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Open AccessArticle

Antioxidant and Anticancer Activities of Essential Oil from Gannan Navel Orange Peel

National Navel Orange Engineering Research Center, College of Life and Environmental Sciences, Gannan Normal University, Ganzhou 34100, China
Author to whom correspondence should be addressed.
Molecules 2017, 22(8), 1391;
Received: 28 July 2017 / Revised: 20 August 2017 / Accepted: 21 August 2017 / Published: 22 August 2017
(This article belongs to the Special Issue Essential Oils: Chemistry and Bioactivity)
China is one of the leading producers of citrus in the world. Gannan in Jiangxi Province is the top navel orange producing area in China. In the present study, an essential oil was prepared by cold pressing of Gannan navel orange peel followed by molecular distillation. Its chemical composition was analyzed by GC-MS. Twenty four constituents were identified, representing 97.9% of the total oil. The predominant constituent was limonene (74.6%). The anticancer activities of this orange essential oil, as well as some of its major constituents, were investigated by MTT assay. This essential oil showed a positive effect on the inhibition of the proliferation of a human lung cancer cell line A549 and prostate cancer cell line 22RV-1. Some of the oil constituents displayed high anticancer potential and deserve further study. View Full-Text
Keywords: Gannan navel orange; essential oil; GC-MS; anticancer Gannan navel orange; essential oil; GC-MS; anticancer
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Yang, C.; Chen, H.; Chen, H.; Zhong, B.; Luo, X.; Chun, J. Antioxidant and Anticancer Activities of Essential Oil from Gannan Navel Orange Peel. Molecules 2017, 22, 1391.

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