Table of Contents
Int. J. Mol. Sci., Volume 18, Issue 3 (March 2017)
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Cover Story (view full-size image) The synthesis of β-ODAP begins with the formation of β-(isoxazolin-5-on-2-yl)alanine (BIA) from the [...] Read more. The synthesis of β-ODAP begins with the formation of β-(isoxazolin-5-on-2-yl)alanine (BIA) from the reaction of O-acetylserine and isoxazolin-5-one. β-cyanoalanine synthase (CAS) uses isoxazolin-5-one as an alternative nucleophile in the reaction. BIA is proposed for conversion to the short-lived intermediate, 2,3,-L-diaminopropanoic acid, which is subsequently oxalylized by oxalyl-coenzyme A to form β-ODAP. View this paper.