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Medicina, Volume 59, Issue 1

January 2023 - 183 articles

Cover Story: Cardiothoracic surgical critical care medicine (CT-CCM) is an inseparable component of any successful cardiothoracic surgical program. The demand for services provided by CT-CCM is projected to increase as the population grows older and sicker. With these trends in mind, it is important to evaluate the current state of CT-CCM. Here, we propose a set of principles that we find essential to the advancement of CT-CCM as a science and identify existing knowledge gaps in the field. View this paper
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Articles (183)

  • Review
  • Open Access
8 Citations
5,700 Views
8 Pages
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International Consensus on Definition of Mild-to-Moderate Ulcerative Colitis Disease Activity in Adult Patients

  • Bénédicte Caron,
  • Vipul Jairath,
  • Ferdinando D’Amico,
  • Sameer Al Awadhi,
  • Axel Dignass,
  • Ailsa L. Hart,
  • Taku Kobayashi,
  • Paulo Gustavo Kotze,
  • Fernando Magro and
  • Britta Siegmund
  • + 3 authors
Medicina2023, 59(1), 183;https://doi.org/10.3390/medicina59010183

16 January 2023

Background and Objectives: At present, there is no consensus definition of mild-to-moderate disease activity in patients with ulcerative colitis. The objective of the present study was to establish a reliable definition of mild-to-moderate disease ac...

Full Article
  • Systematic Review
  • Open Access
6 Citations
5,918 Views
18 Pages
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Auricular Acupressure for Dry Eye Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

  • Qiong Huang,
  • Mengqi Zhan and
  • Zhe Hu
Medicina2023, 59(1), 177;https://doi.org/10.3390/medicina59010177

16 January 2023

Background and Objectives: The purpose of this systematic review was to summarize the current evidence to examine the safety and effectiveness of auricular acupressure on dry eye diseases. Materials and Methods: Twenty databases were searched from th...

Full Article
  • Review
  • Open Access
39 Citations
7,430 Views
13 Pages
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Clinical Inertia in the Management of Type 2 Diabetes Mellitus: A Systematic Review

  • Turky H. Almigbal,
  • Sarah A. Alzarah,
  • Flwah A. Aljanoubi,
  • Nouryah A. Alhafez,
  • Munirah R. Aldawsari,
  • Zahraa Y. Alghadeer and
  • Abdullah A. Alrasheed
Medicina2023, 59(1), 182;https://doi.org/10.3390/medicina59010182

16 January 2023

This review seeks to establish, through the recent available literature, the prevalence of therapeutic intensification delay and its sequences in poorly controlled Type 2 Diabetes Mellitus (T2DM) patients. The strategy identified studies exploring th...

Full Article
  • Article
  • Open Access
1 Citations
3,538 Views
11 Pages
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A Real-World Cost-Effectiveness Analysis of Rivaroxaban versus Vitamin K Antagonists for the Treatment of Symptomatic Venous Thromboembolism: Lessons from the REMOTEV Registry

  • Sabrina Kepka,
  • Elena-Mihaela Cordeanu,
  • Kevin Zarca,
  • Anne-Sophie Frantz,
  • Patrick Ohlmann,
  • Emmanuel Andres,
  • Pascal Bilbault,
  • Isabelle Durand-Zaleski and
  • Dominique Stephan
Medicina2023, 59(1), 181;https://doi.org/10.3390/medicina59010181

16 January 2023

Background and objectives: Venous thromboembolism (VTE) represents a health and economic burden with consequent healthcare resource utilization. Direct oral anticoagulants (DOACs) have emerged as the mainstay option for VTE treatment but few data exi...

Full Article
  • Article
  • Open Access
2 Citations
3,146 Views
12 Pages
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Coping with Symptoms of Mental Health Disorders among University Students during the COVID-19 Pandemic in Relation to Their Lifestyle Habits

  • Tamara Jovanović and
  • Aleksandar Višnjić
Medicina2023, 59(1), 180;https://doi.org/10.3390/medicina59010180

16 January 2023

Background and Objectives: The time of the pandemic brought great difficulties, both in state and interstate systems, industry, trade, and with individuals themselves. In addition, numerous studies have shown a drastic increase in mental disorders in...

Full Article
  • Article
  • Open Access
9 Citations
3,871 Views
13 Pages
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Relation of Maternal Pre-Pregnancy Factors and Childhood Asthma: A Cross-Sectional Survey in Pre-School Children Aged 2–5 Years Old

  • Dimitrios Papandreou,
  • Eleni Pavlidou,
  • Stefanos Tyrovolas,
  • Maria Mantzorou,
  • Eleni Andreou,
  • Evmorfia Psara,
  • Georgios Antasouras,
  • Georgios K. Vasios,
  • Efthymios Poulios and
  • Constantinos Giaginis
Medicina2023, 59(1), 179;https://doi.org/10.3390/medicina59010179

16 January 2023

Background and Objectives: Asthma constitutes a constant, prolonged, inflammation-related pulmonary disorder in childhood with serious public health concerns. Several maternal risk factors can enhance the prevalence of its development in this stage o...

Full Article
  • Article
  • Open Access
1 Citations
3,619 Views
15 Pages
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A Nonrandomized Phase 2 Trial of EG-Mirotin, a Novel, First-in-Class, Subcutaneously Deliverable Peptide Drug for Nonproliferative Diabetic Retinopathy

  • Seunghoon Yoo,
  • Dae Hyuk You,
  • Jeongyoon Lee,
  • H. Christian Hong and
  • Sung Jin Lee
Medicina2023, 59(1), 178;https://doi.org/10.3390/medicina59010178

16 January 2023

Background and objectives: EG-Mirotin (active ingredient EGT022) targets nonproliferative diabetic retinopathy (NPDR), the early stage of retinopathy. EG-Mirotin reverses capillary damage before NPDR progresses to an irreversible stage. EG-Mirotin sa...

Full Article
  • Case Report
  • Open Access
7 Citations
3,398 Views
8 Pages
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Bone Regenerative Potential of Cross-Linked Collagen Membrane in Peri-Implant Osseous Defect: Case Series with Histologic/Micro-Computed Tomographic Findings

  • Won-Bae Park,
  • Gazelle Jean Crasto,
  • Ji-Young Han,
  • Philip Kang and
  • Hyun-Chang Lim
Medicina2023, 59(1), 176;https://doi.org/10.3390/medicina59010176

15 January 2023

The role of a barrier membrane is crucial in guided bone regeneration (GBR) for space creation and cell occlusiveness. Those properties of the membrane should be sustained for a sufficient period. For such purpose, several cross-linked collagen membr...

Full Article
  • Article
  • Open Access
8 Citations
3,776 Views
10 Pages
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The Association between Burnout, Social Support, and Psychological Capital among Primary Care Providers in Togo: A Cross-Sectional Study

  • Solim Essomandan Clémence Bafei,
  • Jiaping Chen,
  • Yinan Qian,
  • Lei Yuan,
  • Yimin Zhou,
  • Muhammed Lamin Sambou,
  • Anita Nyarkoa Walker,
  • Wei Li and
  • Sijun Liu
Medicina2023, 59(1), 175;https://doi.org/10.3390/medicina59010175

15 January 2023

Background and Objectives: Job burnout is prevalent among primary care providers (PCPs) in different countries, and the factors that can alleviate burnout in these countries have been explored. However, no study has addressed the prevalence and the c...

Full Article
  • Review
  • Open Access
15 Citations
6,896 Views
21 Pages
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Phosphorus Magnetic Resonance Spectroscopy (31P MRS) and Cardiovascular Disease: The Importance of Energy

  • Vasiliki Tsampasian,
  • Donnie Cameron,
  • Rashed Sobhan,
  • George Bazoukis and
  • Vassilios S. Vassiliou
Medicina2023, 59(1), 174;https://doi.org/10.3390/medicina59010174

15 January 2023

Background and Objectives: The heart is the organ with the highest metabolic demand in the body, and it relies on high ATP turnover and efficient energy substrate utilisation in order to function normally. The derangement of myocardial energetics may...

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