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Int. J. Mol. Sci. 2015, 16(3), 6113-6123;

In Vitro Corrosion and Cytocompatibility Properties of Nano-Whisker Hydroxyapatite Coating on Magnesium Alloy for Bone Tissue Engineering Applications

Departmentof Dentistry, Shanghai Tenth People's Hospital, Tongji University, Shanghai 200072, China
Shanghai Key Laboratory of Development and Application for Metal-Functional Materials, School of Materials Science and Engineering, Tongji University, Shanghai 201804, China
Department of Urology, Huashan Hospital, Fudan University, Shanghai 200031, China
Department of Science and Technology, Southern Medical University, Guangzhou 510515, China
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Mohamed N. Rahaman
Received: 15 December 2014 / Revised: 19 January 2015 / Accepted: 17 February 2015 / Published: 17 March 2015
(This article belongs to the Special Issue Biomaterials for Tissue Engineering)
Full-Text   |   PDF [5110 KB, uploaded 17 March 2015]   |  


We report here the successful fabrication of nano-whisker hydroxyapatite (nHA) coatings on Mg alloy by using a simple one-step hydrothermal process in aqueous solution. The nHA coating shows uniform structure and high crystallinity. Results indicate that nHA coating is promising for improving the in vitro corrosion and cytocompatibility properties of Mg-based implants and devices for bone tissue engineering. In addition, the simple hydrothermal deposition method used in the current study is also applicable to substrates with complex shapes or surface geometries. View Full-Text
Keywords: biodegradable Mg alloy; hydroxyapatite; hydrothermal process biodegradable Mg alloy; hydroxyapatite; hydrothermal process

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Yang, H.; Yan, X.; Ling, M.; Xiong, Z.; Ou, C.; Lu, W. In Vitro Corrosion and Cytocompatibility Properties of Nano-Whisker Hydroxyapatite Coating on Magnesium Alloy for Bone Tissue Engineering Applications. Int. J. Mol. Sci. 2015, 16, 6113-6123.

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