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Volume 24
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10.3390/molecules24234343
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Open AccessArticle

Synthesis of Bis-Glyoxylamide Peptidomimetics Derived from Bis-N-acetylisatins Linked at C5 by a Methylene or Oxygen Bridge

by
Venty Suryanti
1,
Ruonan Zhang
2,
Vina Aldilla
2,
Mohan Bhadbhade
3,
Naresh Kumar
2 and
David StC Black
2,*
1
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Sebelas Maret University, Jl. Ir. Sutami 36A Surakarta, Jawa Tengah 57126, Indonesia
2
School of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia
3
Solid State and Elemental Analysis Unit, Mark Wainwright Analytical Centre, Division of Research, The University of New South Wales, Sydney, NSW 2052, Australia
*
Author to whom correspondence should be addressed.
Academic Editor: Mário J.F. Calvete
Molecules 2019, 24(23), 4343; https://doi.org/10.3390/molecules24234343
Received: 29 October 2019 / Revised: 20 November 2019 / Accepted: 22 November 2019 / Published: 27 November 2019
(This article belongs to the Special Issue Indole Derivatives: Synthesis and Application)
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Abstract

The bis-glyoxylamide peptidomimetics have been synthesized from bis-N-acetylisatins linked at C5 by ring-opening with alcohols, amines, and amino acid methyl ester hydrochlorides. X-ray images of single crystals of bis-glyoxylamide peptidomimetics have been obtained. View Full-Text
Keywords: antimicrobial peptides; N-acetylisatins; glyoxylamides; peptidomimetics; quorum sensing antimicrobial peptides; N-acetylisatins; glyoxylamides; peptidomimetics; quorum sensing
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MDPI and ACS Style

Suryanti, V.; Zhang, R.; Aldilla, V.; Bhadbhade, M.; Kumar, N.; Black, D.S. Synthesis of Bis-Glyoxylamide Peptidomimetics Derived from Bis-N-acetylisatins Linked at C5 by a Methylene or Oxygen Bridge. Molecules 2019, 24, 4343. https://doi.org/10.3390/molecules24234343

AMA Style

Suryanti V, Zhang R, Aldilla V, Bhadbhade M, Kumar N, Black DS. Synthesis of Bis-Glyoxylamide Peptidomimetics Derived from Bis-N-acetylisatins Linked at C5 by a Methylene or Oxygen Bridge. Molecules. 2019; 24(23):4343. https://doi.org/10.3390/molecules24234343

Chicago/Turabian Style

Suryanti, Venty; Zhang, Ruonan; Aldilla, Vina; Bhadbhade, Mohan; Kumar, Naresh; Black, David S. 2019. "Synthesis of Bis-Glyoxylamide Peptidomimetics Derived from Bis-N-acetylisatins Linked at C5 by a Methylene or Oxygen Bridge" Molecules 24, no. 23: 4343. https://doi.org/10.3390/molecules24234343

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