You are currently viewing a new version of our website. To view the old version click .

Current Issues in Molecular Biology, Volume 46, Issue 7

July 2024 - 85 articles

Cover Story: Recurrent respiratory papillomatosis (RRP) is a benign disease of the upper aerodigestive tract caused by human papillomavirus (HPV) types 6 and 11. The molecular mechanisms of HPV infection in keratinocytes have been extensively studied throughout the years, with special attention being paid to its role in causing malignant tumors. A central role in this process is played by the vascular endothelial growth factor (VEGF), which activates different signaling cascades on multiple levels. This work summarizes current evidence about the role of VEGF in the pathophysiology of RRP, the molecular pathways activated by binding with its receptors, and the state of the art of antiangiogenic treatment. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (85)

  • Review
  • Open Access
6 Citations
2,793 Views
13 Pages

Roles of SMAD and SMAD-Associated Signaling Pathways in Nerve Regeneration Following Peripheral Nerve Injury: A Narrative Literature Review

  • Jeongmin Lee,
  • Dong Keon Yon,
  • Yong Sung Choi,
  • Jinseok Lee,
  • Joon Hyung Yeo,
  • Sung Soo Kim,
  • Jae Min Lee and
  • Seung Geun Yeo

Although several methods are being applied to treat peripheral nerve injury, a perfect treatment that leads to full functional recovery has not yet been developed. SMAD (Suppressor of Mothers Against Decapentaplegic Homolog) plays a crucial role in n...

  • Article
  • Open Access
1 Citations
1,745 Views
24 Pages

Serum Extracellular Vesicles Cargo Approach in Bitches with Mammary Tumors

  • Gabriela C. Sousa,
  • Marcos G. Carvalho,
  • Carlos E. Fonseca-Alves and
  • Fabiana F. Souza

This study investigated serum extracellular vesicles (EVs) in bitches with mammary neoplasms, in order to understand their size, shape, and concentration, as well as their association with tumor malignancy. Thirty bitches were categorized into contro...

  • Article
  • Open Access
6 Citations
2,180 Views
15 Pages

Downregulation of Splicing Factor PTBP1 Curtails FBXO5 Expression to Promote Cellular Senescence in Lung Adenocarcinoma

  • Haoyu Li,
  • Xiaoxiao Sun,
  • Yuanyuan Lv,
  • Gang Wei,
  • Ting Ni,
  • Wenxin Qin,
  • Haojie Jin and
  • Qi Jia

Polypyrimidine tract-binding protein 1 (PTBP1) plays an essential role in splicing and post-transcriptional regulation. Moreover, PTBP1 has been implicated as a causal factor in tumorigenesis. However, the involvement of PTBP1 in cellular senescence,...

  • Article
  • Open Access
4 Citations
1,718 Views
11 Pages

Inflammatory Cytokines and Clinical Outcome Following Biological Therapy in Adult Bio-Naïve Psoriasis Patients

  • Teodora-Larisa Florian,
  • Ioan-Alexandru Florian,
  • Stefan Cristian Vesa,
  • Lehel Beni and
  • Meda Orăsan

Inflammatory cytokines may hold the key to the clinical evolution of psoriasis. The aims of this study are to find a correlation between levels of inflammatory cytokines such as TNF-α, IL-23, IL-17A, and IL-17F and disease duration and severity...

  • Review
  • Open Access
2,471 Views
17 Pages

MicroRNAs Associated with IgLON Cell Adhesion Molecule Expression

  • Marco Salluzzo,
  • Clara Vianello,
  • Francesca Flotta,
  • Roberto Rimondini and
  • Lucia Carboni

The IgLON family of cell adhesion molecules consists of five members (LSAMP, OPCML, neurotrimin, NEGR1, and IgLON5) discovered as supporters of neuronal development, axon growth and guidance, and synapse formation and maintenance. Tumour suppression...

  • Article
  • Open Access
9 Citations
3,232 Views
16 Pages

The importance of decellularized extracellular matrix (dECM) as a natural biomaterial in tissue engineering and regenerative medicine is rapidly growing. The core objective of the decellularization process is to eliminate cellular components while ma...

  • Review
  • Open Access
5 Citations
13,151 Views
18 Pages

Ashwagandha-Induced Programmed Cell Death in the Treatment of Breast Cancer

  • Renata Kołodziejska,
  • Agnieszka Tafelska-Kaczmarek,
  • Mateusz Pawluk,
  • Krzysztof Sergot,
  • Lucyna Pisarska,
  • Alina Woźniak and
  • Hanna Pawluk

The aim of this review is to provide experimental evidence for the programmed-death activity of Ashwagandha (Withania somnifera) in the anti-cancer therapy of breast cancer. The literature search was conducted using online electronic databases (Googl...

  • Review
  • Open Access
10 Citations
6,907 Views
47 Pages

Targeting β-Cell Plasticity: A Promising Approach for Diabetes Treatment

  • Esmaeel Ghasemi Gojani,
  • Sweta Rai,
  • Farzaneh Norouzkhani,
  • Salma Shujat,
  • Bo Wang,
  • Dongping Li,
  • Olga Kovalchuk and
  • Igor Kovalchuk

The β-cells within the pancreas play a pivotal role in insulin production and secretion, responding to fluctuations in blood glucose levels. However, factors like obesity, dietary habits, and prolonged insulin resistance can compromise β-ce...

  • Article
  • Open Access
2 Citations
2,476 Views
27 Pages

Within the field of Philippine folkloric medicine, the utilization of indigenous plants like Euphorbia hirta (tawa-tawa), Carica papaya (papaya), and Psidium guajava (guava) as potential dengue remedies has gained attention. Yet, limited research exi...

of 9

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Curr. Issues Mol. Biol. - ISSN 1467-3045