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Medicina, Volume 56, Issue 6

2020 June - 64 articles

Cover Story: One of the key elements for COVID-19 therapy is to properly balance and adapt the nutritional status and course of the disease immediately after admission to the department feeding the patient. In this article, we perform nutritional assessments, energy requirement calculations, and diet/supplementation compositions on patients with mild and acute COVID-19 symptoms. This article is supplemented with recommendations from the European Society for Parenteral and Enteral Nutrition concerning nutrition of people in critical condition. View this paper
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Articles (64)

  • Article
  • Open Access
13 Citations
3,136 Views
8 Pages

Lung Ultrasound and Clinical Progression of Acute Bronchiolitis: A Prospective Observational Single-Center Study

  • Antonio Di Mauro,
  • Anna Rita Cappiello,
  • Angela Ammirabile,
  • Nicla Abbondanza,
  • Francesco Paolo Bianchi,
  • Silvio Tafuri and
  • Mariano M. Manzionna

26 June 2020

Background and Objectives: Recent literature suggests that lung ultrasound might have a role in the diagnosis and management of bronchiolitis. The aim of the study is to evaluate the relationship between an ultrasound score and the clinical progressi...

  • Article
  • Open Access
6 Citations
4,035 Views
12 Pages

A Comprehensive Analysis of Clinical Trials in the COVID-19 Pandemic Era

  • Jinhee Lee,
  • Han Wul Shin,
  • Jun Young Lee,
  • Jae Seok Kim,
  • Jae Won Yang,
  • Keum Hwa Lee,
  • Andreas Kronbichler and
  • Jae Il Shin

26 June 2020

Background and objective: Despite medical advances, we are facing the unprecedented disaster of the coronavirus disease 2019 (COVID-19) pandemic without available treatments and effective vaccines. As the COVID-19 pandemic has approached its culminat...

  • Case Report
  • Open Access
2 Citations
3,315 Views
7 Pages

Recurrent Pheochromocytoma in an Elderly Patient

  • Ammu Thampi Susheela,
  • Howide Eldib,
  • Deepthi Vinnakota,
  • Andrea Bial,
  • Salman Ali,
  • Hannah Koh,
  • Brian Lavery and
  • Martin Gorbien

26 June 2020

Pheochromocytomas are rare neuroendocrine tumors that can affect people of all ages and are commonly diagnosed in the 4th and 5th decades of life. Familial pheochromocytomas are diagnosed mostly between the 2nd and 3rd decades of life. They can be be...

  • Article
  • Open Access
2 Citations
2,922 Views
14 Pages

Comparative Analysis of Risk Factors in Declined Kidneys from Donation after Brain Death and Circulatory Death

  • Zinah Zwaini,
  • Meeta Patel,
  • Cordula Stover,
  • John Dormer,
  • Michael L. Nicholson,
  • Sarah A. Hosgood and
  • Bin Yang

26 June 2020

Background and objectives: Kidneys from donation after circulatory death (DCD) are more likely to be declined for transplantation compared with kidneys from donation after brain death (DBD). The aim of this study was to evaluate characteristics in th...

  • Case Report
  • Open Access
9 Citations
3,322 Views
9 Pages

Combined Robotic Surgery for Double Renal Masses and Prostate Cancer: Myth or Reality?

  • Giovanni Cochetti,
  • Diego Cocca,
  • Stefania Maddonni,
  • Alessio Paladini,
  • Elena Sarti,
  • Davide Stivalini and
  • Ettore Mearini

26 June 2020

With the widespread use of imaging modalities performed for the staging of prostate cancer, the incidental detection of synchronous tumors is increasing in frequency. Robotic surgery represents a technical evolution in the treatment of solid tumors o...

  • Article
  • Open Access
32 Citations
7,379 Views
12 Pages

Patterns and Factors Associated with Self-Medication among the Pediatric Population in Romania

  • Petruța Tarciuc,
  • Ana Maria Alexandra Stanescu,
  • Camelia Cristina Diaconu,
  • Luminita Paduraru,
  • Alina Duduciuc and
  • Smaranda Diaconescu

25 June 2020

Background and objectives: Self-medication is a global phenomenon in both developed and emerging countries. At present, data regarding the practice, patterns, and factors associated with self-medication in Romanian patient groups of various ages and...

  • Article
  • Open Access
14 Citations
4,123 Views
11 Pages

25 June 2020

Many athletic governing bodies are adopting on-site measurement of the wet-bulb globe temperature (WBGT) as part of their heat safety policies. It is well known, however, that microclimatic conditions can vary over different surface types and a quest...

  • Article
  • Open Access
13 Citations
3,642 Views
11 Pages

Prognostic Factors for All-Cause Mortality in Thai Patients with Fragility Fracture of Hip: Comorbidities and Laboratory Evaluations

  • Pichitchai Atthakomol,
  • Worapaka Manosroi,
  • Phichayut Phinyo,
  • Tanyong Pipanmekaporn,
  • Tanawat Vaseenon and
  • Sattaya Rojanasthien

24 June 2020

Background and Objectives: Although the types of comorbidities and laboratory evaluations are major factors associated with mortality after hip fractures, there have been no studies of the association of these factors and mortality in Thai hip-fractu...

  • Article
  • Open Access
5 Citations
3,616 Views
13 Pages

Association between Osteoporosis and Cognitive Impairment during the Acute and Recovery Phases of Ischemic Stroke

  • Sang-Hwa Lee,
  • So Young Park,
  • Min Uk Jang,
  • Yerim Kim,
  • Jungyoup Lee,
  • Chulho Kim,
  • Yeo Jin Kim and
  • Jong-Hee Sohn

23 June 2020

Background and objectives: Little is known about the effect of osteoporosis on cognitive function in the acute and recovery phases of stroke. Early bone mineral density assessments during acute stroke may be a useful marker of cognitive function. We...

  • Article
  • Open Access
36 Citations
6,310 Views
15 Pages

Rates of Intracranial Hemorrhage in Mild Head Trauma Patients Presenting to Emergency Department and Their Management: A Comparison of Direct Oral Anticoagulant Drugs with Vitamin K Antagonists

  • Gabriele Savioli,
  • Iride Francesca Ceresa,
  • Sabino Luzzi,
  • Cristian Gragnaniello,
  • Alice Giotta Lucifero,
  • Mattia Del Maestro,
  • Stefano Marasco,
  • Federica Manzoni,
  • Luca Ciceri and
  • Maria Antonietta Bressan
  • + 2 authors

23 June 2020

Background and objectives: Anticoagulants are thought to increase the risks of traumatic intracranial injury and poor clinical outcomes after blunt head trauma. The safety of using direct oral anticoagulants (DOACs) compared to vitamin K antagonists...

  • Review
  • Open Access
57 Citations
19,644 Views
26 Pages

Oral Administration of Cannabis and Δ-9-tetrahydrocannabinol (THC) Preparations: A Systematic Review

  • Lourdes Poyatos,
  • Ana Pilar Pérez-Acevedo,
  • Esther Papaseit,
  • Clara Pérez-Mañá,
  • Soraya Martin,
  • Olga Hladun,
  • Adrià Siles,
  • Marta Torrens,
  • Francesco Paolo Busardo and
  • Magí Farré

23 June 2020

Background and objective: Changes in cannabis legalization regimes in several countries have influenced the diversification of cannabis use. There is an ever-increasing number of cannabis forms available, which are gaining popularity for both recreat...

  • Article
  • Open Access
5 Citations
7,871 Views
13 Pages

Evaluation of Surgical Treatment of Oroantral Fistulae in Smokers Versus Non-Smokers

  • Adi Sella,
  • Yehonatan Ben-Zvi,
  • Leon Gillman,
  • Gal Avishai,
  • Gavriel Chaushu and
  • Eli Rosenfeld

23 June 2020

Background and Objectives: Smoking has been found to interfere with wound healing processes. Therefore, the purpose of this study was to compare surgical treatment of oroantral fistulae (OAFs) in smokers and non-smokers. Materials and Methods: Medica...

  • Case Report
  • Open Access
57 Citations
6,938 Views
9 Pages

Report of Positive Placental Swabs for SARS-CoV-2 in an Asymptomatic Pregnant Woman with COVID-19

  • Antonella Ferraiolo,
  • Fabio Barra,
  • Chiara Kratochwila,
  • Michele Paudice,
  • Valerio Gaetano Vellone,
  • Elisabetta Godano,
  • Serena Varesano,
  • Giovanni Noberasco,
  • Simone Ferrero and
  • Cesare Arioni

22 June 2020

Currently, limited data on maternal and neonatal outcomes of pregnant women with infection and pneumonia related to SARS coronavirus 2 (SARS-CoV-2) are available. Our report aims to describe a case of placental swabs positive for the molecular resear...

  • Article
  • Open Access
9 Citations
2,703 Views
9 Pages

Global Longitudinal Strain of the Systemic Ventricle Is Correlated with Plasma Galectin-3 and Predicts Major Cardiovascular Events in Adult Patients with Congenital Heart Disease

  • Alexandra A. Frogoudaki,
  • Ioannis Pantelakis,
  • Vasiliki Bistola,
  • Christos Kroupis,
  • Dionysia Birba,
  • Ignatios Ikonomidis,
  • Dimitrios Alexopoulos,
  • Gerasimos Filippatos and
  • John Parissis

22 June 2020

Backround and Objective: We sought to assess in adult congenital heart disease (ACHD) patients the prognostic value of plasma galectin-3 (Gal-3) levels and systemic ventricular global longitudinal strain (SV GLS) as well as their association with NTp...

  • Article
  • Open Access
3 Citations
2,667 Views
12 Pages

Right Ventricle Mechanics and Function during Stress in Patients with Asymptomatic Primary Moderate to Severe Mitral Regurgitation and Preserved Left Ventricular Ejection Fraction

  • Rūta Žvirblytė,
  • Ieva Merkytė,
  • Eglė Tamulėnaitė,
  • Agnė Saniukaitė,
  • Vaida Mizarienė,
  • Eglė Ereminienė and
  • Jolanta Justina Vaškelytė

20 June 2020

Background and objectives. Mitral regurgitation (MR) is usually dynamic and increasing with exertion. Stress may provoke symptoms, cause the progression of pulmonary hypertension (PH) and unmask subclinical changes of the left and right ventricle fun...

  • Article
  • Open Access
2 Citations
4,532 Views
9 Pages

20 June 2020

To evaluate the cervical-vaginal mucin, CA125, as a measure of fertility and possible method for natural family planning (NFP). Cervical-vaginal fluid (CVF) swab samples have been previously used to measure CA125, ‘Qvaginal CA125 levels’,...

  • Review
  • Open Access
35 Citations
6,577 Views
18 Pages

Risk Factors and Management of Osteoporosis Post-Transplant

  • Karthik Kovvuru,
  • Swetha Rani Kanduri,
  • Pradeep Vaitla,
  • Rachana Marathi,
  • Shiva Gosi,
  • Desiree F. Garcia Anton,
  • Franco H. Cabeza Rivera and
  • Vishnu Garla

19 June 2020

Bone and mineral disorders are common after organ transplantation. Osteoporosis post transplantation is associated with increased morbidity and mortality. Pathogenesis of bone disorders in this particular sub set of the population is complicated by m...

  • Article
  • Open Access
4 Citations
4,519 Views
10 Pages

Can the Computed Tomographic Aspect of Porto-Systemic Circulation in Cirrhotic Patients Be Associated with the Presence of Variceal Hemorrhage?

  • Cosmin Caraiani,
  • Bianca Petresc,
  • Anamaria Pop,
  • Magda Rotaru,
  • Lidia Ciobanu and
  • Horia Ștefănescu

19 June 2020

Background and objectives: Variceal bleeding is a serious complication caused by portal hypertension, frequently encountered among cirrhotic patients. The purpose of this study was to determine whether the aspect of the collateral, porto-systemic cir...

  • Review
  • Open Access
35 Citations
4,550 Views
16 Pages

B-Cell Lymphoma 2 (Bcl-2) and Regulation of Apoptosis after Traumatic Brain Injury: A Clinical Perspective

  • Hansen Deng,
  • John K. Yue,
  • Benjamin E. Zusman,
  • Enyinna L. Nwachuku,
  • Hussam Abou-Al-Shaar,
  • Pavan S. Upadhyayula,
  • David O. Okonkwo and
  • Ava M. Puccio

18 June 2020

Background and Objectives: The injury burden after head trauma is exacerbated by secondary sequelae, which leads to further neuronal loss. B-cell lymphoma 2 (Bcl-2) is an anti-apoptotic protein and a key modulator of the programmed cell death (PCD) p...

  • Article
  • Open Access
5 Citations
3,380 Views
9 Pages

Tumor Suppressors—HTRA Proteases and Interleukin-12—in Pediatric Asthma and Allergic Rhinitis Patients

  • Joanna Renke,
  • Eliza Wasilewska,
  • Sabina Kędzierska-Mieszkowska,
  • Katarzyna Zorena,
  • Sylwia Barańska,
  • Tomasz Wenta,
  • Anna Liberek,
  • Danuta Siluk,
  • Dorota Żurawa-Janicka and
  • Barbara Lipińska
  • + 2 authors

17 June 2020

Background and objective: Allergy belongs to a group of mast cell-related disorders and is one of the most common diseases of childhood. It was shown that asthma and allergic rhinitis diminish the risk of various cancers, including colon cancer and a...

  • Review
  • Open Access
10 Citations
6,377 Views
11 Pages

Lactation Ketoacidosis: A Systematic Review of Case Reports

  • Abdullah M. Al Alawi,
  • Asma Al Flaiti and
  • Henrik Falhammar

17 June 2020

Background and Objective: Lactation ketoacidosis is a rare cause of high anion gap metabolic acidosis affecting breastfeeding mothers. We aim to review and analyze all cases of lactation ketoacidosis reported. Materials and Methods: A systematic sear...

  • Article
  • Open Access
5 Citations
2,999 Views
13 Pages

Residual Pulmonary Hypertension More than 20 Years after Repair of Shunt Lesions

  • Dovilė Jančauskaitė,
  • Virginija Rudienė,
  • Gabrielius Jakutis,
  • Laurie W Geenen,
  • Jolien W Roos-Hesselink and
  • Lina Gumbienė

16 June 2020

Background and Objectives: After successful surgical repair of a congenital shunt lesion, pulmonary hypertension (PH) often disappears. However, PH can persist long-term after the closure. This study aimed to assess the prevalence of PH long-term aft...

  • Communication
  • Open Access
36 Citations
4,804 Views
12 Pages

Who Consult an Adult Psychiatric Emergency Department? Pertinence of Admissions and Opportunities for Telepsychiatry

  • Alessandra Costanza,
  • Viridiana Mazzola,
  • Michalina Radomska,
  • Andrea Amerio,
  • Andrea Aguglia,
  • Paco Prada,
  • Guido Bondolfi,
  • François Sarasin and
  • Julia Ambrosetti

13 June 2020

Background and Objectives: Psychiatric disorders constitute frequent causes of emergency department (ED) admissions and these rates are increasing. However, referring to ED a whole range of conditions that could or should be dealt with elsewhere is i...

  • Protocol
  • Open Access
44 Citations
9,821 Views
14 Pages

Nutritional Support in Coronavirus 2019 Disease

  • Ewa Stachowska,
  • Marcin Folwarski,
  • Dominika Jamioł-Milc,
  • Dominika Maciejewska and
  • Karolina Skonieczna-Żydecka

12 June 2020

The epidemic that broke out in Chinese Wuhan at the beginning of 2020 presented how important the rapid diagnosis of malnutrition (elevating during intensive care unit stay) and the immediate implementation of caloric and protein-balanced nutrition c...

  • Article
  • Open Access
11 Citations
4,530 Views
11 Pages

Dropped Head Syndrome Attenuation by Hybrid Assistive Limb: A Preliminary Study of Three Cases on Cervical Alignment during Walking

  • Hideki Kadone,
  • Kousei Miura,
  • Shigeki Kubota,
  • Tetsuya Abe,
  • Yukiyo Shimizu,
  • Yasushi Hada,
  • Kenji Suzuki,
  • Yoshiyuki Sankai,
  • Masao Koda and
  • Masashi Yamazaki

12 June 2020

Background and Objectives: Dropped head syndrome (DHS) is characterized by apparent neck extensor muscle weakness and difficulty in extending the neck to raise the head against gravity. DHS affects forward vision and eating behavior, and hence impair...

  • Case Report
  • Open Access
14 Citations
4,048 Views
10 Pages

Effective Preoperative Plasmapheresis Treatment of Severe Hyperthyroidism in a Patient with Giant Toxic Nodular Goiter and Methimazole-Induced Agranulocytosis

  • Katarzyna Barwinek,
  • Danuta Gąsior-Perczak,
  • Sławomir Trepka,
  • Artur Szczodry,
  • Janusz Kopczyński,
  • Zdzisława Sitarz-Żelazna and
  • Aldona Kowalska

12 June 2020

Agranulocytosis is a rare but very serious complication of thyrostatic therapy. In severe hyperthyroidism, the removal of circulating thyroid hormones by plasmapheresis may be an effective therapeutic option. This report describes the therapeutic dif...

  • Article
  • Open Access
28 Citations
9,357 Views
11 Pages

Acute Effects of a Heat-Not-Burn Tobacco Product on Pulmonary Function

  • Athanasia Pataka,
  • Seraphim Kotoulas,
  • Evangelos Chatzopoulos,
  • Ioanna Grigoriou,
  • Konstantinos Sapalidis,
  • Christoforos Kosmidis,
  • Anastasios Vagionas,
  • Εleni-Isidora Perdikouri,
  • Konstantinos Drevelegas and
  • Paraskevi Argyropoulou
  • + 1 author

12 June 2020

Background and objectives: During the last decade, conventional tobacco smoking is experiencing a decline and new smoking products have been introduced. IQOS (“I-Quit-Ordinary-Smoking”) is a type of “heat-not-burn” (HNB) tobac...

  • Article
  • Open Access
37 Citations
10,223 Views
11 Pages

Ectopic Cervical Pregnancy: Treatment Route

  • Guglielmo Stabile,
  • Francesco Paolo Mangino,
  • Federico Romano,
  • Giulia Zinicola and
  • Giuseppe Ricci

12 June 2020

Background and objectives: Cervical pregnancy (CP) is a rare form of ectopic pregnancy (EP) in which the embryo implants and grows inside the endocervical canal. Early diagnosis is essential in order to allow conservative medical and surgical treatme...

  • Opinion
  • Open Access
17 Citations
5,249 Views
10 Pages

12 June 2020

As a result of the ongoing 2019 coronavirus disease (COVID-19) pandemic, the medical and dental services across the world have to tackle unprecedented situations, providing essential care and professional support. The global health care crisis caused...

  • Review
  • Open Access
16 Citations
3,458 Views
9 Pages

Incidence of Prostate Cancer in Inflammatory Bowel Disease: A Meta-Analysis

  • Edoardo Carli,
  • Gian Paolo Caviglia,
  • Rinaldo Pellicano,
  • Sharmila Fagoonee,
  • Stefano Rizza,
  • Marco Astegiano,
  • Giorgio Maria Saracco and
  • Davide Giuseppe Ribaldone

11 June 2020

Background and objectives: Inflammatory bowel disease (IBD) is associated with an increased risk of developing colorectal cancer as well as some extra-intestinal tumors, but there are still limited data about the risk of prostate cancer (PC). To anal...

  • Article
  • Open Access
3 Citations
2,389 Views
6 Pages

Oral Health-Related Quality of Life in People with Achalasia

  • Marcel Hanisch,
  • Sabrina Wiemann,
  • Lauren Bohner,
  • Susanne Jung,
  • Johannes Kleinheinz and
  • Sebastian Igelbrink

11 June 2020

Background and Objective: The oral health-related quality of life (OHRQoL) of patients with achalasia has not been evaluated to date. Therefore, the aim of this study was to assess the OHRQoL of patients with achalasia and to get information about th...

  • Article
  • Open Access
8 Citations
3,791 Views
14 Pages

Analysis of Diabetes Mellitus-Related Amputations in the State of Espírito Santo, Brazil

  • Wendel Jose Teixeira Costa,
  • Nilson Penha-Silva,
  • Italla Maria Pinheiro Bezerra,
  • Ismar Paulo dos Santos,
  • José Lucas Souza Ramos,
  • Jonathan Mendes de Castro,
  • Júlio Eduardo Gomes Pereira,
  • Alan Patrício da Silva,
  • Adilson Monteiro and
  • Luiz Carlos de Abreu

11 June 2020

Background and objectives: Diabetes mellitus (DM) stands out among the most important public health problems worldwide since it represents a high burden on health systems and is associated with higher hospitalization rates, and a higher incidence of...

  • Article
  • Open Access
7 Citations
3,190 Views
14 Pages

Risk Factors for Delayed Neurocognitive Recovery According to Brain Biomarkers and Cerebral Blood Flow Velocity

  • Rasa Bukauskienė,
  • Edmundas Širvinskas,
  • Tadas Lenkutis,
  • Rimantas Benetis and
  • Rasa Steponavičiūtė

11 June 2020

Background and Objectives: The aim of this study is to identify risk factors for the development of delayed neurocognitive recovery (dNCR). Materials and Methods: 140 patients underwent neurocognitive evaluations (Adenbrooke, MoCa, trial making, and...

  • Case Report
  • Open Access
4 Citations
6,126 Views
6 Pages

Angiolipoma in the Head and Neck: Imaging, Diagnosis and Management

  • Vadim Reiser,
  • Bahaa Haj Yahya,
  • Gavriel Chaushu,
  • Ilana Kaplan and
  • Yafit Hamzani

10 June 2020

Angiolipoma, distinguishable from other lipomas by its excessive degree of vascular vessels, are rare in the head and neck and require unique management. A slow growing mass, located underneath the inferior border of the right mandibular angle of a 5...

  • Review
  • Open Access
17 Citations
6,259 Views
11 Pages

Kidney Transplant in Fabry Disease: A Revision of the Literature

  • Irene Capelli,
  • Valeria Aiello,
  • Lorenzo Gasperoni,
  • Giorgia Comai,
  • Valeria Corradetti,
  • Matteo Ravaioli,
  • Elena Biagini,
  • Claudio Graziano and
  • Gaetano La Manna

10 June 2020

Fabry disease is classified as a rare X-linked disease caused by a complete or partial defect of enzyme alpha-galactosidase, due to GLA gene mutations. This disorder leads to intracellular globotriaosylceramide (Gb3) deposition associated with increa...

  • Article
  • Open Access
1 Citations
3,752 Views
12 Pages

Reduced Stroke Risk among Patients with Atrial Fibrillation Receiving Chinese Herbal Medicines Treatment: Analysis of Domestic Data in Taiwan

  • Li-Cheng Zheng,
  • Hanoch Livneh,
  • Wei-Jen Chen,
  • Miao-Chiu Lin,
  • Ming-Chi Lu,
  • Chia-Chou Yeh and
  • Tzung-Yi Tsai

Background and objectives: Patients with atrial fibrillation (AF) reportedly have a much higher risk of death due to stroke. Faced with this heavy burden, it remains unclear if the Chinese herbal medicines (CHMs), the most common form complementary a...

  • Article
  • Open Access
18 Citations
2,872 Views
10 Pages

Disparities in Access to Autologous Breast Reconstruction

  • David J. Restrepo,
  • Maria T. Huayllani,
  • Daniel Boczar,
  • Andrea Sisti,
  • Minh-Doan T. Nguyen,
  • Jordan J. Cochuyt,
  • Aaron C. Spaulding,
  • Brian D. Rinker,
  • Galen Perdikis and
  • Antonio J. Forte

Background and objectives: This study aimed to determine if age, race, region, insurance, and comorbidities affect the type of breast reconstruction that patients receive. Materials and methods: This analysis used the Florida Inpatient Discharge Data...

  • Protocol
  • Open Access
12 Citations
2,840 Views
9 Pages

Long-Term Outcomes in Patients with Stroke after in-Hospital Treatment—Study Protocol of the Prospective Stroke Cohort Augsburg (SCHANA Study)

  • Michael Ertl,
  • Christa Meisinger,
  • Jakob Linseisen,
  • Sebastian-Edgar Baumeister,
  • Philipp Zickler and
  • Markus Naumann

Introduction: In Germany, stroke is the third leading cause of death, with more than 60,000 fatalities out of approximately 260,000 cases (first-ever and recurrent strokes) each year. So far, there are only a few long-term studies investigating deter...

  • Article
  • Open Access
9 Citations
3,679 Views
11 Pages

Effectiveness of a Real-Time Ventilation Feedback Device for Guiding Adequate Minute Ventilation: A Manikin Simulation Study

  • Sejin Heo,
  • Sun Young Yoon,
  • Jongchul Kim,
  • Hye Seung Kim,
  • Kyunga Kim,
  • Hee Yoon,
  • Sung Yeon Hwang,
  • Won Chul Cha and
  • Taerim Kim

Background and objectives: It is often challenging even for skilled rescuers to provide adequate positive pressure ventilation consistently. This study aimed to investigate the effectiveness of a newly developed real-time ventilation feedback device...

  • Article
  • Open Access
11 Citations
4,121 Views
10 Pages

Diagnosis Accuracy of Carpal Tunnel Syndrome in Diabetic Neuropathy

  • Nicu Cătălin Drăghici,
  • Maria Magdalena Tămaș,
  • Daniel Corneliu Leucuța,
  • Tudor Dimitrie Lupescu,
  • Ștefan Strilciuc,
  • Simona Rednic and
  • Dafin Fior Mureșanu

Background and objectives: Carpal tunnel syndrome (CTS) is a common pathology, but sometimes the diagnosis is delayed in patients with diabetic neuropathy (DN). The aim of the study is twofold: first, to compare the accuracy of ultrasound (US) with t...

  • Article
  • Open Access
24 Citations
3,206 Views
8 Pages

Background and Objectives: assessment systems, such as the Sequential Organ Failure Assessment (SOFA) scale, are routinely used in intensive care units (ICUs) worldwide in order to predict patients’ outcome. We aimed to investigate SOFA’s...

  • Article
  • Open Access
19 Citations
4,030 Views
11 Pages

Background and Objectives: Skeletal muscles are considered to be the main source of circulating irisin, both at rest and during physical activity. The aim of this study was to investigate the connection between irisin, body composition, and energy me...

  • Review
  • Open Access
6 Citations
3,091 Views
17 Pages

A Six-Year Analysis of Biological Therapy for Severe Psoriasis in a Lithuanian Reference Centre of Dermatovenereology

  • Tadas Raudonis,
  • Akvile Gliebute,
  • Anna Greta Grigaityte,
  • Zivile Lukosiunaite,
  • Tatjana Karmaziene and
  • Jurate Grigaitiene

Background and Objectives: Biological therapy is widely used for the treatment of severe psoriasis. The objective of this study was to evaluate the efficacy and safety of biological therapy for patients with severe psoriasis. Materials and Methods: A...

  • Article
  • Open Access
9 Citations
3,492 Views
8 Pages

Background and Objectives: Acne, an inflammatory disorder of the pilosebaceous unit associated with both physiological and psychological morbidities, should be considered a chronic disease. The application of self-regulation theory and therapeutic pa...

  • Case Report
  • Open Access
8 Citations
3,546 Views
7 Pages

Acute Disseminated Encephalomyelitis with Seizures and Myocarditis: A Fatal Triad

  • Hanne Lademann,
  • Astrid Bertsche,
  • Axel Petzold,
  • Fred Zack,
  • Andreas Büttner,
  • Jan Däbritz,
  • Christina Hauenstein,
  • Erik Bahn,
  • Christian Spang and
  • Johannes Ehler
  • + 2 authors

Autoimmune pathology of acute disseminated encephalomyelitis (ADEM) is generally restricted to the brain. Our objective is to expand the phenotype of ADEM. A four-year-old girl was admitted to the pediatric emergency room of a university medical cent...

  • Review
  • Open Access
160 Citations
9,742 Views
17 Pages

Periodontitis, Low-Grade Inflammation and Systemic Health: A Scoping Review

  • Gennaro Cecoro,
  • Marco Annunziata,
  • Morena Tina Iuorio,
  • Livia Nastri and
  • Luigi Guida

Background and objectives: Periodontitis is a multifactorial chronic inflammatory infectious disease in which an infection is necessary, but not sufficient, for development of the condition. Individual susceptibility strictly linked to the immune and...

  • Communication
  • Open Access
13 Citations
3,292 Views
11 Pages

Roles of JNK/Nrf2 Pathway on Hemin-Induced Heme Oxygenase-1 Activation in MCF-7 Human Breast Cancer Cells

  • Hye-Yeon Jang,
  • On-Yu Hong,
  • Eun-Yong Chung,
  • Kwang-Hyun Park and
  • Jong-Suk Kim

Heme oxygenase-1 (HO-1) is highly induced in various human disease states, including cancer, indicating that HO-1 is an emerging target of cancer therapy. In this study, we investigated that the mechanisms of hemin-induced HO-1 expression and its sig...

  • Article
  • Open Access
17 Citations
4,893 Views
21 Pages

Oxytocin Differentiated Effects According to the Administration Route in a Prenatal Valproic Acid-Induced Rat Model of Autism

  • Radu Lefter,
  • Alin Ciobica,
  • Iulia Antioch,
  • Daniela Carmen Ababei,
  • Luminita Hritcu and
  • Alina-Costina Luca

Background and objectives: The hormone oxytocin (OXT) has already been reported in both human and animal studies for its promising therapeutic potential in autism spectrum disorder (ASD), but the comparative effectiveness of various administration ro...

  • Article
  • Open Access
6 Citations
4,631 Views
14 Pages

Non-Steroidal Anti-Inflammatory Drug Etoricoxib Facilitates the Application of Individualized Exercise Programs in Patients with Ankylosing Spondylitis

  • Iulia Rahela Marcu,
  • Dalia Dop,
  • Vlad Padureanu,
  • Stefan Adrian Niculescu,
  • Rodica Padureanu,
  • Carmen Elena Niculescu and
  • Otilia Constantina Rogoveanu

Background and objectives: The main objective of this study is to highlight the efficiency of different therapeutic means in patients with ankylosing spondylitis, resulting in the improvement of their quality of life. Materials and Methods: We conduc...

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Medicina - ISSN 1648-9144