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Molecules, Volume 26, Issue 16

August-2 2021 - 405 articles

Cover Story: DNA origami nanostructures are frequently employed as substrates for the single-molecule investigation of biomolecular reactions by in situ atomic force microscopy. This requires their immobilization at atomically flat surfaces such as mica, which is typically achieved by addition of millimolar concentrations of Mg2+ ions. These non-physiological Mg2+ concentrations, however, may interfere with the reactions and processes under investigation. Therefore, in this article, different strategies for efficient DNA origami immobilization at mica surfaces under essentially Mg2+-free conditions have been evaluated. Pre-adsorption of polycations such as spermidine has been identified as a particularly promising strategy, the efficiency of which, however, depends on the employed solution conditions and the DNA origami shape. View this paper.
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Articles (405)

  • Review
  • Open Access
30 Citations
5,881 Views
11 Pages

22 August 2021

Amyloidosis is a term referring to a group of various protein-misfolding diseases wherein normally soluble proteins form aggregates as insoluble amyloid fibrils. How, or whether, amyloid fibrils contribute to tissue damage in amyloidosis has been the...

  • Article
  • Open Access
9 Citations
3,884 Views
15 Pages

Effects of a Peripherally Restricted Hybrid Inhibitor of CB1 Receptors and iNOS on Alcohol Drinking Behavior and Alcohol-Induced Endotoxemia

  • Luis Santos-Molina,
  • Alexa Herrerias,
  • Charles N. Zawatsky,
  • Ozge Gunduz-Cinar,
  • Resat Cinar,
  • Malliga R. Iyer,
  • Casey M. Wood,
  • Yuhong Lin,
  • Bin Gao and
  • George Kunos
  • + 1 author

22 August 2021

Alcohol consumption is associated with gut dysbiosis, increased intestinal permeability, endotoxemia, and a cascade that leads to persistent systemic inflammation, alcoholic liver disease, and other ailments. Craving for alcohol and its consequences...

  • Article
  • Open Access
26 Citations
5,328 Views
15 Pages

22 August 2021

Effect of temperature and pH on the interaction of curcumin with β-casein was explored by fluorescence spectroscopy, ultraviolet-visible spectroscopy and molecular dynamics simulation. The spectroscopic results showed that curcumin could bind to β-ca...

  • Article
  • Open Access
5 Citations
2,799 Views
13 Pages

22 August 2021

Accurate and precise application of ion-selective electrodes (ISEs) in the quantification of environmental pollutants is a strenuous task. In this work, the electrochemical response of alendronate sodium trihydrate (ALN) was evaluated by the fabricat...

  • Review
  • Open Access
61 Citations
13,203 Views
25 Pages

Effects of Insecticides and Microbiological Contaminants on Apis mellifera Health

  • Aleksandra Leska,
  • Adriana Nowak,
  • Ireneusz Nowak and
  • Anna Górczyńska

22 August 2021

Over the past two decades, there has been an alarming decline in the number of honey bee colonies. This phenomenon is called Colony Collapse Disorder (CCD). Bee products play a significant role in human life and have a huge impact on agriculture, the...

  • Review
  • Open Access
39 Citations
5,855 Views
51 Pages

Olive Trees By-Products as Sources of Bioactive and Other Industrially Useful Compounds: A Systematic Review

  • Valentina Lo Giudice,
  • Immacolata Faraone,
  • Maria Roberta Bruno,
  • Maria Ponticelli,
  • Fabiana Labanca,
  • Donatella Bisaccia,
  • Carmine Massarelli,
  • Luigi Milella and
  • Luigi Todaro

22 August 2021

The need to produce an ever-increasing quantity of material products and food resulting from the planet globalization process has contributed to the spread of modern agriculture based on a linear production resulting in the generation of tons of wast...

  • Article
  • Open Access
6 Citations
5,375 Views
21 Pages

Synthesis of 3,5-Bis(trifluoromethyl)phenyl-Substituted Pyrazole Derivatives as Potent Growth Inhibitors of Drug-Resistant Bacteria

  • Ibrahim S. Alkhaibari,
  • Hansa Raj KC,
  • Subrata Roy,
  • Mohd. K. Abu-gazleh,
  • David F. Gilmore and
  • Mohammad A. Alam

22 August 2021

Enterococci and methicillin-resistant S. aureus (MRSA) are among the menacing bacterial pathogens. Novel antibiotics are urgently needed to tackle these antibiotic-resistant bacterial infections. This article reports the design, synthesis, and antimi...

  • Article
  • Open Access
6 Citations
4,834 Views
15 Pages

Synthesis of Catechol Derived Rosamine Dyes and Their Reactivity toward Biogenic Amines

  • Filipe Monteiro-Silva,
  • Carla Queirós,
  • Andreia Leite,
  • María T. Rodríguez,
  • María J. Rojo,
  • Tomás Torroba,
  • Rui C. Martins,
  • Ana M. G. Silva and
  • Maria Rangel

22 August 2021

Functional organic dyes play a key role in many fields, namely in biotechnology and medical diagnosis. Herein, we report two novel 2,3- and 3,4-dihydroxyphenyl substituted rosamines (3 and 4, respectively) that were successfully synthesized through a...

  • Article
  • Open Access
6 Citations
3,456 Views
15 Pages

An Efficient Synthesis of 2-CF3-3-Benzylindoles

  • Vasiliy M. Muzalevskiy,
  • Zoia A. Sizova and
  • Valentine G. Nenajdenko

22 August 2021

The reaction of α-CF3-β-(2-nitroaryl) enamines with benzaldehydes afforded effectively α,β-diaryl-CF3-enones having nitro group. Subsequent reduction of nitro group by NH4HCO2-Pd/C system initiated intramolecular cyclization to give 2-CF3-3-benzylind...

  • Article
  • Open Access
10 Citations
3,536 Views
13 Pages

Synergistic Catalysis of SnO2/Reduced Graphene Oxide for VO2+/VO2+ and V2+/V3+ Redox Reactions

  • Yongguang Liu,
  • Yingqiao Jiang,
  • Yanrong Lv,
  • Zhangxing He,
  • Lei Dai and
  • Ling Wang

22 August 2021

In spite of their low cost, high activity, and diversity, metal oxide catalysts have not been widely applied in vanadium redox reactions due to their poor conductivity and low surface area. Herein, SnO2/reduced graphene oxide (SnO2/rGO) composite was...

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Molecules - ISSN 1420-3049