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Correction to Int. J. Mol. Sci. 2019, 20(4), 946.
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Correction

Correction: Kim et al. Anti-Inflammatory Response and Muscarinic Cholinergic Regulation During the Laxative Effect of Asparagus cochinchinensis in Loperamide-Induced Constipation of SD Rats. Int. J. Mol. Sci. 2019, 20, 946

by
Ji Eun Kim
1,
Ji Won Park
1,
Mi Ju Kang
1,
Hyeon Jun Choi
1,
Su Ji Bae
1,
You Sang Choi
1,
Young Ju Lee
1,
Hee Seob Lee
2,
Jin Tae Hong
3 and
Dae Youn Hwang
1,*
1
Department of Biomaterial Science, College of Natural Resources and Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang 627-706, Republic of Korea
2
College of Human Ecology, Pusan National University, Busan 609-735, Republic of Korea
3
College of Pharmacy, Chungbuk National University, Chungju 361-763, Republic of Korea
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2026, 27(5), 2228; https://doi.org/10.3390/ijms27052228
Submission received: 30 October 2025 / Accepted: 5 December 2025 / Published: 27 February 2026
(This article belongs to the Section Bioactives and Nutraceuticals)
Browse Figure
Versions Notes
In the original publication [1], there was a mistake in Figure 4A as published. A TEM analysis for the ultrastructure of the colon was conducted to investigate the laxative effect of SPA. In the original figure, the “CNTR group” and “Lop + Vehicle group” were wrong. These TEM images were duplicated with those of the No group and Vehicle group in our published papers of another journal due to the negligence of insufficient careful inspection. In addition, the authors once again confirmed the accuracy of these figures from raw data for TEM images. The corrected version of Figure 4A appears below. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

Reference

  1. Kim, J.E.; Park, J.W.; Kang, M.J.; Choi, H.J.; Bae, S.J.; Choi, Y.S.; Lee, Y.J.; Lee, H.S.; Hong, J.T.; Hwang, D.Y. Anti-Inflammatory Response and Muscarinic Cholinergic Regulation during the Laxative Effect of Asparagus cochinchinensis in Loperamide-Induced Constipation of SD Rats. Int. J. Mol. Sci. 2019, 20, 946. [Google Scholar] [CrossRef] [Scilit] [PubMed]
Ijms 27 02228 g004
Figure 4. An ultrastructure image of the colon after SPA administration: (A) The ultrastructure of the crypt in the CNTR, SPA-, Lop + Vehicle- and Lop + SPA-treated groups were viewed by TEM at 4000× magnification. (B) The number of paneth cells, lipid droplets, and goblet cells were measured using Leica Application Suite (Leica Microsystems, Switzerland). The arrow indicates a lipid droplet distributed around the lumen of the crypt. Two to three rats per group were used in the TEM analysis, and each parameter was measured in duplicate in two different slides. The data are reported as the mean ± SD. * indicates p < 0.05 compared to the CNTR group. # indicates p < 0.05 compared to the Lop + Vehicle-treated group. Lm, lumen of crypt; Gb, goblet cells; Pn, paneth cells.
Figure 4. An ultrastructure image of the colon after SPA administration: (A) The ultrastructure of the crypt in the CNTR, SPA-, Lop + Vehicle- and Lop + SPA-treated groups were viewed by TEM at 4000× magnification. (B) The number of paneth cells, lipid droplets, and goblet cells were measured using Leica Application Suite (Leica Microsystems, Switzerland). The arrow indicates a lipid droplet distributed around the lumen of the crypt. Two to three rats per group were used in the TEM analysis, and each parameter was measured in duplicate in two different slides. The data are reported as the mean ± SD. * indicates p < 0.05 compared to the CNTR group. # indicates p < 0.05 compared to the Lop + Vehicle-treated group. Lm, lumen of crypt; Gb, goblet cells; Pn, paneth cells.
Ijms 27 02228 g004
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MDPI and ACS Style

Kim, J.E.; Park, J.W.; Kang, M.J.; Choi, H.J.; Bae, S.J.; Choi, Y.S.; Lee, Y.J.; Lee, H.S.; Hong, J.T.; Hwang, D.Y. Correction: Kim et al. Anti-Inflammatory Response and Muscarinic Cholinergic Regulation During the Laxative Effect of Asparagus cochinchinensis in Loperamide-Induced Constipation of SD Rats. Int. J. Mol. Sci. 2019, 20, 946. Int. J. Mol. Sci. 2026, 27, 2228. https://doi.org/10.3390/ijms27052228

AMA Style

Kim JE, Park JW, Kang MJ, Choi HJ, Bae SJ, Choi YS, Lee YJ, Lee HS, Hong JT, Hwang DY. Correction: Kim et al. Anti-Inflammatory Response and Muscarinic Cholinergic Regulation During the Laxative Effect of Asparagus cochinchinensis in Loperamide-Induced Constipation of SD Rats. Int. J. Mol. Sci. 2019, 20, 946. International Journal of Molecular Sciences. 2026; 27(5):2228. https://doi.org/10.3390/ijms27052228

Chicago/Turabian Style

Kim, Ji Eun, Ji Won Park, Mi Ju Kang, Hyeon Jun Choi, Su Ji Bae, You Sang Choi, Young Ju Lee, Hee Seob Lee, Jin Tae Hong, and Dae Youn Hwang. 2026. "Correction: Kim et al. Anti-Inflammatory Response and Muscarinic Cholinergic Regulation During the Laxative Effect of Asparagus cochinchinensis in Loperamide-Induced Constipation of SD Rats. Int. J. Mol. Sci. 2019, 20, 946" International Journal of Molecular Sciences 27, no. 5: 2228. https://doi.org/10.3390/ijms27052228

APA Style

Kim, J. E., Park, J. W., Kang, M. J., Choi, H. J., Bae, S. J., Choi, Y. S., Lee, Y. J., Lee, H. S., Hong, J. T., & Hwang, D. Y. (2026). Correction: Kim et al. Anti-Inflammatory Response and Muscarinic Cholinergic Regulation During the Laxative Effect of Asparagus cochinchinensis in Loperamide-Induced Constipation of SD Rats. Int. J. Mol. Sci. 2019, 20, 946. International Journal of Molecular Sciences, 27(5), 2228. https://doi.org/10.3390/ijms27052228

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