You are currently viewing a new version of our website. To view the old version click .

Medicina, Volume 56, Issue 7

July 2020 - 46 articles

Cover Story: Functional dyspepsia (FD) is one of the most common gastrointestinal clinical syndromes and its etiology remains largely idiopathic. FD pharmacotherapy is difficult and often yields unsatisfactory results. Within this article, we investigate, for the first time, the efficacy and safety of trimebutine as monotherapy for FD. Trimebutine is a prokinetic drug, exhibiting also antimuscarinic and opiate receptor (mu, kappa and delta) agonist effects, as well as antibiotic properties. A multicenter, randomized, double-blind, placebo-controlled, prospective study was conducted; trimebutine was compared against placebo for a period of four weeks in patients diagnosed with FD. It was shown that trimebutine monotherapy is an effective and safe therapeutic approach for FD. This article is supplemented with additional information regarding the pathophysiology of FD and relevant additional pharmacological studies. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (46)

  • Case Report
  • Open Access
3 Citations
3,389 Views
7 Pages

21 July 2020

Rhabdomyosarcoma (RMS) is a common soft tissue sarcoma in childhood, however, it is very rare in the neonatal period (0.4–2% of cases). This case depicts a boy, who presented with RMS at two weeks of age, but officially diagnosed at the age of...

  • Article
  • Open Access
13 Citations
4,235 Views
11 Pages

21 July 2020

Background and objectives: Although treatment with novel oral non-vitamin K antagonist 3anticoagulants (NOACs) is associated with an overall decrease in hemorrhagic complications compared to warfarin, the incidence of gastrointestinal bleeding remain...

  • Review
  • Open Access
15 Citations
4,395 Views
27 Pages

The Impact of Artificial Intelligence in the Endoscopic Assessment of Premalignant and Malignant Esophageal Lesions: Present and Future

  • Daniela Cornelia Lazăr,
  • Mihaela Flavia Avram,
  • Alexandra Corina Faur,
  • Adrian Goldiş,
  • Ioan Romoşan,
  • Sorina Tăban and
  • Mărioara Cornianu

21 July 2020

In the gastroenterology field, the impact of artificial intelligence was investigated for the purposes of diagnostics, risk stratification of patients, improvement in quality of endoscopic procedures and early detection of neoplastic diseases, implem...

  • Article
  • Open Access
5 Citations
2,996 Views
10 Pages

18 July 2020

Background and Objectives: This study aimed to group diseases classified by the International Classification of Diseases using principal component analysis, and discuss a systematic approach to reducing the preventable death rate from a perspective o...

  • Article
  • Open Access
9 Citations
3,774 Views
11 Pages

18 July 2020

Background and Objectives: Dehydration might be an issue after hip fracture surgery, but the optimal tools to identify the dehydrated condition have not been determined. The aim of the present study was to compare the characteristics of elderly posto...

  • Article
  • Open Access
2 Citations
3,269 Views
13 Pages

Designers Drugs—A New Challenge to Emergency Departments—An Observational Study in Poland

  • Rakesh Jalali,
  • Paula Dmochowska,
  • Izabela Godlewska,
  • Justyna Balmas,
  • Katarzyna Młynarska,
  • Krzysztof Narkun,
  • Andrzej Zawadzki and
  • Marcin Wojnar

17 July 2020

Background and Objective: In the last decade, the phenomenon of using new psychoactive substances (NPS), called designer drugs, has been on rise. Though their production and marketing in Poland is prohibited, reports of the Supreme Audit Office noted...

  • Case Report
  • Open Access
4 Citations
3,975 Views
8 Pages

A Patient with Cryoglobulinemic Membranoproliferative GN (MPGN) Who Survived COVID-19 Disease: Case Presentation and Current Data of COVID-19 Infection in Dialysis and Transplanted Patients in Greece

  • Smaragdi Marinaki,
  • Stathis Tsiakas,
  • Chrysanthi Skalioti,
  • Panayiota Lourida,
  • Aikaterini Argyraki,
  • Konstantinos Grigorakos and
  • Ioannis Boletis

17 July 2020

The evolving pandemic of Coronavirus Disease 2019 has posed a substantial health risk worldwide. However, there is a paucity of data regarding the clinical course and the therapeutic management of patients with chronic kidney disease and COVID-19 inf...

  • Article
  • Open Access
13 Citations
5,525 Views
10 Pages

Effectiveness of 6-Week Nordic Walking Training on Functional Performance, Gait Quality, and Quality of Life in Parkinson’s Disease

  • Justyna Szefler-Derela,
  • Michal Arkuszewski,
  • Andrzej Knapik,
  • Dagmara Wasiuk-Zowada,
  • Agnieszka Gorzkowska and
  • Ewa Krzystanek

17 July 2020

Background and objectives: Motor rehabilitation improves physical mobility and quality of life in Parkinson’s disease (PD). As specialized rehabilitation is expensive and resource-consuming, there is a need for simpler, cost-effective methods....

  • Article
  • Open Access
7 Citations
3,086 Views
11 Pages

Intravenous r-tPA Dose Influence on Outcome after Middle Cerebral Artery Ischemic Stroke Treatment by Mechanical Thrombectomy

  • Marius Kurminas,
  • Andrius Berūkštis,
  • Nerijus Misonis,
  • Karmela Blank,
  • Algirdas Edvardas Tamošiūnas and
  • Dalius Jatužis

17 July 2020

Background and Objectives: Pretreatment with intravenous thrombolysis (IVT) is still recommended in all eligible acute ischemic stroke patients with large-vessel occlusion before mechanical thrombectomy (MTE). However, the added value and safety of b...

  • Article
  • Open Access
11 Citations
5,880 Views
10 Pages

17 July 2020

Background and objectives: Hypernatremia can be community or hospital-acquired, and there may be specific factors unique to the hospital environment, such as intravenous fluid treatment, which contribute to hypernatremia. The aim of this study was to...

of 5

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Medicina - ISSN 1648-9144