzinger, F. (2011). Acute Aortic Thrombosis in Patients Receiving Cisplatin-Based Chemotherapy. Current Oncology, 18(2), 97-100. https://doi.org/10.3747/co.v18i2.710

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