You are currently viewing a new version of our website. To view the old version click .

Molecules, Volume 22, Issue 8

August 2017 - 149 articles

Cover Story: Enzymatically synthesized LacNAc tetrasaccharides were conjugated to BSA protein scaffolds by squarate linker chemistry. Resulting multivalent neo-glycoproteins were further studied for specific binding of the tumor-associated human galectin 3 (Gal-3) and its truncated counterpart Gal-3∆. We observed a significantly increased affinity of Gal-3∆ to neo-glycoproteins presenting LacNAc type 1 repeating units. This is the first evidence for differences in glycan selectivity of Gal-3∆ and Gal-3 and may be further utilized for tracing Gal-3∆ during tumor progression and therapy. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (149)

  • Article
  • Open Access
19 Citations
14,024 Views
8 Pages

Base-Mediated One-Pot Synthesis of Aliphatic Diazirines for Photoaffinity Labeling

  • Lei Wang,
  • Zetryana Puteri Tachrim,
  • Natsumi Kurokawa,
  • Fumina Ohashi,
  • Yasuko Sakihama,
  • Yasuyuki Hashidoko and
  • Makoto Hashimoto

22 August 2017

Aliphatic diazirines have been widely used as prominent photophores for photoaffinity labeling owing to their relatively small size which can reduce the steric effect on the natural interaction between ligands and proteins. Based on our continuous ef...

  • Article
  • Open Access
5 Citations
6,192 Views
11 Pages

The Potential of α-Spinasterol to Mimic the Membrane Properties of Natural Cholesterol

  • Ivan Haralampiev,
  • Holger A. Scheidt,
  • Daniel Huster and
  • Peter Müller

22 August 2017

Sterols play a unique role for the structural and dynamical organization of membranes. The current study reports data on the membrane properties of the phytosterol (3β,5α,22E)-stigmasta-7,22-dien-3-β-ol (α-spinasterol), which represents an important...

  • Article
  • Open Access
146 Citations
15,991 Views
10 Pages

Antioxidant and Anticancer Activities of Essential Oil from Gannan Navel Orange Peel

  • Chao Yang,
  • Hui Chen,
  • Hongli Chen,
  • Balian Zhong,
  • Xuzhong Luo and
  • Jiong Chun

22 August 2017

China is one of the leading producers of citrus in the world. Gannan in Jiangxi Province is the top navel orange producing area in China. In the present study, an essential oil was prepared by cold pressing of Gannan navel orange peel followed by mol...

  • Article
  • Open Access
19 Citations
6,400 Views
14 Pages

Cloning and Characterization of Two Iridoid Synthase Homologs from Swertia Mussotii

  • Beibei Xiang,
  • Xiaoxue Li,
  • Yan Wang,
  • Xiaoxuan Tian,
  • Zhen Yang,
  • Lin Ma,
  • Xia Liu and
  • Yong Wang

22 August 2017

Swertia mussotii is an important medicinal plant found on the Qinghai Tibetan Plateau that has great economic and medicinal value. This plant has enjoyed a long history of use as a curative for hepatitis. The biological activity of secoiridoids, incl...

  • Article
  • Open Access
4 Citations
4,288 Views
7 Pages

Cryochemical Synthesis of Polymorphous Nanostructures of a Steroid Neurohormone

  • Yurii Morozov,
  • Dmitry Chistyakov,
  • Vladimir Chernyshev and
  • Gleb Sergeev

21 August 2017

A new cryochemical strategy of producing nanoparticles and polymorphous nanostructures of drugs is used, which is based on the dynamic combination of high and low temperatures, gas and solid phases, and inert carrier gases. This technology is applied...

  • Article
  • Open Access
30 Citations
5,729 Views
12 Pages

21 August 2017

Abstract: To observe the effects of refined Xiaoyaosan (XYS) on the depressive-like behaviors in rats with chronic unpredictable mild stress (CUMS), and to explore the relationship between the changes of neurosteroids and mRNA expressions of their sy...

  • Review
  • Open Access
48 Citations
9,075 Views
40 Pages

The Genus Alnus, A Comprehensive Outline of Its Chemical Constituents and Biological Activities

  • Xueyang Ren,
  • Ting He,
  • Yanli Chang,
  • Yicheng Zhao,
  • Xiaoyi Chen,
  • Shaojuan Bai,
  • Le Wang,
  • Meng Shen and
  • Gaimei She

21 August 2017

The genus Alnus (Betulaceae) is comprised of more than 40 species. Many species of this genus have a long history of use in folk medicines. Phytochemical investigations have revealed the presence of diarylheptanoids, polyphenols, flavonoids, terpenoi...

  • Article
  • Open Access
28 Citations
6,993 Views
17 Pages

21 August 2017

The current study describes the composition of Salvia lavandulifolia (Vahl) essential oils (SlEOs) obtained from plants cultivated in Murcia (Spain), as determined by gas chromatography. Relative and absolute concentrations, the enantiomeric ratios o...

  • Article
  • Open Access
13 Citations
5,735 Views
11 Pages

Chemical Constituents of Murraya tetramera Huang and Their Repellent Activity against Tribolium castaneum

  • Chun-Xue You,
  • Shan-Shan Guo,
  • Wen-Juan Zhang,
  • Zhu-Feng Geng,
  • Jun-Yu Liang,
  • Ning Lei,
  • Shu-Shan Du and
  • Zhi-Wei Deng

20 August 2017

Sixteen compounds were isolated from the leaves and stems of Murraya tetramera Huang. Based on the NMR and MS spectral results, the structures were determined. It was confirmed that the isolated compounds included three new compounds (9, 10 and 13) a...

  • Article
  • Open Access
84 Citations
7,358 Views
13 Pages

Tissue-Specific Accumulation of Sulfur Compounds and Saponins in Different Parts of Garlic Cloves from Purple and White Ecotypes

  • Gianfranco Diretto,
  • Angela Rubio-Moraga,
  • Javier Argandoña,
  • Purificación Castillo,
  • Lourdes Gómez-Gómez and
  • Oussama Ahrazem

20 August 2017

This study set out to determine the distribution of sulfur compounds and saponin metabolites in different parts of garlic cloves. Three fractions from purple and white garlic ecotypes were obtained: the tunic (SS), internal (IS) and external (ES) par...

of 15

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Molecules - ISSN 1420-3049