Prostaglandin E1-Mediated Collateral Recruitment Is Delayed in a Neonatal Rat Stroke Model
Abstract
:1. Introduction
2. Results
2.1. Neonatal Ischemia Induces Thromboxane a Synthase-1 Gene Expression
2.2. PgE1 Induces Delayed Blood-Flow Redistribution in the Ipsilateral Side
2.3. PgE1 Reduces Thromboxane a Synthase-1 Expression and Lesion Size
3. Discussion
4. Materials and Methods
4.1. Neonatal Ischemia-Reperfusion
4.2. Drug Treatment
4.3. Sample Size Calculation
4.4. Quantitative Polymerase Chain Reaction Analysis
4.5. Ultrasound Imaging
4.6. Measurement of Infarct Volume
4.7. Immunohistochemistry
4.8. Statistical Analysis
Supplementary Materials
Author contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Bonnin, P.; Pansiot, J.; Baud, O.; Charriaut-Marlangue, C. Prostaglandin E1-Mediated Collateral Recruitment Is Delayed in a Neonatal Rat Stroke Model. Int. J. Mol. Sci. 2018, 19, 2995. https://doi.org/10.3390/ijms19102995
Bonnin P, Pansiot J, Baud O, Charriaut-Marlangue C. Prostaglandin E1-Mediated Collateral Recruitment Is Delayed in a Neonatal Rat Stroke Model. International Journal of Molecular Sciences. 2018; 19(10):2995. https://doi.org/10.3390/ijms19102995
Chicago/Turabian StyleBonnin, Philippe, Julien Pansiot, Olivier Baud, and Christiane Charriaut-Marlangue. 2018. "Prostaglandin E1-Mediated Collateral Recruitment Is Delayed in a Neonatal Rat Stroke Model" International Journal of Molecular Sciences 19, no. 10: 2995. https://doi.org/10.3390/ijms19102995