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Marine Drugs, Volume 10, Issue 5

May 2012 - 16 articles

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Articles (16)

  • Article
  • Open Access
27 Citations
8,606 Views
10 Pages

Woodylides A–C, New Cytotoxic Linear Polyketides from the South China Sea Sponge Plakortis simplex

  • Hao-Bing Yu,
  • Xiang-Fang Liu,
  • Ying Xu,
  • Jian-Hong Gan,
  • Wei-Hua Jiao,
  • Yang Shen and
  • Hou-Wen Lin

7 May 2012

Three new polyketides, woodylides A–C (1–3), were isolated from the ethanol extract of the South China Sea sponge Plakortis simplex. The structures were elucidated by spectroscopic data (IR, 1D and 2D NMR, and HRESIMS). The absolute configurations at...

  • Article
  • Open Access
29 Citations
7,863 Views
7 Pages

7 May 2012

Chemical investigation of the cave sponge Xestospongia sp. resulted in the isolation of three new polyacetylenic long chain compounds along with two known metabolites. The structures of the new metabolites were established by NMR and MS analyses. The...

  • Article
  • Open Access
23 Citations
7,056 Views
8 Pages

Briacavatolides A–C, New Briaranes from the Taiwanese Octocoral Briareum excavatum

  • Tsun-Tai Yeh,
  • Shang-Kwei Wang,
  • Chang-Feng Dai and
  • Chang-Yih Duh

2 May 2012

In order to search for novel bioactive substances from marine organisms, we have investigated the organic extracts of the Taiwanese octocoral Briareum excavatum collected at Orchid Island. Three new briarane-type diterpenoids, briacavatolides A–C (1–...

  • Article
  • Open Access
44 Citations
10,838 Views
11 Pages

Cytotoxic Sesterterpenoids from a Sponge Hippospongia sp.

  • Yu-Chia Chang,
  • Shang-Wei Tseng,
  • Li-Lian Liu,
  • Yalan Chou,
  • Yuan-Shing Ho,
  • Mei-Chin Lu and
  • Jui-Hsin Su

27 April 2012

One new pentacyclic sesterterpene, hippospongide A (1), and one new scalarane sesterterpenoid, hippospongide B (2), along with six previously reported known scalarane–type sesterterpenes (3–8), were isolated from a sponge Hippospongia sp. The structu...

  • Article
  • Open Access
48 Citations
11,489 Views
21 Pages

Dietary Carotenoids Regulate Astaxanthin Content of Copepods and Modulate Their Susceptibility to UV Light and Copper Toxicity

  • Maria-José Caramujo,
  • Carla C. C. R. De Carvalho,
  • Soraya J. Silva and
  • Kevin R. Carman

27 April 2012

High irradiation and the presence of xenobiotics favor the formation of reactive oxygen species in marine environments. Organisms have developed antioxidant defenses, including the accumulation of carotenoids that must be obtained from the diet. Asta...

  • Review
  • Open Access
253 Citations
20,754 Views
24 Pages

Bioactive Peptides and Depsipeptides with Anticancer Potential: Sources from Marine Animals

  • Guadalupe-Miroslava Suarez-Jimenez,
  • Armando Burgos-Hernandez and
  • Josafat-Marina Ezquerra-Brauer

26 April 2012

Biologically active compounds with different modes of action, such as, antiproliferative, antioxidant, antimicrotubule, have been isolated from marine sources, specifically algae and cyanobacteria. Recently research has been focused on peptides from...

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Mar. Drugs - ISSN 1660-3397