You are currently viewing a new version of our website. To view the old version click .

Molecules, Volume 24, Issue 14

July-2 2019 - 160 articles

Cover Story: Predominantly spread in West Tropical Africa, the shrub Salacia senegalensis (Lam.) DC has mainly gained it reputation due to its antimalarial effects. However, its leaves are widely used in the treatment of skin diseases, particularly in Guinea-Bissauan folk medicine.
With this study, the plant S. senegalensis was valorized due to its antidermatophytic and anti-inflammatory properties, providing scientific evidence on its ethnomedicinal uses against skin diseases. Relevantly, the hydroethanolic extract obtained from the leaves did not lead to detrimental effects towards the keratinocyte cell line HaCaT. The flavonoid profile of S. senegalensis leaves was also disclosed for the first time. View this paper.
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (160)

  • Article
  • Open Access
13 Citations
4,501 Views
13 Pages

Structural and Biological Investigations for a Series of N-5 Substituted Pyrrolo[3,2-d]pyrimidines as Potential Anti-Cancer Therapeutics

  • Brian M. Cawrse,
  • Nia’mani M. Robinson,
  • Nina C. Lee,
  • Gerald M. Wilson and
  • Katherine L. Seley-Radtke

23 July 2019

Pyrrolo[3,2-d]pyrimidines have been studied for many years as potential lead compounds for the development of antiproliferative agents. Much of the focus has been on modifications to the pyrimidine ring, with enzymatic recognition often modulated by...

  • Article
  • Open Access
19 Citations
7,372 Views
26 Pages

Identification of Metabolites of Eupatorin in Vivo and in Vitro Based on UHPLC-Q-TOF-MS/MS

  • Luya Li,
  • Yuting Chen,
  • Xue Feng,
  • Jintuo Yin,
  • Shenghao Li,
  • Yupeng Sun and
  • Lantong Zhang

23 July 2019

Eupatorin is the major bioactive component of Java tea (Orthosiphon stamineus), exhibiting strong anticancer and anti-inflammatory activities. However, no research on the metabolism of eupatorin has been reported to date. In the present study, ultra-...

  • Article
  • Open Access
6 Citations
3,348 Views
9 Pages

Chalcogen Bonding due to the Exo-Substitution of Icosahedral Dicarbaborane

  • Jindřich Fanfrlík,
  • Drahomír Hnyk and
  • Pavel Hobza

23 July 2019

Chalcogen atoms are a class of substituents capable of generating inner and outer derivatives of boron clusters. It is well known that chalcogenated boron clusters can form strong σ-hole interactions when a chalcogen atom is a part of an icosah...

  • Review
  • Open Access
86 Citations
7,432 Views
26 Pages

What are the Main Sensor Methods for Quantifying Pesticides in Agricultural Activities? A Review

  • Roy Zamora-Sequeira,
  • Ricardo Starbird-Pérez,
  • Oscar Rojas-Carillo and
  • Seiling Vargas-Villalobos

23 July 2019

In recent years, there has been an increase in pesticide use to improve crop production due to the growth of agricultural activities. Consequently, various pesticides have been present in the environment for an extended period of time. This review pr...

  • Article
  • Open Access
53 Citations
5,477 Views
14 Pages

23 July 2019

Dendrobium officinale is a herb in traditional Chinese medicine where D. officinale polysaccharides (DOP) are the main active ingredient. This study aimed at evaluating DOP efficiency at inhibiting 1-Methyl-2-nitro-1-nitrosoguanidine (MNNG) induced p...

  • Article
  • Open Access
76 Citations
6,815 Views
19 Pages

23 July 2019

In this study, the photothermal-induced bactericidal activity of phospholipid-decorated gold nanorods (DSPE-AuNR) suspension against Pseudomonas aeruginosa planktonic and biofilm cultures was investigated. We found that the treatment of planktonic cu...

  • Article
  • Open Access
17 Citations
5,508 Views
17 Pages

Carbon Nanotube and Cellulose Nanocrystal Hybrid Films

  • Mingzhe Jiang,
  • Robert Seney,
  • Paul Charles Bayliss and
  • Christopher L. Kitchens

23 July 2019

The use of cellulose nanocrystals (CNC) in high performance coatings is attractive for micro-scale structures or device fabrication due to the anisotropic geometry, however CNC are insulating materials. Carbon nanotubes (CNT) are also rod-shaped nano...

  • Article
  • Open Access
25 Citations
4,922 Views
15 Pages

23 July 2019

In order to enrich and separate three coumarins (columbianetin acetate, osthole and columbianadin) from Angelicae Pubescentis Radix (APR), an efficient method was established by combining macroporous resins (MARs) with preparative high-performance li...

  • Article
  • Open Access
17 Citations
7,264 Views
15 Pages

23 July 2019

Polyurea (PU) nano-capsules have received voluminous interest in various fields due to their biocompatibility, high mechanical properties, and surface functionality. By incorporating magnetic nanoparticle (MNPs) into the polyurea system, the attribut...

  • Article
  • Open Access
61 Citations
8,577 Views
14 Pages

Diallyl Disulfide Induces Apoptosis and Autophagy in Human Osteosarcoma MG-63 Cells through the PI3K/Akt/mTOR Pathway

  • Ziqi Yue,
  • Xin Guan,
  • Rui Chao,
  • Cancan Huang,
  • Dongfang Li,
  • Panpan Yang,
  • Shanshan Liu,
  • Tomoka Hasegawa,
  • Jie Guo and
  • Minqi Li

23 July 2019

Diallyl disulfide (DADs), a natural organic compound, is extracted from garlic and scallion and has anti-tumor effects against various tumors. This study investigated the anti-tumor activity of DADs in human osteosarcoma cells and the mechanisms. MG-...

of 16

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Molecules - ISSN 1420-3049