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Cardiovascular Medicine
Volume 23
Issue 2
10.4414/cvm.2020.02098
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Cardiovascular Medicine is published by MDPI from Volume 28 Issue 1 (2025). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Editores Medicorum Helveticorum (EMH).
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Article

Patients with Syncope Remaining Unexplained After a Structured Work-Up Share the Characteristics of Patients with Neurally Mediated Syncope

by
Laurent Froidevaux
1,2,*,
François P. Sarasin
3,4,
Olivier Hugli
5,6,
Juan M. Sztajzel
4,7,
Jürg Schläpfer
1,6,
Monica Varcher-Herrera
3,
Johan Graz
3,4,
Christophe Berchier
5,6,
Mischler Corinne
1,5 and
Etienne Pruvot
1,6
1
Unité des Troubles du Rythme, Service de Cardiologie, Département Coeur-Vaisseaux, Lausanne University Hospital, Lausanne, Switzerland
2
HFR Hôpital de Riaz, Rue de l’hôpital 9, Case Postale 70, CH-1632 Riaz, Switzerland
3
Emergency Department, Hôpital Cantonal, University of Geneva Medical School, Geneva, Switzerland
4
Department of Internal Medicine, Hôpital Cantonal, University of Geneva Medical School, Geneva, Switzerland
5
Emergency Department, University hospital of Lausanne, Lausanne, Switzerland
6
Department of Internal Medicine, CHUV, Lausanne, Switzerland
7
Division of Cardiology, Hôpital Cantonal, University of Geneva Medical School, Geneva, Switzerland
*
Author to whom correspondence should be addressed.
Cardiovasc. Med. 2020, 23(2), w02098; https://doi.org/10.4414/cvm.2020.02098
Submission received: 20 January 2020 / Revised: 20 February 2020 / Accepted: 20 March 2020 / Published: 20 April 2020
Versions Notes

Abstract

Syncope is a common symptom in emergency department visits and, despite extensive evaluation, still remains unexplained in a significant number of cases. Our study compared the clinical characteristics of patients with syncope of unexplained aetiology (SUA) with those of patients with other causes of syncope after the application of a standardised work-up. Recurrence and death rates were also evaluated at one year. We found that patients with SUA shared most of the clinical and paraclinical characteristics of patients with neurally mediated syncope. During followup, recurrences occurred essentially in the SUA group. These findings support the concept that patients with SUA suffer from some form of neurally mediated syncope.
Keywords: unexplained syncope; neurally mediated syncope; standardised stepwise diagnostic work-up; death; recurrence unexplained syncope; neurally mediated syncope; standardised stepwise diagnostic work-up; death; recurrence

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MDPI and ACS Style

Froidevaux, L.; Sarasin, F.P.; Hugli, O.; Sztajzel, J.M.; Schläpfer, J.; Varcher-Herrera, M.; Graz, J.; Berchier, C.; Corinne, M.; Pruvot, E. Patients with Syncope Remaining Unexplained After a Structured Work-Up Share the Characteristics of Patients with Neurally Mediated Syncope. Cardiovasc. Med. 2020, 23, w02098. https://doi.org/10.4414/cvm.2020.02098

AMA Style

Froidevaux L, Sarasin FP, Hugli O, Sztajzel JM, Schläpfer J, Varcher-Herrera M, Graz J, Berchier C, Corinne M, Pruvot E. Patients with Syncope Remaining Unexplained After a Structured Work-Up Share the Characteristics of Patients with Neurally Mediated Syncope. Cardiovascular Medicine. 2020; 23(2):w02098. https://doi.org/10.4414/cvm.2020.02098

Chicago/Turabian Style

Froidevaux, Laurent, François P. Sarasin, Olivier Hugli, Juan M. Sztajzel, Jürg Schläpfer, Monica Varcher-Herrera, Johan Graz, Christophe Berchier, Mischler Corinne, and Etienne Pruvot. 2020. "Patients with Syncope Remaining Unexplained After a Structured Work-Up Share the Characteristics of Patients with Neurally Mediated Syncope" Cardiovascular Medicine 23, no. 2: w02098. https://doi.org/10.4414/cvm.2020.02098

APA Style

Froidevaux, L., Sarasin, F. P., Hugli, O., Sztajzel, J. M., Schläpfer, J., Varcher-Herrera, M., Graz, J., Berchier, C., Corinne, M., & Pruvot, E. (2020). Patients with Syncope Remaining Unexplained After a Structured Work-Up Share the Characteristics of Patients with Neurally Mediated Syncope. Cardiovascular Medicine, 23(2), w02098. https://doi.org/10.4414/cvm.2020.02098

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