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Molecules, Volume 27, Issue 23

December-1 2022 - 526 articles

Cover Story: Recently, chiral metal-organic frameworks (MOFs) have drawn increasing attention for asymmetric reactions. The intrinsic chiral environments in rigid MOFs provide confinement effects and specific interactions, leading to shape-, size-, chemo- and enantioselectivity. DFT calculations is a prevalent tool to investigate the fundamental mechanism and provide an in-depth understanding of the relationship of structure with catalytic performance. In this work, a DFT study revealed that structural distortion and non-covalent interaction of chiral rigid In-MOF provided the inherent driving force for the enantioselectivity of asymmetric catalysis. This theoretical investigation provides a microscopic insight for the reaction mechanism, and it is useful for the development of new chiral MOFs toward asymmetric reactions. View this paper
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Articles (526)

  • Article
  • Open Access
10 Citations
4,342 Views
21 Pages

Appraisal of the Antioxidant Activity, Polyphenolic Content, and Characterization of Selected Himalayan Herbs: Anti-Proliferative Potential in HepG2 Cells

  • Sumaira Yousuf,
  • Shabnam Shabir,
  • Simran Kauts,
  • Tarun Minocha,
  • Ahmad A. Obaid,
  • Anmar A. Khan,
  • Abdulrahman Mujalli,
  • Yahya F. Jamous,
  • Sarah Almaghrabi and
  • Bandar K. Baothman
  • + 4 authors

6 December 2022

Natural antioxidants derived from plants have played a vital role in preventing a wide range of human chronic conditions and provide novel bioactive leads for investigators in pharmacotherapy discovery. This work was designed to examine the ethnophar...

  • Article
  • Open Access
14 Citations
2,909 Views
14 Pages

The Quality and Bacterial Community Changes in Freshwater Crawfish Stored at 4 °C in Vacuum Packaging

  • Liang Qiu,
  • Yunchun Zhao,
  • Hui Ma,
  • Xiaofei Tian,
  • Chan Bai and
  • Tao Liao

6 December 2022

Crawfish can be easily spoiled due to their rich nutrition and high water content, which is difficult to preserve. In this study, the dominant spoilage organisms in crawfish which were stored at 4 °C in vacuum packaging were identified by high-th...

  • Article
  • Open Access
48 Citations
4,691 Views
13 Pages

Carbon Dots Derived from Tea Polyphenols as Photosensitizers for Photodynamic Therapy

  • Yuxiang Yang,
  • Haizhen Ding,
  • Zijian Li,
  • Antonio Claudio Tedesco and
  • Hong Bi

6 December 2022

Photodynamic therapy (PDT) has become an emerging cancer treatment method. Choosing the photosensitizer (PS) compounds is one of the essential factors that can influence the PDT effect and action. Carbon dots (CDs) have shown great potential as photo...

  • Review
  • Open Access
13 Citations
5,683 Views
15 Pages

Zebrafish Models for Skeletal Muscle Senescence: Lessons from Cell Cultures and Rodent Models

  • Shogo Ichii,
  • Izumi Matsuoka,
  • Fumiyoshi Okazaki and
  • Yasuhito Shimada

6 December 2022

Human life expectancy has markedly increased over the past hundred years. Consequently, the percentage of elderly people is increasing. Aging and sarcopenic changes in skeletal muscles not only reduce locomotor activities in elderly people but also i...

  • Review
  • Open Access
20 Citations
4,898 Views
46 Pages

6 December 2022

Marigold (Calendula), an important asteraceous genus, has a history of many centuries of therapeutic use in traditional and officinal medicines all over the world. The scientific study of Calendula metabolites was initiated at the end of the 18th cen...

  • Article
  • Open Access
7 Citations
2,353 Views
17 Pages

Study on Oil Recovery Mechanism of Polymer-Surfactant Flooding Using X-ray Microtomography and Integral Geometry

  • Daigang Wang,
  • Yang Song,
  • Ping Wang,
  • Guoyong Li,
  • Wenjuan Niu,
  • Yuzhe Shi and
  • Liang Zhao

6 December 2022

Understanding pore-scale morphology and distribution of remaining oil in pore space are of great importance to carry out in-depth tapping of oil potential. Taking two water-wet cores from a typical clastic reservoir in China as an example, X-ray CT i...

  • Article
  • Open Access
4 Citations
2,655 Views
16 Pages

FOXO3a Mediates Homologous Recombination Repair (HRR) via Transcriptional Activation of MRE11, BRCA1, BRIP1, and RAD50

  • Gozde Inci,
  • Madhuri Shende Warkad,
  • Beom-Goo Kang,
  • Na-Kyung Lee,
  • Hong-Won Suh,
  • Soon Sung Lim,
  • Jaebong Kim,
  • Sung-Chan Kim and
  • Jae-Yong Lee

6 December 2022

To test whether homologous recombination repair (HRR) depends on FOXO3a, a cellular aging model of human dermal fibroblast (HDF) and tet-on flag-h-FOXO3a transgenic mice were studied. HDF cells transfected with over-expression of wt-h-FOXO3a increase...

  • Article
  • Open Access
19 Citations
2,966 Views
16 Pages

Osthole Suppresses Knee Osteoarthritis Development by Enhancing Autophagy Activated via the AMPK/ULK1 Pathway

  • Teng Ma,
  • Xiangpeng Wang,
  • Wenjing Qu,
  • Lingsen Yang,
  • Cheng Jing,
  • Bingrui Zhu,
  • Yongkui Zhang and
  • Wenpeng Xie

6 December 2022

Knee osteoarthritis (KOA) is an increasingly prevalent heterogeneous disease characterized by cartilage erosion and inflammation. As the main chemical constituent of Angelicae Pubescentis Radix (APR), an anti-inflammatory herbal medicine, the potenti...

  • Article
  • Open Access
13 Citations
2,888 Views
22 Pages

6 December 2022

Bioactive compounds from olive mill pomace (OMP) were extracted through a two-step solid-liquid extraction procedure considering four factors at five levels of a central composite rotatable response surface design. The influence of the process variab...

  • Article
  • Open Access
6 Citations
2,088 Views
12 Pages

6 December 2022

The cyclization of di-(2,6-difluorophenyl)maleindinitrile with magnesium(II) and zinc(II) acetates in boiling ethylene glycol is applied to synthesize Mg(II) and Zn(II) complexes of the octa-(2,6-difluorophenyl)tetraazaporphyrin. The compounds are id...

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Molecules - ISSN 1420-3049