Current Oncology, Volume 18, Issue 2

Monitoring Response and Resistance to Treatment in Chronic Myeloid Leukemia [...]

Euthanasia allows inevitable death, ideally embracing minimized, moderated, or eliminated pain, anxiety, suffering, loss of dignity, or distress. [...]

Objectives: Recent results of the U.S. Oncology Adjuvant Trial 9735 demonstrated significant disease-free survival and overall survival benefits for docetaxel and cyclophosphamide (TC) compared with doxorubicin and cyclophosphamide (AC) in the adjuva...

Purpose: In-the-field projects aiming to improve quality in cancer control provide a valuable complement to health services and knowledge translation (KT) research studies. The present paper describes the methods used to develop the Knowledge Transla...

Three large randomized clinical trials have shown a survival benefit in women with stage III epithelial ovarian cancer (ECO) who receive intraperitoneal (IP) chemotherapy after optimal primary debulking surgery. The most recent Gynecologic Oncology G...

Second malignancies are known to be associated with chronic lymphocytic leukemia (CLL). [...]

Multiple primary neoplasms with synchronous or metachronous presentation are rare, although the incidence has recently increased because of several factors. We present the case of a 53-year-old patient with chronic hepatitis B who presented with abdo...

Euthanasia or assisted suicide—and sometimes both—have been legalized in a small number of countries and states. In all jurisdictions, laws and safeguards were put in place to prevent abuse and misuse of these practices. Prevention measures have incl...

Purpose: Cancer survivorship is a distinct phase of the cancer continuum, and it can have myriad associated stresses and challenges. The purpose of the present study was to evaluate the effectiveness of a positive self-talk (PST) intervention in enha...

Introduction: Currently marketed epidermal growth factor receptor inhibitors (EGFRIS) have been associated with high rates of dermatologic toxicity. Methods: We formally reviewed the literature at MEDLINE and EMBASE. Additional searches were conducte...

Background: In patients with advanced gastroesophageal cancer, the phase III Randomized ECF for Advanced and Locally Advanced Esophagogastric Cancer 2 (REAL-2) trial demonstrated equivalent clinical efficacy when capecitabine (x) was substituted for...

Chronic myeloid leukemia (CML) results from expression of the constitutive tyrosine kinase activity of the Bcr-Abl oncoprotein. Imatinib, a tyrosine kinase inhibitor (TKI), is highly effective in the treatment of cml. However, some patients treated w...

Cancer dissemination to peritoneal surfaces was, in the past, a lethal condition with a limited survival. Clinical and pharmacologic research have shown that options for both treatment and prevention are now reality. The diseases most commonly treate...

The increased risk of thrombosis in patients with active cancer has multiple causes. Acute thrombosis of the aorta is an exceedingly rare but potentially devastating complication in patients with cancer receiving cisplatin-based chemotherapy. Prompt...

In one of two manuscripts in this issue (Biomedical Ethics section), Dr. Jose Pereira from the University of Ottawa presents a fascinating review of the experience of the Benelux countries in their handling of euthanasia and physician-assisted suicid...